119 results about "Inflammation resolution" patented technology

The invention belongs to the technical field of medical instruments, and particularly relates to a dermatological acne cleaning device which comprises a shell and a medicine applying frame, the shell is an assembly carrier of the cleaning device, the shell is a vertically-through square shell, and the medicine applying frame is fixedly arranged at a through opening in the bottom face of the shell. Micro through grooves are formed in the medicine applying frame, concave-convex textures are arranged on the surface of the medicine applying frame, and the medicine applying frame is used for applying ointment for treating acne on the skin; the fixing plate is fixedly arranged on the inner wall of the shell; and the sliding frame is mounted on the bottom surface of the fixed plate through a damper. The cleaning roller with the pricking needles is used and matched with the air blowing bag to inflate air into the air inflation bag, so that the multiple sets of pricking needles in the cleaning roller can efficiently prick acne on the skin in the rolling process, meanwhile, the medicine applying frame is used for applying anti-inflammatory and antibacterial ointment in time, infection is effectively prevented, and inflammation recovery is accelerated.

The present invention discloses a polypeptide combination wound healing preparation with high permeability, specifically relating to a polypeptide combination of tripeptide-1, hexapeptide-9, and palmitoyl-modified peptide, and a new use for treating skin diseases such as wounds, ulcers, burns, scars, and keloids. While the polypeptide combination plays a significant synergistic effect in wound healing, it can effectively prevent and inhibit scar hyperplasia. In addition, the polypeptide combination wound healing preparation of the present invention utilizes the wound healing promoting activity of the composite polypeptide, and is compounded with specific penetration enhancers and antioxidants to be prepared into a gel with functions of moisturizing, promoting healing, reducing infection, and relieving pain, greatly increasing skin penetration, significantly enhancing the skin retention dose, and having significant antibacterial, anti-inflammatory, eschar-removing and muscle-generating, astringent healing, and scar hyperplasia inhibiting effects, being particularly suitable for wound healing and reducing scar residue.

The invention discloses double-crosslinking personalized hydrogel for promoting wound healing and a preparation process thereof, and relates to the technical field of biomedical materials. The hydrogel comprises sodium alginate, modified chitosan, calcium carbonate, glucolactone, acrylamide, methylene diacrylamide, ammonium persulfate and tetramethylethylenediamine, and the hydrogel can also carry drugs in the preparation process, including but not limited to drugs with the functions of diminishing inflammation, resisting bacteria, stopping bleeding and the like. The hydrogel is prepared in a double-crosslinking mode of physical crosslinking and chemical crosslinking. The hydrogel provided by the invention has the advantages of high biocompatibility, adjustable viscosity, easy replacement, adjustable water absorbability and temperature responsiveness, has a loose porous structure, has better water content, cell proliferation and migration performance, swelling performance, drug sustained release performance and the like, can effectively promote wound healing, and has a good application prospect. The method has potential application prospects in skin wound treatment and repair.

The present invention relates to anti-chemokine-like receptor 1 antibodies and therapeutic uses thereof. The present invention provides anti-CMKLR1 compounds having agonist ability for the interaction between Resolvin E1 and CMKLR1, and their use in the treatment or prevention of diseases, particularly diseases in which inflammation regression is delayed or disrupted.

The invention relates to the technical field of cosmetics, in particular to a moisturizing mask with a repairing effect and a preparation method of the moisturizing mask, and mask liquid comprises a sensitive skin repairing composition, an auxiliary effect system, a thickening system, a moisturizing system, a grease system, a buffer system and purified water. The sensitive skin repairing composition is prepared from chamomile oil, tea tree oil, a radix gentianae extract, a herba centellae extract, 4-tert-butyl cyclohexanol, butanediol, phosphatidyl ethanolamine and cardiolipin, phosphatidyl ethanolamine is modified, and the weight ratio of all the components is adjusted, so that the sensitive skin repairing composition is prepared. The traditional Chinese medicine composition has the advantages that various components in the composition are coordinated to play the optimal anti-inflammatory, anti-allergy, analgesic and repairing functions, exogenous stimulation, nerve stress response and inflammatory response are reduced, the self-protection mechanism is strengthened, the skin barrier is repaired, the oxidative stress capability is further strengthened, and the composition has more excellent high-temperature and low-temperature stability; the traditional Chinese medicine composition is natural and safe, and does not generate side effects such as dependence and drug resistance after long-term use.

