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Composition for improving tolerance of skin and preparation method of composition

A composition and tolerance technology, applied in the field of compositions for improving skin tolerance and preparation thereof, can solve problems such as insignificant effects

Active Publication Date: 2018-09-07
GUANGZHOU SOYAWA BIO TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Nowadays, most of the methods used by the cosmetics industry to increase skin tolerance are to enhance the "mortar" structure in the skin by supplementing exogenous ceramides, cholesterol and other substances, and the effect is not obvious

Method used

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  • Composition for improving tolerance of skin and preparation method of composition
  • Composition for improving tolerance of skin and preparation method of composition
  • Composition for improving tolerance of skin and preparation method of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] A composition for improving skin tolerance: Alteromonas fermentation product extract 8g, β-glucan 0.5g, wild soybean (GLYCINE SOJA) seed extract 0.8g, glycosphingolipids 0.5g, deionized 15 g of water, 0.8 g of glycerin, and 1.5 g of 1,3-butanediol.

[0045] The preparation method is:

[0046] (1) Take β-glucan and Alteromonas fermented product extract, add it to wild soybean (GLYCINESOJA) seed extract, stir until completely uniform, and then use a homogenizer to homogenize for 1.5 minutes, reserve raw material Ⅰ;

[0047] (2) Mix water, glycerin, 1,3-butanediol, and glycosphingolipids evenly, inject them into a high-pressure, high-shear nano-homogenizer, heat up to 60-65°C, homogenize for 3 minutes, and cycle 6 times , to obtain spare raw material Ⅱ;

[0048] (3) Mix spare raw material I and spare raw material II uniformly to obtain a liquid preparation.

Embodiment 2

[0050] A composition for improving skin tolerance: Alteromonas fermentation product extract 12g, β-glucan 1.5g, wild soybean (GLYCINE SOJA) seed extract 1.2g, glycosphingolipids 1.0g, deionized 25 g of water, 1.2 g of glycerin, and 2.5 g of 1,3-butanediol.

[0051] The preparation method is:

[0052] (1) Take β-glucan and Alteromonas fermented product extract, add it to wild soybean (GLYCINESOJA) seed extract, stir until completely uniform, and then use a homogenizer to homogenize for 2.5 minutes, reserve raw material I;

[0053] (2) Mix water, glycerin, 1,3-butanediol, and glycosphingolipids evenly, inject them into a high-pressure, high-shear nano-homogenizer, heat up to 60-65°C, homogenize for 6 minutes, and cycle 3 times , to obtain spare raw material Ⅱ;

[0054] (3) Mix spare raw material I and spare raw material II uniformly to obtain a liquid preparation.

Embodiment 3

[0056] A composition for improving skin tolerance: Alteromonas fermentation product extract 10g, β-glucan 1g, wild soybean (GLYCINE SOJA) seed extract 1g, glycosphingolipids 0.8g, deionized water 20g Parts by weight, 1 g of glycerin, 2 g of 1,3-butanediol.

[0057] The preparation method is:

[0058] (1) Take β-glucan and Alteromonas fermentation product extract, add it to GLYCINESOJA seed extract, stir until completely uniform, then homogenize with a homogenizer for 2 minutes, reserve raw material I;

[0059] (2) Mix water, glycerin, 1,3-butanediol, and glycosphingolipids evenly, inject them into a high-pressure, high-shear nano-homogenizer, heat up to 60-65°C, homogenize for 4.5 minutes, and cycle 5 times , to obtain spare raw material Ⅱ;

[0060] (3) Mix spare raw material I and spare raw material II uniformly to obtain a liquid preparation.

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Abstract

The invention belongs to the technical field of biomedicine or the technical field of cosmetics and discloses a composition for improving the tolerance of skin and a preparation method of the composition; the composition is prepared from the following raw materials: alteromonas fermentation product extract and beta-glucan; furthermore, the composition is prepared from the following raw materials:the alteromonas fermentation product extract, the beta-glucan, glycine soja seed extract and glycosphingolipids; the raw materials are prepared into a liquid preparation and the hemolytic rate causedby SDS (Sodium Dodecyl Sulfate) can be remarkably reduced; the liquid preparation provided by the invention is added into the cosmetics and has a very good effect of improving the tolerance of the skin.

Description

technical field [0001] The invention belongs to the technical field of biomedicine or cosmetics, and in particular relates to a composition for improving skin tolerance and a preparation method thereof. Background technique [0002] Tolerance (Tolerance) refers to a state in which the human body is less responsive to drugs, which can be divided into congenital and acquired according to its nature. Tolerance is a biological phenomenon that is a natural consequence of drug use. [0003] Skin tolerance refers to the skin's ability to resist the outside world, mainly refers to the ability to resist external stimuli. Skin with poor tolerance can be divided into three main groups: Hypersensitive skin: such as atopic dermatitis or skin with a tendency to rosacea. Atopic skin is characterized by abnormal stratum corneum permeability and a predisposition to itch, whereas rosacea-prone skin develops a vasocongestive response to irritation. Induced skin sensitivity: Factors that inc...

Claims

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Application Information

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IPC IPC(8): A61K8/99A61K8/9789A61K8/73A61K8/68A61Q19/00
CPCA61K8/68A61K8/73A61K8/9789A61K8/99A61K2800/10A61Q19/00
Inventor 陈柏辉
Owner GUANGZHOU SOYAWA BIO TECH CO LTD
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