Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Establishment method for cyclocarya paliurus particle HPLC fingerprint spectrum

A technology of fingerprints and establishment methods, which is applied in the field of establishment of HPLC fingerprints of Cyanocarya granules, achieves the effects of good repeatability, strong operability, and ensuring safety and effectiveness

Active Publication Date: 2018-08-21
广西中道医药科技有限公司
View PDF2 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no literature report on the research on the HPLC fingerprints of Cyclocarya granules. The present invention establishes the HPLC fingerprints of Cyclocarya granules through high-performance liquid chromatography, and compares them with the Chinese medicine chromatographic fingerprint similarity evaluation system. It is of great significance to analyze it to provide a basis for distinguishing other varieties and quality control of Cyclocarya paliurus

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Establishment method for cyclocarya paliurus particle HPLC fingerprint spectrum
  • Establishment method for cyclocarya paliurus particle HPLC fingerprint spectrum
  • Establishment method for cyclocarya paliurus particle HPLC fingerprint spectrum

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Instrument: Agilent High Performance Liquid Chromatograph.

[0023] Medicinal materials: Qingqianliu granules provided by Guangxi Zhuangyao Pharmaceutical Engineering Technology Research Center; Qingqianliu, a reference medicinal material, was provided by Guangxi Alili Health Technology Co., Ltd.

[0024] Reagents: mobile phase A acetonitrile is chromatographically pure, water is ultrapure water, and the rest of the reagents are analytical pure.

[0025] Preparation of test solution: accurately weigh 1.0 g of Cyclocarya serrata granules, place in a round-bottom flask, add 50 mL petroleum ether, reflux and extract for 2-3 hours, discard petroleum ether, evaporate the medicine residue, and precisely add 20 mL acetonitrile. Weigh the mass, dissolve it by ultrasonic for 30 min, acetonitrile makes up the lost mass, shake well, filter through the microporous membrane, and take the continuous filtrate to obtain the test solution.

[0026] Preparation of the reference solution: Take th...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
wavelengthaaaaaaaaaa
Login to View More

Abstract

The invention provides an establishment method for a cyclocarya paliurus particle HPLC fingerprint spectrum. The establishment method comprises the following steps: preparing a sample for test; determining chromatographic conditions; and using a high performance liquid chromatograph for measurement so as to obtain the cyclocarya paliurus particle HPLC fingerprint spectrum. The chemical informationof cyclocarya paliurus particles is expressed comprehensively and accurately, the fingerprint spectrum has the characteristics of common peaks such as relatively high degree of separation, preferablepeak form, high repeatability, high operability and the like, and the quality of the cyclocarya paliurus particles can be controlled effectively.

Description

Technical field [0001] The invention relates to the field of quality control of traditional Chinese medicine preparations, in particular to a method for establishing HPLC fingerprint of Qingqianliu granules. Background technique [0002] Cyclobalanopsis cylindrica is a plant of the Juglans family Cyclobalanopsis genus. According to the records of "Chinese Materia Medica", it has the effects of dispelling wind, anti-inflammatory and relieving pain, killing insects and relieving itching. Folks mostly use its leaves as a medicinal part, with a long history of use. Modern studies have shown that Cymbidium aureum leaves have the effects of producing body fluids, quenching thirst, lowering blood sugar, lowering blood pressure, and prolonging life. It can be used to treat diabetes, hypertension, neurasthenia, etc. Existing literature reports use the determination of the content of quercetin and kaempferin in Cyclobalanopsis as the quality control standard for medicinal materials. Howev...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): G01N30/02G01N30/06
CPCG01N30/02G01N30/06
Inventor 赵立春钟余特王雪于培良李俊秀
Owner 广西中道医药科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com