Application of orange leaf extract in preparation of medicine for treating/preventing autoimmune orchitis

Abstract

The invention belongs to the technical field of biomedicine and discloses the application of orange leaf extract in the preparation of medicine for treating / preventing autoimmune orchitis. Using the leaves of citrus which is rich in resources in my country as raw material, the citrus leaf ethanol extract obtained by ethanol cold soaking is then eluted by macroporous resin, and the concentrate of ethanol and acetone eluted parts is combined, dispersed in water, and successively used After extraction with cyclohexane, ethyl acetate and n-butanol, it was concentrated. Pharmacological experiments show that the orange leaf extract has anti-autoimmune orchitis effect, and can be developed into a drug for treating / preventing autoimmune orchitis.

Description

technical field

[0001] The invention belongs to the technical field of biomedicine, and in particular relates to the application of orange leaf extract in preparing medicine for autoimmune orchitis. Background technique

[0002] Infertility has become a global medical and social problem. At present, about 15% of couples of childbearing age in the world suffer from infertility, of which about 50% are caused by male factors. With the postponement of the average childbearing age and the full liberalization of the two-child policy, the problem of infertility in my country has become increasingly prominent. According to the "China Infertility Status Survey Report" jointly issued by the China Population Association and the National Family Planning Commission in 2012, the infertility rate of China's childbearing population has climbed from 2.5%-3% 20 years ago to 12.5%-15 %, the number of patients has exceeded 40 million, that is, one in every eight couples has infertility problem...

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