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Procyanidine and traditional Chinese medicine extract composition and application thereof

A technology of proanthocyanidins and extracts, which is applied in the direction of drug combinations, food ingredients containing natural extracts, medical preparations containing active ingredients, etc., can solve the problems of no therapeutic drugs, etc., and achieve blood circulation promotion, good taste and simple process Effect

Inactive Publication Date: 2019-03-12
JIANGSU QIANYAOTANG GUOYI RES INST CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, endocrine disorders caused by deficiency of Qi and blood, stagnation of Qi and blood, or blood stasis due to Qi deficiency, etc., the cases of chloasma (Prurigo melasma), freckles, butterfly spots, yellow and rough skin, etc. have increased significantly, and until now there is no definite curative effect Therapeutic drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Preparation of traditional Chinese medicine extract

[0029] Weigh 150g of ginseng, 450g of angelica, 100g of Chuanqiong, and 550g of astragalus, respectively, and place them in an extraction tank, add 12.5kg of ethanol with a concentration of 75%, and soak them in a closed manner at 40°C for 168 hours, and every 6 hours during the soaking period Stir once, after the soaking is over, filter the soaking extract, recycle the soaking extract to ethanol to obtain the extract and store it in another device; add 10 kg of pure water to the dregs after the alcohol extraction, heat and decoct for 2 hours, Filter the decoction, add 6.25 kg of pure water to the dregs, heat and decoct for 1 hour, filter the decoction, add 3.75 kg of pure water to the dregs, heat and decoct for 0.5 hour, filter the decoction, and The three decoctions were combined, filtered, and when the filtrate was concentrated to a concentrated solution with a specific gravity of 1.0, it was combined with the abo...

Embodiment 2

[0031] Preparation of traditional Chinese medicine extract

[0032] Weigh 150g of ginseng, 450g of angelica, 100g of Chuanqiong, and 550g of astragalus, respectively, and place them in an extraction tank, add 12.5kg of ethanol with a concentration of 75%, and soak in airtight conditions at 38°C for 168 hours. During the soaking period, every 6 hours Stir once, after the soaking is over, filter the soaking extract, recycle the soaking extract to ethanol to obtain the extract and store it in another device; add 10 kg of pure water to the dregs after the alcohol extraction, heat and decoct for 2 hours, Filter the decoction, add 6.25 kg of pure water to the dregs, heat and decoct for 1 hour, filter the decoction, add 3.75 kg of pure water to the dregs, heat and decoct for 0.5 hour, filter the decoction, and The three decoctions were combined, filtered, and when the filtrate was concentrated to a concentrated solution with a specific gravity of 1.0, it was combined with the above-m...

Embodiment 3

[0034] Preparation of traditional Chinese medicine extract

[0035] Weigh 150g of ginseng, 450g of angelica, 100g of Chuanqiong, and 550g of astragalus, respectively, and place them in an extraction tank, add 12.5kg of ethanol with a concentration of 75%, and soak for 168 hours at 42°C. During the soaking period, every 6 hours Stir once, after the soaking is over, filter the soaking extract, recycle the soaking extract to ethanol to obtain the extract and store it in another device; add 10 kg of pure water to the dregs after the alcohol extraction, heat and decoct for 2 hours, Filter the decoction, add 6.25 kg of pure water to the dregs, heat and decoct for 1 hour, filter the decoction, add 3.75 kg of pure water to the dregs, heat and decoct for 0.5 hour, filter the decoction, and The three decoctions were combined, filtered, and when the filtrate was concentrated to a concentrated solution with a specific gravity of 1.0, it was combined with the above-mentioned extract, and t...

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PUM

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Abstract

The invention belongs to the field of healthcare product processing, and provides a pharmaceutical composition. The pharmaceutical composition comprises, by weight, 2.5-5% of procyanidine and 95-97.5%of traditional Chinese medicine extract. A method for preparing the pharmaceutical composition includes sequentially progressively increasingly adding the procyanidine with the low weight into the traditional Chinese medicine extract by the aid of an equal progressive increase process; sufficiently grinding the procyanidine and the traditional Chinese medicine extract until the procyanidine and the traditional Chinese medicine extract are uniform; sieving the procyanidine and the traditional Chinese medicine extract to obtain the pharmaceutical composition. The pharmaceutical composition hasthe advantages that beneficial effects of resisting oxidation and scavenging free radicals can be realized by the procyanidine, effects of benefiting qi, removing blood stasis, regulating menstruation, removing freckle and nourishing skin can be realized by traditional Chinese medicine compositions, and accordingly good auxiliary prevention and treatment effects for preventing and treating skin damage due to the free radicals, promoting blood circulation and enhancing skin cell development can be realized by the pharmaceutical composition; tablets, capsules, granules, oral liquid or wine can be prepared from the pharmaceutical composition according to conventional processes, and the pharmaceutical composition can be applied to preparing healthcare products or additives in cosmetics.

Description

technical field [0001] The invention relates to the field of pharmaceutical preparations and / or health food processing, in particular to a pharmaceutical composition composed of proanthocyanidins and traditional Chinese medicine extracts and its use. Background technique [0002] Procyanidins (Procyanidins) are polyphenolic mixtures that widely exist in nature, and are mainly composed of catechin monomers, dimers, trimers,..., decamers, etc. Oligomeric Procyanidins (OPC´s) are known for their high efficiency, low toxicity and high bioavailability. OPC´s has a strong antioxidant capacity. Its ability to resist oxidation and scavenge free radicals in the body is 50 times that of vitamin E and 20 times that of vitamin C. It is absorbed quickly and completely. The highest blood concentration can be obtained by taking 20 mg orally. Metabolism The half-life is about 7h. There are many studies abroad on the performance of OPC´s, and they are widely used in the fields of food, bev...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/481A61P1/14A61P17/00A61P17/16A61P39/06C12G3/055C12G1/00C12C5/02A61K8/9789A61K8/49A61Q19/00A61Q19/02A61Q19/08A23L33/105A61K31/352
CPCA23V2002/00A61K8/498A61K31/352A61K36/232A61K36/236A61K36/258A61K36/481A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2800/592A61K2800/5922A61K2800/782A61Q19/00A61Q19/02A61Q19/08A23L33/105A61K8/9789A61P1/14A61P17/00A61P17/16A61P39/06C12C5/02C12G1/00C12G3/04A61K2300/00A23V2200/318A23V2200/30A23V2200/32A23V2250/21A23V2250/21166A23V2250/2124
Inventor 张奎昌张志年
Owner JIANGSU QIANYAOTANG GUOYI RES INST CO LTD
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