A Cherenkov light collection device and collection method during high-performance radiotherapy

Abstract

A Cerenkov light collection device and collection method in a high-performance radiotherapy process, comprising a band-pass filter of the collected Cerenkov signal, a high-pass light-intensity imaging lens is arranged on the band-pass filter, and the high-pass light-intensity imaging lens is used for The collection device has a large amount of incoming light, and a high-energy ray shielding cabin is arranged at the back end of the band-pass filter. The top of the high-energy ray shielding cabin is provided with an image intensifier for enhancing the signal of Cherenkov light, and the output ends of the image intensifier are connected in turn. The relay lens, the photodetector and the high-voltage module are provided with a timing module at the bottom of the high-energy ray shielding cabin. The invention has the characteristics of high measurement accuracy and simple structure.

Description

technical field [0001] The invention relates to the field of optical technology, in particular to a Cherenkov light collection device and collection method during high-performance radiotherapy. Background technique [0002] Cerenkov Radiation (CR) means that when high-speed charged particles travel through a non-vacuum medium, when the particle velocity is greater than the speed of light in the medium, local polarization is generated in the direction of the motion path, and returns to the medium. Visible and near-infrared photons can be released during the equilibrium state. CR phenomenon also occurs when radiation particles enter biological tissues. Robertson et al. first applied Cerenkov radiation to the field of biomedical imaging and proposed the concept of Cerenkov Luminescence Imaging (CLI). CLI has many advantages of optical imaging, such as no radiation damage, fast imaging speed, high throughput, low price, and wide application range, especially it can be used to m...

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Problems solved by technology

[0003] However, the Cerenkov light signal generated by high-energy rays passing through biological tissues is a very weak light signal, and its intensity is about 10 -6 ~10 -9 W / cm 2 At the same time, the wavelength of Cherenkov light is mainly concentrated in the blue-violet short-wavelength region, which is very strongly absorbed by biological tissues, and only a small amount of Cerenkov light signals generated by superficial human tissues can penetrate tissues and be absorbed Therefore, the Cerenkov optical signal that can be collected for imaging is very weak, and has the characteristics of being transient and susceptible to environmental light interference. High-energy rays can damage the photosensitive element and supporting electronics of the CLI data acquisition unit, and if the CLI data acquisition unit camera is exposed to high doses of high-energy rays, it will be damaged quickly

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