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Application of konjac flour to treatment and improvement of obesity

A technology of mannan and konjac glucomannan, which is applied in the direction of metabolic diseases and drug combinations, etc., can solve the problems of unreported effects on intestinal microbial communities, unclear and limited mechanism of konjac glucomannan's weight loss effect, etc., and achieve improvement The effect of obesity-related indicators

Inactive Publication Date: 2018-11-30
KUNMING UNIV OF SCI & TECH
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Problems solved by technology

Although the effect of konjac glucomannan (konjac flour, KF) as a prebiotic on obesity has been widely studied, the clinical results of konjac glucomannan in different studies often show relatively large inconsistencies, so the use of konjac flour One of the reasons for the limitation of glucomannan in weight control is that the mechanism of the weight loss effect of konjac glucomannan is not yet clear
The effect of konjac glucomannan on the intestinal microbial community has not been systematically reported

Method used

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  • Application of konjac flour to treatment and improvement of obesity
  • Application of konjac flour to treatment and improvement of obesity
  • Application of konjac flour to treatment and improvement of obesity

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Embodiment Construction

[0030] see Figure 1-Figure 5 As shown, the technical scheme adopted in this specific embodiment is: it is made up of the following aspects: the anti-fertility effect of konjac glucomannan intervention; the impact of konjac glucomannan intervention on inflammation; konjac glucomannan intervention on intestinal The regulation of gut microbiota; the effect of konjac glucomannan intervention on intestinal barrier function of colon; the effect of konjac glucomannan intervention on energy metabolism; the correlation between konjac glucomannan on gut microbiota and obesity.

[0031] Konjac glucomannan is used to treat and improve the application method of the application of obesity, and the specific steps are as follows:

[0032] a) dissolving konjac glucomannan in water, and administering according to the dosage of konjac glucomannan at 5-10 g / person / day;

[0033] b) Continuous administration.

[0034] The konjac glucomannan dissolved in water can be divided into two times a day....

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Abstract

Relating to the field of health, the invention relates to application of konjac flour to treatment and improvement of obesity. The invention consists of the following aspects: konjac flour intervenedanti-obesity effect; the influence of konjac flour intervention on inflammation; the regulating effect of konjac flour intervention on intestinal microorganisms; the influence of konjac flour intervention on colonic intestinal barrier function; the influence of konjac flour intervention on energy metabolism; and the correlation of konjac flour to intestinal microorganisms and obesity. The invention has the beneficial effects that: konjac flour not only can improve obesity-related indicators, but also can increase the diversity of intestinal microorganisms and improve the microbial community structure, promote the formation of beneficial bacteria and inhibit the growth of obesity-promoting bacteria.

Description

technical field [0001] The invention relates to the field of health, in particular to the application of konjac glucomannan for treating and improving obesity. Background technique [0002] Obesity is a major chronic disease prevalent in the world, which seriously threatens human health. Recent studies have shown that obesity is closely related to gut microbes. Disturbance of gut microbes may cause systemic chronic inflammation and trigger metabolic diseases such as obesity. As one of the components with rich content and complex structure in the diet, oligosaccharides cannot be directly digested and absorbed by the human body, but are decomposed and utilized by intestinal symbiotic bacteria to provide energy for them. Therefore, oligosaccharides are of great significance for maintaining intestinal microbial homeostasis and protecting the intestinal barrier, and are often called "prebiotics". Current studies have shown that certain specific oligosaccharides can regulate th...

Claims

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Application Information

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IPC IPC(8): A61K31/736A61P3/04
CPCA61P3/04A61K31/736
Inventor 孔祥阳陈明会洪晶安李昱杜余辉
Owner KUNMING UNIV OF SCI & TECH
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