Avian influenza vaccine adjuvant and application thereof

A vaccine adjuvant, avian influenza technology, applied in vaccines, veterinary vaccines, antiviral agents, etc., to achieve the effects of improving production performance, improving economic benefits, and demonstrating broad prospects for promotion

Pending Publication Date: 2019-10-08
熊波
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Through searching, it is found that there is no report on using cefquinome sulfate as an adjuvant for avian influenza vaccine

Method used

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  • Avian influenza vaccine adjuvant and application thereof

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Experimental program
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Effect test

Embodiment 1

[0017] For a long time, avian influenza has mainly been immunized against H5N1. With the increasingly severe situation of H7N9 avian influenza prevention and control, the avian influenza vaccine was replaced by the original H5 subtype trivalent inactivated vaccine (Re-6-7-8 strain) in 2017. Become the double seedling of H5+H7. The inventor carried out a research experiment on the effect of adding cefquinome sulfate adjuvant on the immune effect of avian influenza in the vaccine.

[0018] , Experimental laying hen farm conditions

[0019] The laying hen farm is located in the eighth group of Dongfeng Village, Shiqiao Town, Shayang County, far away from crowded areas, with good natural epidemic prevention conditions and superior geographical location. The farm is a substitute breeding farm of the cooperative of Jingmen Shenyu Poultry Industry Co., Ltd. The farm is new and has no major animal diseases. The breeding capacity is 11,000 laying hens, which meets the requirements of ...

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PUM

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Abstract

The invention discloses an avian influenza vaccine adjuvant and an application thereof, which belong to the field of poultry epidemic disease control. A cefquinome sulfate adjuvant is added to the avian influenza vaccine, so that the anti-stress ability of the laying hen body is enhanced, and the mortality rate is decreased by 0.83%; the feed intake is returned to normal feed intake 4 days earlier, the peak of egg production is 15 days earlier, the peak of egg production is extended by 8 days, and the egg production is increased by 0.46%. The production performance of laying hens is significantly improved, and the demonstration and promotion of the method has broad prospects.

Description

technical field [0001] The invention belongs to the field of poultry epidemic control, and in particular relates to an adjuvant for bird flu vaccine and its application. Background technique [0002] Avian influenza is the abbreviation of avian influenza, which is divided into three categories: high pathogenicity, low pathogenicity and non-pathogenicity. represented by H7N9). Highly pathogenic avian influenza is listed as a class A animal disease by the World Organization for Animal Health because of its rapid spread, great harm, and high fatality rate in poultry, and it is listed as a class I animal disease in my country. Vaccination is the best way to prevent highly pathogenic avian influenza in poultry. Vaccines are mainly divided into three categories: attenuated live vaccines, inactivated oil emulsion vaccines, and genetically engineered vaccines. From the comprehensive consideration of practical effect, safety performance and economical practicability, the inactivate...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K39/39A61K39/145A61P31/16
CPCA61K39/39A61K39/12A61P31/16A61K2039/55511A61K2039/552C12N2760/16134
Inventor 熊波谢先林高青松廖启圣陈凤兰吕庆华陈金芝
Owner 熊波
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