The invention discloses a polysaccharide-tea polyphenol-metal compound, which is formed by dispersing a metal-tea polyphenol nano ligand in polysaccharide gel formed by covalent crosslinking of atractylodes macrocephala polysaccharide and sodium alginate, and the metal-polyphenol nano ligand is a nano complex formed by coordination of tea polyphenol and metal ions. The invention also discloses a preparation method and application thereof. The rhizoma atractylodis macrocephalae polysaccharide-sodium alginate-tea polyphenol derivative-metal composite system disclosed by the invention not only can improve the stability and release behavior of tea polyphenol in vivo, but also can regulate and control an immunometabolism microenvironment in a bone repair process, induce inflammation resolution and promote angiogenesis and bone matrix deposition, so that the bone repair effect is improved. Multiple synergistic effects of inflammation resistance, oxidation resistance, vascularization promotion and osteogenesis induction are realized, so that repair and regeneration of skull defects are remarkably accelerated, and a new intelligent immunometabolism regulation strategy is provided for repair of complex bone defects.

The utility model relates to the technical field of dressing pastes, in particular to a nano-antibacterial dressing paste for diminishing inflammation of wounds, which comprises a base layer, a tensioning mechanism and a dressing placing mechanism, the tensioning mechanism and the dressing placing mechanism are arranged on the base layer, the tensioning mechanism is used for horizontally pulling and closing the wounds, and the dressing placing mechanism is used for connecting dressings and pressurizing the wounds. Compared with the prior art, the device has the advantages that a wound can be horizontally tensioned through the tensioning mechanism composed of the first bonding piece and the second bonding piece, the wound can be pressurized through the adjustable dressing containing unit, healing of the wound is promoted, and the dressing containing unit is simple in structure and convenient to use. The dressing is adhered to the dressing placing unit, and the mounting cover is detachably connected with the fixing plate, so that the mounting cover is convenient to detach, the dressing is convenient to replace, and secondary injury to a wound in the dressing replacing process is avoided.

The invention discloses a medicinal moxa composition for preventing and treating atherosclerosis and suppurative bacterial infection co-disease. The medicinal moxa composition comprises coptis chinensis, radix rehmanniae, polygala tenuifolia, juncus effuses and moxa. The medicinal folium artemisiae argyi composition disclosed by the invention can be used for effectively preventing and treating atherosclerosis and skin suppurative bacterial infection co-diseases through a multi-target synergistic effect. The medicinal moxa composition has the core effects of clearing away heart-fire, inducing diuresis for treating stranguria and promoting blood circulation to remove meridian obstruction, and forms a complete treatment system which uses cold and warm as well as treats both symptoms and root causes by purging fire for removing toxin through coptis chinensis, clearing heat and cooling blood through radix rehmanniae, soothing nerves and promoting intelligence through polygala, inducing diuresis and conducting heat downward movement through juncus effuses and combining moxa floss for warming and dredging meridians, eliminating cold to stop pain, resisting bacteria and diminishing inflammation. By inhibiting inflammatory factors, regulating epithelial cell proliferation and reaction to oxidative stress, regulating fluid shear force, atherosclerosis and Kaposi sarcoma-related herpesvirus infection-related pathways and other mechanisms, the medicinal folium artemisiae argyi composition realizes synergistic prevention and treatment of atherosclerosis and skin infection, and provides a basis for co-disease treatment.

