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Detergent for medical instrumentation

一种二醇溶剂、表面活性剂的技术，应用在洗涤剂组合物、洗涤剂配合剂、非表面活性洗涤剂组合物等方向，能够解决泡沫、干扰医疗器械清洁等问题

Inactive Publication Date: 2017-12-01
WHITELEY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0014] The presence of surfactants in formulations can lead to unwanted foam that interferes with the cleaning of medical devices

Method used

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  • Detergent for medical instrumentation
  • Detergent for medical instrumentation
  • Detergent for medical instrumentation

Examples

Experimental program
Comparison scheme
Effect test

example 12

[0107] The following examples present formulations with lower concentrations of ingredients.

[0108]

%w / w

Deionized water

44.93

boric acid

1.00

sodium gluconate

1.00

Dowanol DPM

44.89

50% Sodium Hydroxide

0.64

85% Triethanolamine

3.99

85% phosphoric acid

1.40

Properase L 1600

2.00

Mergal K20

0.15

[0109] When used, the dilution of this preparation should be 5ml / liter

[0110] Scrubber Disinfector Test

[0111] The formulation of Example 9 was tested in a series of different washer-disinfectors. A typical cycle in testing consists of a cold water prewash followed by a main wash cycle.

[0112]After the wash cycle, two rinse cycles are carried out, with the last rinse cycle at a temperature of 90°C to sanitize the dirt loaded. During the wash cycle, the load compartment was visually monitored for foaming. Also, multiple wash tests should be performed on each rack in ...

example 13

[0115] Example 13: Preparation of Potassium Salt Formulation

[0116] In this example, a formulation similar to Example 9 was prepared, but potassium salt was used instead of sodium salt. Since potassium gluconate is not readily available in the market, gluconolactone was used. During the preparation of Example, gluconolactone was reacted with potassium hydroxide to produce potassium gluconate salt.

[0117] Table 7

[0118] Element

%w / w

Deionized water

38.49

48% potassium hydroxide solution

3.58

Gluconolactone

3.57

Source of Gluconic Acid

boric acid

0.87

Inorganic acid

Propylene Glycol

17.49

85% Triethanolamine

17.49

85% phosphoric acid

6.12

Properase L1600

8.75

protease

Spezyme AA

3.50

Amylase

Mergal K20

0.13

preservative

[0119] The final formulation had a specific gravity of 1.1345 and a refractive index of 1.4...

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PUM

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Abstract

A cleaning composition comprising: a. At least one alkanolamine b. At least one mineral acid c. At least one salt of a hydroxycarboxylic acid d. At least one protease enzyme; wherein said composition contains no surfactant.

Description

technical field [0001] The present invention relates to a cleaning composition which produces little or no foam in use and which is useful for the automatic cleaning of medical, surgical and other instruments. Background technique [0002] For successful reprocessing of used medical instruments, e.g., forceps, retractors, scissors, speculums, rigid endoscopes, flexible endoscopes, etc., all biofouling needs to be removed from the instruments prior to sterilization or disinfection , for example, blood, fat, tissue fragments, etc. Any residual soil left on the equipment will most likely adversely affect the sterilization or disinfection process, resulting in nosocomial infection for the next patient exposed to the contaminated instrument. [0003] Typically, most medical devices are automatically reprocessed in a washer-disinfector. For most surgical instruments, the washer-disinfectors used are usually provided with multiple spray arms. Load instruments into trays and plac...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C11D7/32C11D7/42C11D7/08C11D7/26A61L2/16
CPCC11D7/08C11D7/265C11D7/3218C11D3/386C11D2111/20C11D7/40C11D7/5077B08B3/08C11D2111/10
Inventor T·O·格拉斯贝C·D·霍夫曼P·J·摩根N·A·罗伯茨
Owner WHITELEY
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