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Natural pharmaceutical composition as well as traditional Chinese medicine composition containing same and application of natural pharmaceutical composition

A technology of natural medicines and compositions, which can be applied to drug combinations, medical preparations containing active ingredients, medical raw materials derived from ferns/filamentous plants, etc., can solve the problems of lack of clinical interventions for preventing sepsis, etc. Achieve the effect of preventing and reversing organ failure, good safety, and improving quality of life

Active Publication Date: 2018-11-06
TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, antibiotics and infusion are the main interventions for the treatment of sepsis, and there is still a lack of clinical interventions for the prevention of sepsis

Method used

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  • Natural pharmaceutical composition as well as traditional Chinese medicine composition containing same and application of natural pharmaceutical composition
  • Natural pharmaceutical composition as well as traditional Chinese medicine composition containing same and application of natural pharmaceutical composition
  • Natural pharmaceutical composition as well as traditional Chinese medicine composition containing same and application of natural pharmaceutical composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] The embodiment of the present invention provides a natural medicine composition, which comprises the following raw materials in the weight ratio: 40 parts of paeoniflorin, 1 part of ferulic acid, 10 parts of hydroxysafflower yellow, and 1 part of protocatechualdehyde.

Embodiment 2

[0045] The embodiment of the present invention provides a natural medicine composition, which includes the following raw materials in the weight ratio: 80 parts of paeoniflorin, 2 parts of ferulic acid, 20 parts of hydroxysafflower yellow, and 2 parts of protocatechualdehyde.

Embodiment 3

[0047] The embodiment of the present invention provides a natural medicine composition, which includes raw materials in the following weight proportions: 120 parts of paeoniflorin, 3 parts of ferulic acid, 30 parts of hydroxysafflower yellow, and 3 parts of protocatechualdehyde.

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PUM

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Abstract

The invention relates to a natural pharmaceutical composition as well as a traditional Chinese medicine composition containing the same and application of the natural pharmaceutical composition. The natural composition comprises the following raw materials in weight ratio: 40 to 200 parts of paeoniflorin, 1 to 20 parts of ferulic acid, 10 to 50 parts of hydroxysafflor yellow and 1 to 20 parts of protocatechuic aldehyde. The traditional Chinese medicine composition is a composition containing the natural pharmaceutical. The natural pharmaceutical composition and the traditional Chinese medicinecomposition have anti-aGvHD and anti-fungal infection effects, and are of great significance to improve the success rate of transplantation, improve the prognosis of patients, and increase the long-term survival rate of patients with hematological diseases, recipients of allogeneic hematopoietic stem cells and patients with fungal sepsis.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a natural medicine composition, a Chinese medicine composition containing the natural medicine and applications thereof. Background technique [0002] In the past 50 years, the continuous and rapid development of allogeneic hematopoietic stem cell transplantation (allo-HSCT) has become the most effective method to treat and even cure malignant hematological diseases. So far, more than 20,000 cases of allo-HSCT have been completed each year worldwide. However, the average long-term disease-free survival rate of allo-HSCT for various types of leukemia is only about 50%, which is mainly due to the Complications (mainly including graft-versus-host disease, pathogenic microorganism infection, etc.) seriously affect the prognosis and survival of patients. Therefore, finding safe and effective treatment methods to control the occurrence and development ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7048A61K31/192A61K31/351A61K31/11A61K36/71A61K36/65A61K36/734A61P31/10A61P37/06
CPCA61K31/11A61K31/192A61K31/351A61K31/7048A61K36/11A61K36/185A61K36/232A61K36/236A61K36/286A61K36/488A61K36/533A61K36/537A61K36/65A61K36/68A61K36/71A61K36/734A61P31/10A61P37/06A61K2300/00
Inventor 冯宇新潘桂湘朱彦樊官伟常艳旭王晓明王跃飞周正灿朱红艳尚婷
Owner TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
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