The utility model discloses an LED paster lamp bead used for irradiation and a light treatment device thereof, comprising a substrate, a luminescent lamp string and an electrode layer, and LED chips comprise a red light LED chip used for emitting red light and an infrared light LED chip used for emitting infrared light. According to the utility model, the luminous flux and peak values of the red light and the infrared light are reasonably proportioned, so that the mixed light finally emitted by the lamp beads can realize good anti-inflammation and pain-relieving effects on the inflammation generation part, and meanwhile, the vasodilatation and the blood circulation can be effectively promoted; a good auxiliary treatment effect is achieved on diseases such as prostatitis which occur in the body surface and urgently need to improve the blood flow characteristic, so that the treatment of the diseases through the light therapy is feasible; and meanwhile, the treatment range and the universality of the current phototherapy equipment are also expanded.

The invention discloses an atomization sterilization anti-inflammation method and device and application thereof.The method comprises the steps that an atomization assembly is provided with a containing bin, a cation exchange membrane is arranged in the containing bin and divides the containing bin into a first containing bin body and a second containing bin body, at least one first electrode is arranged in the first containing bin body, and at least one second electrode is arranged in the second containing bin body; at least one second electrode is arranged in the second containing bin, a certain amount of sodium chloride solution is poured into the first containing bin and the second containing bin, and the first electrode and the second electrode are both contained in the sodium chloride solution; the first electrode and the second electrode are connected with a power supply, the first electrode is a cathode, the second electrode is an anode, the anode electrolyzes Cl <-> in the sodium chloride solution into Cl2, and the Cl2 is dissolved in the solution to generate HCl and HClO; the atomization assembly is further provided with an atomization piece, after the first electrode and the second electrode react for a period of time, the atomization piece is connected with a power source, and the atomization piece atomizes the HClO solution contained in the second containing bin communicated with the atomization piece and then sprays the HClO solution out of the atomization assembly. And sterilization and inflammation diminishing are carried out on symptoms.

The utility model relates to the technical field of paronychia correction, in particular to a paronychia corrector, which is provided with a corrector and a dressing layer, so that in a paronychia correction process, the paronychia corrector can effectively resist bacteria and diminish inflammation for inflammation and pus generation symptoms, drain seepage, absorb the seepage through the dressing layer and correct nails, and the paronychia corrector has the advantages that the paronychia corrector is simple in structure and convenient to use. The wound does not need to be frequently cleaned, the operation is more convenient, and the correction effect is good; the device comprises a corrector, the device further comprises a dressing layer which is installed in the corrector. The corrector is used for correcting fingernails, and the dressing layer is used for antisepsis and anti-inflammation of wounds.

The utility model relates to the technical field of medical instruments, and discloses a composite support for bone tissue engineering, which comprises a shell, a plurality of fixing rings are equidistantly mounted on the outer wall of a supporting layer, a filter screen is mounted in the middle of the outer wall of each fixing ring, and a fixing block is fixedly connected to the bottom end of each fixing ring. A bottom plate is fixedly connected to the bottom end of the fixing block, a connecting pipe is fixedly connected to the middle of the top end of the bottom plate, a plurality of second medicine outlet holes are formed in the top wall of the bottom plate at equal intervals, a second cavity is formed in the middle of the fixing block and the middle of the connecting pipe, and a first cavity is formed in the middle of the shielding layer and the middle of the supporting layer. According to the utility model, the cavity I can be filled with medicines for diminishing inflammation, relieving pain, resisting infection and promoting cartilage growth, the medicines enter the connecting tube and then flow into the adjacent cavity II from the groove, and then the medicines are guided to a fracture area through the medicine outlet II, so that smooth and rapid growth of bone tissue cells can be effectively promoted, and damaged bone tissue can be repaired.

