A kind of antitumor pharmaceutical composition containing total flavonoids of apocynum leaf

A technology of anti-tumor drugs and compositions, which is applied in the direction of anti-tumor drugs, drug combinations, and medical preparations containing active ingredients, etc., which can solve the problems of lack of effective therapeutic drugs and intervention methods, high risk, and occurrence of cardiovascular diseases in the treatment of chemotherapy. high risk issues
CN107115372BActive Publication Date: 2020-07-07任立群
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
任立群
Publication Date
2020-07-07

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Abstract

Relating to the field of pharmacy, the invention in particular provides an anti-tumor pharmaceutical composition containing total flavonoids of apocynum venetum leaves. The pharmaceutical composition is composed of total flavonoids of apocynum venetum leaves and an anthracycline drug, wherein the anthracycline drug is pirarubicin or epirubicin. The pharmaceutical composition provided by the invention has better antitumor effect than anthracycline drugs, also effectively alleviates or avoids the cardiac toxicity of patients, and reduces the toxic and side effects.
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Description

technical field

[0001] The invention relates to the field of pharmacy, in particular to an antitumor pharmaceutical composition containing total flavonoids of apocynum leaves with synergistic effect and cardiotoxicity protection. Background technique

[0002] Tumor disease is currently one of the frequently-occurring diseases of human beings, which has brought great pain to patients. At present, chemotherapy is the main treatment for tumors. Pain other than the disease itself, mild such as headache, nausea, fatigue, severe such as hair loss, liver and kidney and heart toxicity and so on.

[0003] Anthracyclines, such as epirubicin and pirarubicin, have been widely used in the treatment of hematological malignancies and solid tumors, such as breast cancer, lymphoma, and acute leukemia. It has good effect on anti-tumor. The 2014 "NCCN Guidelines for Breast Cancer" recommended that the preferred adjuvant chemotherapy regimen for breast cancer is AC×4→T(P)×4 (doxorubicin, epir...

Claims

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