527 results about "Inflammation resolution" patented technology

The invention discloses a medicinal composition for treating skin injury and ulcer diseases, and belongs to the field of Chinese medicament. The medicinal composition consists of collagen and Chinesemedicaments for fighting bacterium, diminishing inflammation, removing putrefaction and promoting tissue regeneration such as angelica, Szechuan lovage rhizome, salvia root and the like which are prepared into a plurality of dosage forms by matching the prior art. The technology overcomes the defects that the prior preparations for the trauma department have extremely slow response, longer treatment course, adhesion with the skin, influence on scab cicatrization and the like, and has quick and remarkable treatment effect on various skin diabrosis diseases such as mechanical wound, burn / scald,bedsore, chronic leg ulcer, diabetic foot or cancerous ulcer and the like.

The invention relates to a medical biological dressing, particularly to a medical biological scar-inhibiting rhytidectomy dressing and a preparation method thereof. The dressing is composed of modified chitosan, silicone, glycerol, camellia oil, olive oil, almond oil, an aloe extracting solution, active growth factors, hyaluronic acid and a ginger extracting solution. With adoption of the formula, skin regeneration organs are retained and activated furthest, and a good foundation is laid for wound repair. The formula is reasonable and scientific and has the efficacies of clearing away heat and toxic materials, removing slough and promoting growth of tissue regeneration, promoting blood circulation and removing blood stasis, and relieving swelling and pain on scars, has an impressive preliminary therapeutic effect on scars of skin epidermis bruise, trauma, traumatism, burning, scald, and post-operation wound, has the advantages of high efficacy, rapid pain relieving, low possibility of infection, simple preparation method, and good convenience in usage and popularization, and is used for burning, scald, trauma, bruise, traumatism, post-operation wound hemostasis, inflammation diminishing, pain relieving, wound infection prevention, scar inhibition, skin wrinkle and crack prevention, and wrinkle inhibition.

The present invention provides a burn and scald liquid and a burn and scald ointment. The burn and scald liquid provides good effects for treating first degree burn and scald, and second degree burn and scald. The burn and scald ointment provides significant effects for treating purulent infection, ulceration, healing requiring a long time, difficult growth of new muscle, burn and scald, especially the deep second degree burn and scald and three degree burn and scald. Compared to external application method in the western medicine, infrared therapeutic equipment, frequency spectrum therapeutic equipment, electronic therapeutic equipment, anion generator, and the like in the prior art, the burn and scald liquid and the burn and scald ointment provided by the present invention has characteristics of heat clearing and detoxification, inflammatory eliminating and analgesia, slough transforming and muscle growing, strong anti-infection property, rapid improvement of wound healing. With adopting the burn and scald liquid and the burn and scald ointment, the patients with slight and scald and without skin exfoliating can be healed in 3-7 days, the patients with deep second degree burn can be healed in 15-20 days, the patients with deep burn can be healed in about 2 months. In addition, after healing, the skin of the patient is smooth, the pores are revived, no scar is remained, and the significant healing effect is provided.

The invention relates to liquid band-aid and a preparation technology thereof. The liquid band-aid is prepared from the following components in percentage by weight: 5%-20% of a film-forming agent, 4%-12% of a softening agent, 0.1-8% of an antibacterial agent, 3%-10% of a haemostatic and analgetic agent, 1%-5% of a healing agent, and 53%-83% of a solvent. The preparation technology comprises the following steps: adding 5%-20% of the film-forming agent and 53-83% of the solvent into a reactor, and soaking for 1-2 h; heating to 65 DEG C to 70 DEG C so that the film-forming agent completely swells; and sequentially adding the softening agent, the antibacterial agent, the haemostatic and analgetic agent and the healing agent into the reactor under stirring, and uniformly stirring to prepare the liquid band-aid. The liquid band-aid overcomes the defects that the traditional band-aid is not attractive, and the wound can not move freely. The liquid band-aid has the characteristics of being rapid in hemostatic effect, strong in inflammation diminishing and bacteria killing properties, and low in cost, and the wound part can move freely.

The invention discloses a multifunctional temperature-sensitive gel composite dressing for wound healing and preparation and usage thereof. The dressing comprises a quaternized chitosan derivative and an aldehyde-terminated temperature-sensitive polymer, a mass ratio of the two components is 1:15-1:25, wherein a molecular weight of chitosan for preparing quaternized chitosan is between 100 thousands and 1000 thousands, the degree of deacetylation is above 90%, and the degree of quaternized substitution is 10%-45%. The dressing is a thick liquid easy to apply to a wound at room temperature, and after it is applied to the wound, a gel film coating may form within 1 min. The temperature-sensitive gel composite dressing prepared based on the invention has autonomous antibacterial and anti-inflammatory effects and good film-forming stability, may also provide a wet environment and a sustained drug release function and is useful for treating and healing wounds such as diabetic foot ulcers.

The invention provides a titanium dioxide composite material and a preparation method and application thereof. The titanium dioxide composite material at least comprises titanium dioxide and fluorine or carbon doped on titanium dioxide, or fluorine and carbon co-doped on titanium dioxide. The titanium dioxide composite material has good biocompatibility, has antisepsis and anti-inflammation effects as well as an effect of promoting bone cell proliferation, has strong applicability, and also can be used as a photocatalytic material.

An inflammation-relieving staltic medicine for first aid and surgical operation is proportionally prepared from chlorhexidine, chitosan, notoginseng, beauty berry and polyurethane as matrix.