The application discloses a breathable hydrogel-based composite patch with reversible adhesion function and a preparation method thereof. The hydrogel-based composite patch is composed of a waterproof protective layer, a water absorption layer, a flow guide layer, an adhesion layer and a release paper layer in sequence, wherein the waterproof protective layer is a transparent polyurethane elastomer film, the water absorption layer is a sodium polyacrylate hydrogel, the flow guide layer is a non-woven fabric, the adhesion layer is dopamine and 7-carboxymethoxy-4-methyl coumarin double-graft modified chitosan, and a medicine component for relieving inflammation and pain and promoting blood circulation to remove blood stasis is loaded in the water absorption layer. The porous waterproof protective layer and the water absorption layer, and the water absorption layer and the flow guide layer are all bonded by using an acrylate adhesive; the flow guide layer and the release paper are connected by the adhesion capacity of the adhesion layer. The adhesion layer has reversible adhesion function in response to ultraviolet light, and the product has good ventilation capacity through selection of raw materials and structural design.

The invention discloses a bacteriostatic and anti-inflammatory polypeptide extract and application thereof in a Yao bath. The polypeptide extract is extracted from rhizomes of Coptis chinensis (Coptis chinensis Franch.), and is obtained through extraction with a phosphate buffer solution, ultrafiltration and gel chromatography purification, and the polypeptide is as shown in SEQ ID No: 1. Experiments show that the polypeptide extract has significant bacteriostatic activity on pathogenic bacteria such as escherichia coli, shows a dose-dependent anti-inflammatory effect in an RAW264.7 cell model, can effectively inhibit NO release, and has a cell survival rate of 92% or more and excellent biological safety. The polypeptide extract is applied to a Yao bath preparation, O / W type emulsion is prepared, 10 volunteers try on the Yao bath preparation, the improvement rate on mild skin inflammation symptoms (such as red and swollen and pruritus) reaches 87%, and anaphylactic reaction is avoided. The polypeptide extract is simple in preparation process and high in activity, and has a wide application prospect in the fields of cosmetics and medicines.

The invention provides a formula for centipede stings and bites and a preparation method thereof. Comprising the following raw materials: acidic liquid, nail powder and an analgesic and anti-inflammatory synergist, the acidic liquid is white vinegar or fruit vinegar; the formula provided by the invention is scientific and reasonable, all the components have a synergistic effect, the effect is remarkable, the white vinegar can directly neutralize main acid toxins in centipede venom, the main component of the nail powder is keratin, and the keratin can be hydrolyzed and swelled to a certain degree in an acid environment to form a protective layer, so that external stimulation can be isolated, and the nail powder can be effectively prevented from being damaged. The added analgesic and anti-inflammatory synergists such as menthol and borneol have natural cooling, paralysis and transdermal promotion effects and can instantly act on nerve endings to generate strong cold feeling so as to transfer and cover pain signals, and permeation of other effective components is promoted; meanwhile, the components also have certain anti-inflammatory characteristics and can synergistically inhibit release of local inflammatory mediators, so that the fading of red and swollen is accelerated.

The invention discloses a preparation method and application of a kaolin-graphene quantum dot composite material, and belongs to the technical field of hemostatic materials. The preparation method comprises the following steps: by taking hemostasis, bacteriostasis and anti-inflammatory efficiency as indexes, modifying graphene quantum dots to obtain a modified graphene quantum dot material with excellent comprehensive performance, and then performing chemical crosslinking on the modified graphene quantum dot material and kaolin to obtain the kaolin-graphene quantum dot composite material; the obtained composite material is loaded on a base material gauze through dipping / spraying, and the finally prepared composite hemostatic device not only can efficiently stop bleeding and effectively control the kaolin falling problem, but also has the characteristics of small blood suction amount, inflammation diminishing and bacterium resistance.

