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A kind of alkaline cleaning solution and preparation method thereof

A cleansing liquid and alkaline technology, applied in chemical instruments and methods, surface active detergent compositions, detergent compositions, etc., can solve problems such as high medical costs, increased consumption expenses of hospital laboratory departments, and expensive HITERGENT stock solution , to achieve the effect of simple preparation method, excellent cleaning effect and reduced medical cost

Active Publication Date: 2020-12-25
ZHONGSHAN CHUANGYI BIOCHEM ENG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are very limited patent reports on the alkaline cleaning solution of the Roche biochemical analyzer, but the alkaline cleaning solution is a necessity for the daily operation of the instrument. The carryover rate of contamination and the cleaning of cuvettes, sample needles, and pipes require a large amount of alkaline cleaning solution every day, and the original HITERGENT stock solution is expensive, which increases the consumption expenditure of the laboratory department of the hospital and leads to high medical costs.

Method used

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  • A kind of alkaline cleaning solution and preparation method thereof
  • A kind of alkaline cleaning solution and preparation method thereof
  • A kind of alkaline cleaning solution and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] An alkaline cleaning solution, each liter of alkaline cleaning solution contains:

[0025] Tridecyl isomeric alcohol polyoxyethylene ether (TO-13) 5.0g,

[0026] NaOH 38.0g.

[0027] Accurately weigh the required materials according to the above formula amount, completely dissolve the weighed NaOH in 800mL deionized water, add tridecyl isomerized alcohol polyoxyethylene ether (TO-13) and stir to dissolve, and make the volume to 1L , the pH value of the measured solution was 12.90, the conductivity was 160.1ms / cm, and the alkaline cleaning solution was obtained after filtration.

[0028] 1. Experimental method

[0029] 1.1 Comparative experiment

[0030] All detection items are first calibrated with a full set of original reagents. Fasting venous serum was taken from 30 healthy subjects, and after washing with Roche original alkaline cleaning solution, the Roche Modular P800 biochemical analyzer analyzed the total protein (TP), albumin (ALB), alanine aminotransferase...

Embodiment 2

[0054] An alkaline cleaning solution, each liter of alkaline cleaning solution contains:

[0055] Tridecyl isomeric alcohol polyoxyethylene ether (TO-13) 6g,

[0056] NaOH 42g.

[0057] Accurately weigh the required materials according to the above formula, completely dissolve the weighed NaOH in 700mL of deionized water, add tridecyl isomerized alcohol polyoxyethylene ether (TO-13) and stir to dissolve, and set the volume to 1L , the pH value of the measured solution was 13.1, and the conductivity was 167.1ms / cm. After filtering, the alkaline cleaning solution was obtained.

Embodiment 3

[0059] An alkaline cleaning solution, each liter of alkaline cleaning solution contains:

[0060] Tridecyl isomeric alcohol polyoxyethylene ether (TO-13) 2g,

[0061] NaOH 32g.

[0062] Accurately weigh the required materials according to the above formula, completely dissolve the weighed NaOH in 750mL of deionized water, add tridecyl isomerized alcohol polyoxyethylene ether (TO-13) and stir to dissolve, and set the volume to 1L , the pH value of the measured solution was 11.8, and the conductivity was 154.3ms / cm. After filtering, the alkaline cleaning solution was obtained.

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Abstract

The invention discloses an alkaline cleaning liquid. Each liter of the alkaline cleaning liquid contains 1-10 g of isotridecyl alcohol polyoxyethylene ether, 30-50 g of NaOH and the balance of deionized water. The alkaline cleaning liquid provided by the invention has an excellent cleaning effect; the cleaning effect is consistent with the cleaning effect of an original cleaning liquid; the preparation method of the alkaline cleaning liquid is simple and the reagent cost is low; the price of the alkaline cleaning liquid is lower than the price of cleaning liquids also used for a biochemical analyzer in the market; and therefore the alkaline cleaning liquid is beneficial to reducing the medical cost.

Description

technical field [0001] The invention belongs to the field of in vitro diagnosis, relates to an alkaline cleaning solution and a preparation method thereof, and more specifically relates to an alkaline cleaning solution used in a Roche biochemical analyzer and a preparation method thereof. Background technique [0002] Due to its easy operation, reliable results and stable performance, the automatic biochemical analyzer has become an indispensable instrument and equipment in the laboratory department of the hospital. The Roche Modular P800 biochemical analyzer produced by Roche Company in Germany has the advantages of fast detection speed, easy operation, low failure rate, good system repeatability, high accuracy, and modular combination, and has become the first choice for hospitals. [0003] At present, there are very limited patent reports on the alkaline cleaning solution of the Roche biochemical analyzer, but the alkaline cleaning solution is a necessity for the daily op...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C11D1/72C11D3/04G01N35/00
CPCC11D1/72C11D3/044G01N35/00
Inventor 李冰彭金燕
Owner ZHONGSHAN CHUANGYI BIOCHEM ENG