Photoacousticblood glucose detection method and device for automatically positioning vessels

Abstract

The invention provides a photoacousticblood glucose detection method and device for automatically positioning vessels. The device comprises an excitation light source device, a sample device, a detection device and a signal processing device. Theexcitation light source device comprises a laser, a diaphragm, a collimating lens and a focusing lens, wherein the detection device comprises a backwardultrasonic detector, a lateralultrasonic detector, a scanning mobile platform, a mobile platformcontroller and a miniaturefocusing controller; the signal processing device comprises a signal amplifier, a signal acquisition card and a computer which are electrically connected in sequence. The lateralultrasonic detector is fixed on the scanning mobile platform and moves with the scanning mobile platform, and the scanning mobile platform is connected with thecomputer through the mobile platform controller. The input terminal of the signal amplifier is respectively connected with thebackwardultrasonic detector and the lateralultrasonic detector, and the signal acquisition card is connected with the laser. The device and the method realize photoacoustic detection on blood sugar concentration in vessels, and greatly improve the accuracy.

Description

technical field [0001] The invention belongs to the technical field of biomedicine, and in particular relates to a photoacoustic blood sugar detection device and method for automatic blood vessel positioning. Background technique [0002] At present, the number of people suffering from diabetes in the world has exceeded 400 million, and my country is the country with the largest number of diabetic patients in the world. Diabetes has become one of the three major killers that seriously threaten people's life, health and quality of life. So far, the medical treatment of diabetes can only be through regular tracking and measurement of blood sugar levels and changes, together with drugs to regulate the metabolic function of insulin, so as to control the blood sugar concentration in the body and stabilize it. Therefore, whether the measurement of blood sugar and its changes is accurate or not plays a very important role in the control of diabetes. The traditional blood glucose m...

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Problems solved by technology

Studies have shown that there are great differences in the distribution of blood glucose concentration in the epidermis, dermis, subcutaneous tissue and blood vessels of the human body. Although the blood glucose value in the skin tissue fluid is also used to indirectly reflect the blood glucose concentration in the blood, its correlation Whether it is completely correct is not yet conclusive, and is still in the research stage

Moreover, other human tissue parts contain the interference of many components (such as: fat, fibrous tissue and bone, etc.), making it difficult to extract the photoacoustic signal of the measured blood glucose characteristics

In addition, studies have also shown that there is a certain time-delay effect between the blood glucose concentration in other human tissue parts (such as interstitial fluid in the skin) and the whole blood blood glucose concentration in blood vessels. The precise measurement of content and change trend has a certain influence

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