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A rapid film-forming liquid band-aid containing Panax notoginseng extract

A technology of extracting liquid and band-aid, which is applied in the field of medical supplies, can solve the problems of complex preparation process of liquid band-aid, poor film-forming performance of film-forming materials, and few types of film-forming materials, so as to shorten the time of plasma recalcification and plasma recalcification The effect of shortening the time and shortening the film formation time

Active Publication Date: 2021-10-26
中山大学新华学院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main problems in the current research on liquid band-aids are that the preparation process of liquid band-aids is complicated, there are few types of film-forming materials, and the film-forming properties of film-forming materials are not good [Liu Haixia, Zhang Aijun, Zhang Lin. Research progress on liquid band-aids[J] .Chinese Medical Science, 2016,6(4):28-31]
Patent CN105363066A discloses a liquid band-aid made of PVB, PVP, ethanol, ethyl acetate, and glycerin, but the film-forming time of the obtained liquid band-aid is 2 to 3 minutes, and the film-forming time is too long, which is not conducive to the hemostasis of the wound

Method used

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  • A rapid film-forming liquid band-aid containing Panax notoginseng extract
  • A rapid film-forming liquid band-aid containing Panax notoginseng extract
  • A rapid film-forming liquid band-aid containing Panax notoginseng extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Embodiment 1 Preparation and performance evaluation of a liquid band-aid

[0037] 1. Preparation of liquid band-aid

[0038] (1) Preparation of Radix Notoginseng Extract

[0039] Weigh 30g of Panax notoginseng powder, put it in a conical flask, add 500mL of pure water, ultrasonically extract twice, each time for 15min, 3500r·min -1 Centrifuge for 15 minutes, take the supernatant to obtain the Panax notoginseng water, transfer it to a conical flask, concentrate the water extract at 80°C to 50 mL, and obtain the Panax notoginseng extract.

[0040] (2) Preparation of Liquid Band-Aids Added with Panax notoginseng Extract

[0041] S1. Weigh 25g of ethanol, 23g of butyl acetate and 26g of amyl acetate and mix evenly, weigh 8g of PVB-180S while stirring, add the mixed solution, seal (to prevent volatilization) and stir until dissolved;

[0042] S2. Add 0.5g of PVA to continue to dissolve completely, add 0.5g of castor oil and mix well;

[0043] S3. Add 1 g of Panax notogin...

Embodiment 2

[0063] Embodiment 2 Preparation and performance evaluation of a liquid band-aid

[0064] 1. Preparation of liquid band-aid

[0065] (1) Preparation of Radix Notoginseng Extract

[0066] Weigh 30g of Panax notoginseng powder, put it in a conical flask, add 500mL of pure water, ultrasonically extract twice, each time for 15min, 3500r·min -1 Centrifuge for 15 minutes, take the supernatant to obtain the Panax notoginseng water, transfer it to a conical flask, concentrate the water extract at 80°C to 50 mL, and obtain the Panax notoginseng extract.

[0067] (2) Preparation of Liquid Band-Aids Added with Panax notoginseng Extract

[0068] S1. Weigh 24g of ethanol, 25g of butyl acetate and 28g of amyl acetate and mix evenly, weigh 10g of PVB-180S and add the mixture while stirring, seal it (to prevent volatilization) and stir until dissolved;

[0069] S2. Add 1.5g of PVA to continue to dissolve completely, add 1.0g of castor oil and mix well;

[0070] S3. Add 2g of Panax notogins...

Embodiment 3

[0083] Embodiment 3 A kind of preparation of liquid band-aid and its performance evaluation

[0084] 1. Preparation of liquid band-aid

[0085] (1) Preparation of Radix Notoginseng Extract

[0086] Weigh 30g of Panax notoginseng powder, put it in a conical flask, add 500mL of pure water, ultrasonically extract twice, each time for 15min, 3500r·min -1 Centrifuge for 15 minutes, take the supernatant to obtain the Panax notoginseng water, transfer it to a conical flask, concentrate the water extract at 80°C to 50 mL, and obtain the Panax notoginseng extract.

[0087] (2) Preparation of Liquid Band-Aids Added with Panax notoginseng Extract

[0088] S1. Weigh 23g of ethanol, 21g of butyl acetate and 24g of amyl acetate and mix evenly, weigh 6g of PVB-180S while stirring, add the mixed solution, seal (to prevent volatilization) and stir until dissolved;

[0089] S2. Add 0.5g of PVA to continue dissolving completely, add 0.5g of castor oil and mix well;

[0090] S3. Add 1 g of Pa...

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Abstract

The invention discloses a rapid film-forming liquid band-aid containing a notoginseng extract. The experiment of the present invention finds that adding the Panax notoginseng extract into the formula of the liquid band-aid can significantly improve the film-forming property, greatly shorten the film-forming time, and at the same time greatly shorten the plasma recalcification time. And developed a liquid band-aid, which is prepared by mixing PVB‑180S, PVA, castor oil, amyl acetate, butyl acetate, ethanol, peppermint oil, and Panax notoginseng extract. Through the reasonable compounding of film-forming materials and the addition of Panax notoginseng extract, the prepared liquid band-aid can greatly shorten the plasma recalcification time, promote wound hemostasis, and the prepared liquid band-aid spreads rapidly, can quickly dry and form The breathable and waterproof elastic protective film instantly seals the wound surface to prevent wound infection and bacterial invasion.

Description

technical field [0001] The invention relates to the technical field of medical supplies, in particular to a rapid film-forming liquid band-aid containing a panax notoginseng extract. Background technique [0002] Band-aid is the most commonly used surgical drug in people's life. The traditional band-aid is a long adhesive plaster with gauze soaked in medicine in the middle, so as to protect the wound and temporarily stop bleeding. Traditional band-aids are suitable for superficial wounds, neat and clean wounds, little bleeding and small wounds that do not require sutures. Compared with traditional band-aids, liquid band-aids are not only more effective, waterproof, and more breathable, but also have no shape restrictions on the wound, just apply directly to the wound, non-greasy, non-stick to clothing, free movement, clean and dry. The liquid band-aid is easy to use, has a wide range of applications, and has great development value. [0003] Liquid bandage (1liquid bandage...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L26/00
CPCA61L26/0057A61L26/0061A61L26/0066A61L2300/30A61L2300/418A61L2400/04
Inventor 徐娟娟张素中王有娣郑晖晖何杺虞
Owner 中山大学新华学院
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