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Traditional Chinese medicine extract for treating rheumatoid arthritis and preparation method theroef

A rheumatoid and extract technology, which is applied in the field of traditional Chinese medicine extract and its preparation for the treatment of rheumatoid arthritis, can solve the problems of single action target and reverse the disease, and achieve good reproducibility, easy operation, and simple process Effect

Inactive Publication Date: 2018-01-16
HEILONGJIANG UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above drugs all have various adverse reactions and side effects, such as gastrointestinal side effects, infection, allergic reaction, skin irritation, liver and kidney damage, etc., and the target of action is single, mainly to improve the condition and delay the course of the disease, and cannot be obtained from radically reverse the disease

Method used

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Examples

Experimental program
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Embodiment Construction

[0013] The present invention adopts the rat arthritis model induced by complete Freund's adjuvant to carry out pharmacodynamics experiment in vivo, evaluates the drug effect of pseudophyllum extract in treating rheumatoid arthritis, and illustrates that pseudophyllum extract is effective in treating rheumatoid arthritis. Drug use in inflammation.

[0014] The present invention will be further described in detail below. It should be pointed out that the following description is only an illustration of the technical solutions claimed in the present invention, and is not any limitation to these technical solutions. The protection scope of the present invention shall be determined by the contents described in the appended claims.

[0015] 1 Experimental sample

[0016] Add 10 times the amount of 70% ethanol to the pseudo-acid berry medicinal material and soak for 12 hours, heat and reflux extraction 3 times, 2 hours each time, to obtain the ethanol extract, filter and combine th...

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Abstract

The invention relates to a preparation method of extract of fruits of nicandra physaloides and medical application thereof for treating rheumatoid arthritis. The extract of nicandra physaloides is prepared from the fruits of nicandra physaloides. Proofed by experiment study, the extract has obvious function on treating the rheumatoid arthritis.

Description

Technical field: [0001] The present invention relates to pseudoacid berries (fruits of Nicandra physaloides ) extract and its medicinal application for treating rheumatoid arthritis. Background technique: [0002] Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by joint synovitis. The latest epidemiological survey shows that the incidence of RA is high all over the world, accounting for about 0.5-1.1% of the total global population. The prevalence rate in my country is 0.32%-0.36%. According to the results of the sixth census, it is estimated that there are about 5 million patients in the country. The northern part of my country is the high incidence area of ​​this disease, and the patients are more than 25-50 years old. The early lesions of RA patients mainly include joint redness, swelling, heat pain and dysfunction, which affect the movable joints and cause widespread inflammation of the connective tissue throughout the body. In severe cases, i...

Claims

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Application Information

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IPC IPC(8): A61K36/81A61P29/00A61P19/02
Inventor 杨炳友刘艳夏永刚匡海学
Owner HEILONGJIANG UNIV OF CHINESE MEDICINE
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