194 results about "Influenza prevention" patented technology

This invention is directed to methods for treating and preventing influenza infection by inhibiting influenza virus HA maturation processes employing compounds of formula I. It is also directed to combinations for treating and preventing influenza infection comprising compounds of formula I and other agents.

A dry powder formulation for delivery to a mammal by inhalation, the formulation comprising particles comprising a lipid, a carrier, and one or more double-stranded siRNA molecules or dicer-active precursors targeted to influenza virus A method for treating or preventing influenza in a mammal comprising administering a therapeutically-effective amount of a dry powder formulation.

The present invention relates inter alia to the treatment or prevention of influenza virus infection (including subtypes influenza A virus, influenza B virus, avian strain H5N1, A / H1N1, H3N2 and / or pandemic influenza) using compounds which inhibit the activity of p59-HCK and to a method of screening for a candidate drug substance intended to prevent or treat influenza virus infection in a subject, said method comprising identifying a test substance capable of inhibiting p59-HCK activity.

The present invention relates to the intersection of the fields of immunology and protein engineering, and particularly to antigens and vaccines useful in prevention of infection by influenza virus. Provided are recombinant protein antigens, compositions, and methods for the production and use of such antigens and vaccine compositions.

The present invention provides methods for treating or preventing influenza virus infection. The methods of the present invention comprise administering to a subject in need thereof a pharmaceutical composition comprising a type II transmembrane serine protease (TTSP) inhibitor. The TTSP inhibitor preferably functions by inhibiting the proteolytic cleavage of influenza hemagglutinin (HA0) into the functional subunits HA1 and HA2. In certain embodiments, the TTSP inhibitor is an inhibitor of transmembrane protease serine S1 member 2 (TMPRSS2), such as an anti-TMPRSS2 antibody or antigen-binding fragment thereof.

The present invention relates to nucleic acid molecules comprising a double-stranded region, and nucleic acid constructs encoding therfor, that are useful for the treatment and / or prevention of influenza. In particular, the present invention relates to nucleic acid constructs encoding a double stranded RNA molecule(s) that can be used to produce transgenic poultry, for example chickens, such that they are at least less susceptible to an avian influenza infection. Also provided are nucleic acid molecules comprising a double-stranded region that can be used as a therapeutic to treat and / or prevent, for example, avian influenza in poultry.

The invention relates to a respiratory system protecting appliance, in particular to a mask capable of preventing and curing haze and influenza. The mask comprises a mask body and ear hangers, wherein the mask body covers the face, the mouth and the nose of a user; the ear hangers are connected to two short edges of the mask body and are hung on ears of the user; the mask body comprises two layers of cloth, two layers of filtering plates and a plastic nose strip; the two layers of filtering plates are arranged between the two layers of cloth; the plastic nose strip is concealed in the outer layer of cloth; the first layer of cloth is in contact with an external environment direction; the second layer of cloth is adhered to the face, the mouth and the nose of the user and is in contact with the user direction; and the filter plates comprise a filter plate which has a four-layered structure and a filter plate which has a three-layered structure and is filled with Chinese herb extracts. The mask can effectively resist PM (particulate matter) 2.5, and can also prevent influenza; a mask body can be cleaned; the filtering plates of the mask can be changed; the filtering efficiency, the breathability and the antibacterial property of the filtering plates of the mask can be obviously improved; the mask is simple in structure and comfortable to wear; and health of human bodies is facilitated.