Lactobacillus plantarum improving easily-fat body and offspring weight and application thereof

Abstract

The invention provides a lactobacillus plantarum improving easily-fat body and offspring weight and application thereof, and is preserved in the General Microbiology Center of China Microbiological Culture Collection Management Committee, and the preservation number is CGMCC No.14570. The lactobacillus plantarum has excellent acid and bile salt resistance, bile salt hydrolase activity and intestinal colonization ability. Animal experiments and human food experiments show that the lactobacillus plantarum can control weight gain of pregnant women and offsprings caused by a high-fat and high-sugar diet by bile salt hydrolase activity and regulating intestinal flora, at the same time, the lactobacillus plantarum can regulate the intestinal flora, optimize intestinal flora structure, increase number of beneficial bacteria, and improve ratio of bacteroidetes and firmicutes, thereby improving the easily-fat body. The animal experiments and human food experiments show that the lactobacillus plantarum has clear efficacy and high safety, and can reverse the easily-fat body by fundamentally improving the intestinal flora of humans, has a long-lasting non-rebound effect, and has great potential for market development.

Description

technical field [0001] The invention belongs to the technical field of microbes, and more specifically relates to a strain of Lactobacillus plantarum LP-A3 which can control the body weight of parents and offspring and improve obesity-prone physique by regulating intestinal flora and its application. Background technique [0002] With the improvement of people's living standards and changes in lifestyle, the incidence of obesity has risen rapidly. According to the World Health Organization, the number of obese people has doubled since 1980. In 2014, there were 1.9 billion overweight people in the world. [0003] Obesity not only threatens the health of the individual, but also threatens the health of offspring. A large number of studies at home and abroad have shown that obesity during pregnancy is associated with many adverse pregnancy outcomes, such as gestational diabetes, gestational hypertension, dystocia, premature delivery, cesarean section, macrosomia, and prolonge...

AI Technical Summary

Problems solved by technology

However, in the actual use of Lactobacillus plantarum, although some Lactobacillus plantarum can control body weight and regulate fat metabolism, it does not necessarily have a beneficial effect on offspring, nor does it improve the structure of intestinal flora, reverse The role of obesity

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