Application of phosphorus-based material in preparing medicine for treating tumor

A phosphorus-based, tumor-based technology, applied in the field of medicine, can solve the problems of not being used as an anticancer drug, and the drug has no targeting and specificity, and achieve the effect of inhibiting tumor cell proliferation and high biocompatibility

Active Publication Date: 2018-09-11
HUBEI MOPHOS TECH CO LTD
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

Similarly, the black phosphorus nanosheets in the composite material play the role of anticancer drug...

Method used

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  • Application of phosphorus-based material in preparing medicine for treating tumor
  • Application of phosphorus-based material in preparing medicine for treating tumor
  • Application of phosphorus-based material in preparing medicine for treating tumor

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Embodiment Construction

[0023] Below in conjunction with specific embodiment, further illustrate the present invention. It should be understood that these examples are only used to illustrate the present invention and are not intended to limit the scope of the present invention. In addition, it should be understood that after reading the teachings of the present invention, those skilled in the art can make various changes or modifications to the present invention, and these equivalent forms also fall within the scope defined by the appended claims of the present application.

[0024] First, bioactive black phosphorus nanosheets were prepared by liquid phase exfoliation. The specific steps include: in an air-isolated environment, grind a certain amount of black phosphorus crystals, disperse them in a solvent and seal them. The solvent can use various organic solvents, such as N-methylpyrrolidone (NMP), dimethylformamide (DMF), dimethyl sulfoxide (DMSO), absolute ethanol, isopropanol, etc.; and then u...

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Abstract

The invention discloses the application of a phosphorus-based material in preparing medicine for treating tumors. Phosphorus-based materials can be converted to the material producing phosphate ions including in acidic environments, and phosphorus-based materials produce large amounts of phosphate ions through phagocytosis by tumor cells to change the internal and external environment of the cells, thereby inhibiting the proliferation of the tumor cells and inducing the death of the tumor cells. This process has no significant effect on normal cell activity. In the method, the phosphorus-basedmaterial is applied to the preparation of medicine for treating tumors, the amplification and the transfer of the tumor cells can be effectively inhibited, the metastasis of the tumor cells and the relapse of the tumor can be effectively prevented, the tumor effect is improved, and the medicine has small influence on normal cells and tissues during the treatment process, and is safe and reliable.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to the application of a phosphorus-based material in the preparation of drugs for treating tumors. Background technique [0002] Chemotherapy and its interventional methods combined with surgery and radiotherapy are the main methods of clinical treatment of tumors and cancers. However, because chemotherapy drug molecules have similar toxic effects on cancer cells and normal cells, the actual treatment process is often accompanied by serious side effects, damage to human organs and hematopoietic function, and some can cause hair loss, severe anemia, digestive dysfunction and immune function damage etc. At the same time, the current treatment methods and chemotherapy drugs have not fundamentally effectively solved the difficult problems of cancer treatment, such as cancer recurrence, metastasis and severe impairment of immune function are still the main causes of death. [0003] Th...

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Application Information

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IPC IPC(8): A61K33/42A61P35/00A61P35/04A61P35/02
CPCA61K33/42A61P35/00A61P35/02A61P35/04
Inventor 喻学锋周文华潘婷崔浩东
Owner HUBEI MOPHOS TECH CO LTD
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