Microfluidic device for detection of five indicators of sound child rearing

Abstract

The present invention discloses a microfluidic device for detection of five indicators of sound child rearing, the microfluidic device includes a microfluidic chip, a temperature control module, a micro motor moving module and a CCD detection module, through the mutual matching of the micro motor moving module, the temperature control module and the microfluidic chip, the processes of capture of target cell specific antigens and cleaning of cell antigens non-specifically adsorbed on microsphere surface by use of antibodies coating the microsphere surface, capture of enzyme labelled antibodies by use of the target cell antigens non-specifically adsorbed on the microsphere surface and catalytic chemiluminiscence of an excitation liquid by use of enzymes non-specifically adsorbed on the microsphere surface and the like can be respectively completed, the CCD detection module is cooperated for acquisition and detection of chemicalluminescence signals on the microsphere surface so as to achieve integration operation of the capture and detection process of five indicator antigens of sound child rearing in serum samples; the five indicators of sound child rearing comprise TOX (Toxoplasma gondii), RUB (Rubella), CMV (cytomegalovirus), HSV-1 (herpe-1), and HSV-2 (herpe-2).

Description

technical field [0001] The invention relates to the field of life medical detection and diagnosis, in particular to a method for detecting five indicators of prenatal and postnatal care: toxoplasma gondii (TOX), rubella (RUB), giant cell (CMV), herpes (HSV-1), herpes (HSV-2) and other five kinds of IgG (immunoglobulin) antibody level microfluidic chip and detection device. Background technique [0002] Primary intrauterine infection in early pregnancy seriously affects fetal development and causes similar clinical symptoms and signs, so the five prenatal and postnatal care checks are particularly important. Among them, cytomegalovirus (CMV) is an infectious disease caused by cytomegalovirus (CMV) infection. The primary infection of pregnant women can cause great harm to the fetus; viremia in pregnant women can cause premature birth, miscarriage, stillbirth and various congenital diseases. Deformation, the virus can be transmitted to the fetus through the placenta, causing t...

AI Technical Summary

Problems solved by technology

Traditional detection methods often rely on large-scale biomedical diagnostic instruments, which are expensive, complex detection process, high detection cost, long detection time and low efficiency, which is not conducive to the clinical promotion and popularization of this diagnostic method

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