The present application relates to a kind of skin grafting materials and its preparation and use method, which is composed of carrier sheet, anvil sheet and repair liquid, without skin adhesive;When using, cut skin dermis layer is attached to anvil sheet, put into medical leather rolling machine, and cut into microskin grafting;Spray repair liquid on the cut microskin grafting, transfer to carrier sheet, paste in the place to be grafted, separate aluminum foil and take down, wrap with gauze.The skin grafting material provided by the present application can reduce the damage to new granulation when removing skin grafting material, has the effects of antibacterial and anti-inflammatory, promoting repair and healing, promoting cell proliferation, providing scaffold for cell crawling, hemostasis, absorbing exudate, reducing scar formation and pigmentation, etc., can effectively accelerate epithelialization in skin grafting area;The effect after recovery is good, can be used for burn and scald, mechanical trauma, diabetic foot and other wounds, and has wide application prospect.

The invention discloses a preparation method of a bionic magnetic nano-motor mixed and wrapped by a neutrophile granulocyte membrane and a stem cell exosome. The bionic magnetic nano-motor comprises the neutrophile granulocyte membrane, the stem cell exosome, a polylactic acid-glycolic acid copolymer and an anti-inflammatory drug. According to the method, a layer of polylactic acid-glycolic acid copolymer is wrapped outside magnetic ferroferric oxide nanoparticles and an anti-inflammatory drug by utilizing an ultrasonic emulsification method, and finally the polylactic acid-glycolic acid copolymer is wrapped by utilizing a neutrophile granulocyte membrane and a stem cell exosome, so that the bionic magnetic nano motor is obtained, and the motor has good biocompatibility. Meanwhile, the motor has an immune escape function and can resist phagocytosis of macrophages in blood. And under the control of an external alternating magnetic field, the medicine can accurately reach a spinal cord injury part, and the effects of inflammation inhibition and neuron recovery can be achieved under the mixed action of neutrophile granulocyte membranes, stem cell exosomes and anti-inflammatory drugs.

The application discloses an acne-removing and inflammation-reducing facial mask and a preparation method thereof. The facial mask contains drug-loaded hyaluronic acid polypeptide nanoparticle emulsion, glycerol and nicotinamide. The drug-loaded hyaluronic acid polypeptide nanoparticle emulsion is an oil-in-water pickering emulsion with drug-loaded hyaluronic acid polypeptide nanoparticles as an emulsifier and an oil phase containing tea tree essential oil. The drug-loaded hyaluronic acid polypeptide nanoparticles are nanoparticles self-assembled from dopamine-modified hyaluronic acid and antibacterial peptides in a solution containing drugs. The nanoparticles have hyaluronidase responsiveness. When there are many acne pathogenic bacteria in the skin, the release of the content antibacterial peptides and cryptotanshinone can be accelerated, the stimulation of cryptotanshinone on the skin can be reduced, and a long-acting and slow-release effect can be achieved.

This invention discloses a spray composition, its preparation method, an oral care device, and its application, belonging to the field of biomedical technology. The composition is a synergistic compound of a herbal enzyme solution prepared by a "cell wall breaking-enzymatic hydrolysis-fermentation" process and a lyophilized stem cell exosome powder. The herbal enzyme solution contains berberine ≥1.2 mg / mL and baicalin ≥1.0 mg / mL, exhibiting high anti-inflammatory (IL-1β inhibition rate ≥55%) and deodorizing (VSC decomposition rate ≥88%) effects. The lyophilized exosome powder is rich in VEGF (≥50 pg / mg protein) and TGF-β1 (≥30 pg / mg protein), promoting gingival repair. The stability and delivery challenges of exosomes are solved through "lyophilization and reconstitution + ultrasonic atomization," resulting in atomized particles of 1–10 μm (D50 = 1–5 μm). Experimental results show that the gingivitis redness and swelling subsides in ≥90% of cases, the gingival recession thickness increases by 0.4–0.6 mm in 8 weeks, fresh breath is maintained for 4–6 hours, and the healing cycle of oral ulcers is shortened by 40%–50%, achieving a synergistic effect of "immediate antibacterial and anti-inflammatory treatment + long-term tissue repair".

