Organ preserving liquid

A technology of preservation solution and protective agent, applied in the field of organ preservation solution, can solve the problems of discarding, long-term preservation of organ transplant donors, and low preservation quality, and achieve the effects of good preservation, preservation of activity and function, and strong tolerance
CN109769797APending Publication Date: 2019-05-21HEFEI HUAQI BIOLOGICAL ENG CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
HEFEI HUAQI BIOLOGICAL ENG CO LTD
Publication Date
2019-05-21

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Abstract

The invention provides a method for maintaining the survival and / or function of vascular endothelial cells in the in vitro preservation process and used preserving fluid. The method and the preservingfluid are suitable for storing various organs. The in vitro liver can survive to exceed 24h during the preservation by the organ preserving liquid and in the mechanical filling process; the liver microcirculation structure is complete; no obvious damage exists; the choleresis function is good; the liver synthesis and metabolism functions are good; the in vitro preservation time of the liver is greatly prolonged; the postoperative survival rate of later-period liver transplantation patients is improved.
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Description

technical field

[0001] The present invention provides a liquid for maintaining the survival and / or function of vascular endothelial cells during in vitro preservation, and in particular provides an organ preservation liquid, which is suitable for in vitro preservation of various organs. It belongs to the field of medical equipment. Background technique

[0002] At present, organ transplantation is an irreplaceable treatment for end-stage organ disease, cancer, and acute organ failure. However, there is an extreme shortage of various organ donors in China and the world. In the usual organ transplantation process, the effect of organ preservation directly affects the success or failure of the operation and the postoperative survival of the patient. The preservation solution that has the greatest impact on organ preservation is the preservation solution that is in direct contact with the organ.

[0003] Since the advent of the University of Wisconsin solution (UW solution) in...

Claims

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