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Cleaning fluid used for fluid-based thin-preparation cytologic tests

A liquid-based, cytological technology, applied in the directions of detergent compounding agent, detergent composition, inorganic/elemental detergent composition, etc., can solve the problems of restricting the popularization and application of technology, and achieve easy popularization, simple ingredients and low price. Effect

Inactive Publication Date: 2019-02-26
武汉宏强医疗器械有限公司
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  • Summary
  • Abstract
  • Description
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Problems solved by technology

Therefore, the existing technical problems have seriously restricted the popularization and application of the above-mentioned technologies.

Method used

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Examples

Experimental program
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Effect test

Embodiment 1

[0021] Embodiment 1, the cleaning liquid preparation method of the present invention is sodium azide 0.1%, potassium chloride 0.9%, ethanol 4.5%, isopropanol 2.8%, benzalkonium chloride 0.3-1.2%, surplus is purified water, let The above components are uniformly stirred and dissolved.

[0022] The cleaning solution prepared in the above embodiments reduces the cost of use during use, and effectively decomposes and removes impurities such as red blood cells and mucus clumps mixed in the cell sample when taking materials, so that the liquid-based thin-layer cells can be formed into sheets under the microscope. When inspecting: The background of the film reading is clear, and the exfoliated cells with diagnostic significance are complete, easy to distinguish, evenly and almost without accumulation, and are tiled on the slide production area of ​​the slide, which is easy to promote and saves the time for preparing reagents.

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Abstract

The invention provides a cleaning fluid used for fluid-based thin-preparation cytologic tests. The cleaning fluid consists of sodium azide, potassium chloride, ethanol, isopropanol, benzalkonium chloride and purified water. The cleaning fluid can reduce using costs, and effectively decompose and remove impurities such as erythrocyte and mucus masses mixed into cell samples during material obtaining, so that, when a liquid-based thin layer cell finished slice is detected by a microscope, the background of the reading slice can be intelligible and clear, exfoliated cells having diagnostic meaning are complete in form, easy to distinguish and uniform, and are tiled at a slice production area of a glass slide nearly without accumulation; and therefore, the cleaning fluid is easy to promote andcan save the time of preparing reagents.

Description

technical field [0001] The invention relates to the technical field of biological preparations; in particular, it relates to a cleaning solution used in liquid-based thin-layer cell sheeting technology. Background technique [0002] Liquid-based thin-layer cell film production technology is an integral part of pathological diagnosis, and the quality of film production technology directly affects whether pathologists can make correct pathological diagnosis. [0003] The third-generation cytology production technology—liquid-based sedimentation production, entered the Chinese market at the end of 2001. Compared with the traditional Pap smear examination, it significantly improved the satisfaction of specimens and the detection rate of abnormal cells, and solved the problem. Traditional smears have high false negative rate, high rate of lost cells, poor smear quality, excessive mucus, blood or inflammatory cells and other technical problems, which have made a significant contri...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C11D1/62C11D3/20C11D3/04C11D3/60
CPCC11D1/62C11D3/046C11D3/201C11D3/2017
Inventor 不公告发明人
Owner 武汉宏强医疗器械有限公司
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