The utility model discloses an anti-inflammation nursing device for the urology department, and relates to the technical field of the urology department, the anti-inflammation nursing device for the urology department comprises a fumigation chair, and T-shaped guide holes are formed in two armrests of the fumigation chair in the length direction of the armrests; a first T-shaped guide block slides in one of the T-shaped guide holes in a friction mode, and a transverse plate which is parallel to a cushion on the fumigation chair and located below the cushion is fixed to the first T-shaped guide block through a first vertical plate. A second T-shaped guide block is arranged in the other T-shaped guide hole in a friction sliding mode, a longitudinal plate perpendicular to the transverse plate is arranged on the fumigation chair in a sliding mode, a second vertical plate is fixed to the second T-shaped guide block, and the second vertical plate is rotationally matched with the side face of the end of the longitudinal plate through an inclined plate; sliding grooves are formed in the transverse plate and the longitudinal plate in the length direction of the transverse plate and the longitudinal plate. Fumigation is guided through the smoke outlet pipe, the fumigated smoke is accurately fumigated to the affected part of the patient, waste of the smoke is avoided, and the anti-inflammation nursing effect is better.

The application provides a luffa bath liquid with antibacterial and anti-inflammatory functions, which comprises the following components by weight: 10-18 parts of a ketone compound extract as a first component, 22-35 parts of a lignan compound extract as a second component, 2-5 parts of a triterpene compound as a third component, and 20-30 parts of butyl avocadoate as a fourth component. The luffa bath liquid has an effect of inhibiting the respiratory burst of neutrophils to a certain extent, and can prevent the occurrence of allergic diseases and some cardiovascular and cerebrovascular diseases. The effect is obtained by combining the first component, the second component and the third component.

The invention discloses a hemostatic PW4-FIDD-SUP as well as a preparation method and application thereof, and belongs to the technical field of medicines. According to the preparation method, different phase-state preparations are prepared by performing different phase-state resolution on the wine-processed radix scutellariae and fructus gardeniae matched water decoction, and the difference condition among different preparations is determined through physical property detection, protein and total sugar content detection and component analysis. The invention also determines that the internal dialysis fluid-supernatant (PW4-FIDD-SUP) of the wine-processed radix scutellariae and fructus gardeniae matched water decoction has a remarkable effect in the aspects of regulating and controlling body functions and preventing and treating gastrorrhagia, and the PW4-FIDD-SUP has the effects of diminishing inflammation and relieving pain. The research result of the invention provides a new strategy for the development of a novel preparation of the fructus gardeniae stir-fried with wine radix scutellariae, and provides a theoretical basis for the research of pharmacodynamic substances of the fructus gardeniae stir-fried with wine radix scutellariae.

1. Name of the product in this design: LED therapeutic device. 2. Purpose of this design: This design is used to assist in anti-inflammatory treatment, accelerate wound healing, and as an adjunct treatment for acne. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

1. Name of the designed product: packaging box (Deji Tang - far infrared anti-inflammatory analgesic patch 2). 2. Use of the designed product: for packaging products. 3. Design points of the designed product: in the combination of shape, pattern and color. 4. Picture or photo that best indicates the design points: design 1 front view. 5. The design for which protection is sought includes color. 6. Design 1 is designated as the basic design.

The invention discloses a hemostatic and anti-inflammatory dressing patch, which comprises a base layer, a colloid dressing layer and release paper, and is characterized in that the colloid dressing layer is composed of specific active ingredients and colloid dressing. The active component is prepared from asiaticoside, panax notoginseng saponins, ellagic acid, gallic acid and paeonol according to a specific weight part ratio. The core of the preparation method is as follows: aiming at active ingredients with different properties, firstly performing differential pretreatment, then mixing with a gel matrix composed of carbomer-940, polyvinylpyrrolidone K90 and the like through a step-by-step drug loading process, and finally performing cross-linking curing through medium-wave infrared preheating and ultraviolet irradiation to form a stable interpenetrating network hydrogel structure. Through component compounding and process innovation, the technical problems that multiple active components are poor in compatibility, prone to inactivation and uncontrollable in release in a matrix are effectively solved, the product has the multiple synergistic effects of rapid hemostasis, powerful anti-inflammation, lasting analgesia and healing promotion, and the performance of the product is remarkably superior to that of an existing product.

The present invention belongs to the field of medicine and specifically discloses a heat-sensing microemulsion gel preparation and a preparation process thereof. The preparation comprises a microemulsion, a hydrogel matrix, and a drug-containing fluid extract, which are stirred and mixed. The present invention achieves the stable presence of an oily component in the aqueous gel matrix by preparing the microemulsion, and controls the particle size of the microemulsion to be below 50 nm through the process, thereby further improving the stability of the entire gel system. While resolving the poor compatibility between the oil phase and the aqueous phase, and the unstable and easily delaminated system, the present invention also ensures that the heat sensation is generated quickly and lasts for a long time. Furthermore, the addition of a heat-sensing agent can accelerate microcirculation and significantly improve the local absorption efficiency of the drug-containing fluid extract having the efficacy of promoting blood circulation, removing blood stasis, reducing inflammation, relieving pain, and healing wounds, thereby ensuring that the prepared heat-sensing microemulsion gel has good heat-generating and analgesic efficacy. Furthermore, the heat-sensing microemulsion gel prepared by the method has the characteristics of a refreshing and translucent texture, being non-greasy, and having a good skin feel.

1. The name of the design product: microwave therapeutic instrument (internal and external hemorrhoid treatment). 2. The use of the design product: medical chair for microwave treatment of anorectal diseases, with physiotherapy functions of anti-inflammatory analgesic and promoting blood circulation. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

The invention discloses a viscous tussah silk gland protein gel dressing with microenvironment response and antibacterial property and a preparation method thereof, N-isopropylacrylamide is polymerized to form poly-N-isopropylacrylamide through in-situ free radical polymerization, and meanwhile, the poly-N-isopropylacrylamide, tussah silk gland protein and sodium alginate form gel in a stable form through intermolecular interaction; on one hand, the gel dressing has good temperature-sensitive response performance and realizes intelligent drug controlled release, and on the other hand, the hydrogel can be well adhered to the skin surface, can promote growth and reproduction of human skin fibroblasts, shows good biocompatibility and mechanical properties, has better adhesion stress than commercial wound dressings, and has good application prospects. An application basis is provided for the application of the sodium alginate group in the intelligent medicine controlled release medical wound dressing; finally, the gel dressing is loaded with a natural antibacterial agent and Chinese herbal medicines, and has the effects of resisting bacteria, diminishing inflammation and the like at the affected part; therefore, the gel dressing disclosed by the invention has great application potential in the medical field.

The present invention discloses a fullerol-deep eutectic solvent-agarose gel with electric-driven controlled drug release function and a preparation method thereof. The components involved in the system include fullerol (TEGs-C 60 ), low eutectic solvent (choline chloride-malic acid or lactic acid or citric acid), agarose and loaded anti-inflammatory drugs; among them, the low eutectic solvent is used as a crosslinker and conductive medium of the gel, and TEGs-C with a large cavity 60 The gel is immobilized on the surface of the gel. The preparation process of the gel is simple and easy to scale up. It is particularly suitable as a portable drug carrier for anti-inflammatory and electrical stimulation therapy of difficult-to-heal wounds in special populations (such as diabetic patients). In addition, its conductivity, stability, mechanical strength and other indicators are good, and it also has the effect of inhibiting the growth of microorganisms. 60 The free radical scavenging effect it possesses can also cooperate with other components to achieve a comprehensive therapeutic effect on local lesions.