The invention discloses a compound traditional Chinese medicine for diminishing inflammation, checking diarrhea and relieving pain. The compound traditional Chinese medicine consists of the following active pharmaceutical ingredients by weight:10-14 grams of poria, 8-12 grams of rhizoma atractylodis macrocephalae, 10-14 grams of semen dolichoris album, 8-12 grams of dioscorea opposita, 6-10 grams of myristica fragrans, 10-14 grams of cortex magnoliae officinalis, 8-12 grams of rhizoma atractylodis, 8-12 grams of endoconcha sepiae, 6-10 grams of pericarpium citri reticulatae, 4-8 grams of pinellia tuber, 8-12 grams of inula britannica, 8-12 grams of reddle, 8-12 grams of endothelium corneum gigeriae galli, 8-12 grams of fructus amomi, 8-12 grams of fructus crataegi, 8-12 grams of fructus hordei germinatus, 8-12 grams of semen raphani, 6-10 grams of massa medicata fermentata, 8-12 grams of root of pilose asiabell, 8-12 grams of ixeris denticulata, 8-12 grams of anemone chinensis, 8-12 grams of herba taraxaci, 6-10 grams of fructus litseae, 4-8 grams of lignum dalbergiae odoriferae, 4-8 grams of cortex fraxini, 4-8 grams of pericarpium granati, 8-12 grams of halloysit, 4-8 grams of citrus medica linn, 4-8 grams of fructus citri sarcodactylis, 6-10 grams of corydalis turtschaninovii bess and 6-10 grams of fructus meliae toosendan. The compound traditional Chinese medicine has obvious effects in treating chronic gastritis, dyspepsia, diarrhea and abdominal pain. The compound traditional Chinese medicine has the advantages of short treatment time, good treatment effect, no side effect and the like.

The invention discloses a preparation method of chitosan / acetalized poval medical dressing, and in particular relates to a preparation technology of poval sponge. A dressing with bioactivity can be prepared by adding a poval / chitosan mixed solution in poval acetalation reaction. The chitosan / acetalized poval medical dressing has biocompatibility,the effects of inflammation, blood stopping, wound surface healing promotion, good breathability, water absorbability and tensile strength; in addition, proved by the search on toxic effect on mouse fibroblast cells, the chitosan / acetalized poval medical dressing has no obvious toxicity to the mouse fibroblast cells, but has the effect of promoting the growth of the mouse fibroblast cells.

The invention provides an externally applied medicament for treating tinea of hands and feet, consisting of three parts of powders A, electuary B and spray C, and the main ingredients comprise lightyellow sophora root, giant knotweed rhizome, dark plum fruit, salicylic acid, ketoconazole and the like, thereby having the effects of clearing heat, removing toxin, sterilization and anti-inflammation. The medicament is different from the previous simple treatment proposals for treating the tinea of hands and feet, the powers A is firstly used for rapidly killing pathogens at the skin surface, changing the infected lesion skin tissue structure of the surface, leading the structure to be loose and forming a smooth channel which is conductive to the penetration of the medicament, then the electuary B is used under the premise of the channel for dredging the penetration of the medicament, thereby rapidly and thoroughly killing the pathogens in skin, the spray C is used for powerful sterilization, keeping a clean environment for the skin and achieving the effect of no recurrence. The medicament carries out multi-level three-dimensional treatment, simultaneously realizes the treatment of external and internal diseases, combines the prevention with the treatment and simultaneously treats both principal and secondary aspect of disease, thereby realizing the special treatment method and reliable efficacy.

A functional dressing (film) comprises an edge remaining film 1 and a fixed pasting film 2 which are convenient to separate from each other, wherein a functional pad 3 is arranged between the edge remaining film 1 and the fixed pasting film 2, a protective film 4 is arranged on the face, with the back towards the functional pad, of the fixed pasting film, and a plurality of layers of annular adhesive tape or adhesive tape shaped like a Chinese character 'hui' is arranged on the fixed pasting film. Thus, on the one hand, the binding area of the fixed pasting film and the skin is reduced, and on the other hand, sweat can volatilize through reserved gap; due to the fact that a functional layer and a moisture-preserving layer are arranged in the functional pad, medicine ingredients in the functional layer and the moisture-preserving layer act on wounds and peripheral tissue, and the functional dressing (film) has the functions of stopping bleeding, resisting and preventing bacteria, diminishing inflammation, easing pain, promoting healing, reducing scar formation and accelerating local blood circulation.

The invention relates to a medicinal preparation for treatment of acne (pimples), folliculitis and pustular herpes and a preparation method thereof, and the medicine belongs to a Chinese medicinal tincture for treatment of inflammatory diseases of facial skin. The medicine provided in the invention is prepared from 87g-28g of paris polyphylla, 16g-6g of safflower, 12g-7g of Salvia Miltiorrhiza, 16g-8g of honeysuckle, 17g-6g of sophora flavescens, 12g-4g of Chinese honeylocust spines and 1000ml of 50%-80%V / V alcohol by means of a combined process of alcohol extraction and high-temperature cooking water extraction. The medicine can comprehensively adjust the metabolism of skin cells on facial skin, has strong effects of bacterium resisting, inflammation diminishing, blood circulation promoting and scar removing. With significant effects, the medicine generally takes effect in 3 days, and has the advantages of no toxic or side effect after long-term use, wide medicine sources, simple preparation, and easy promotion.

The invention discloses a preparation method of a medical hemostatic sponge material. The preparation method comprises the following steps: weighting all components in parts by weight; putting all the components into a stirrer and stirring at a speed of 90-100 rpm for 80-90 min; pouring the obtained mixed liquor into a film forming device, and putting into a vacuum freeze drying machine for freeze drying for 15-35 hours, so as to obtain an antibacterial anti-inflammation medical sponge. The medical hemostatic sponge material prepared by the method provided by the invention is excellent in diminishing inflammation, stopping bleeding, resisting bacterium, and resisting edema, is good in biocompatibility and mechanical property, has a strong recuperability to damaged tissues, can prevent rebleeding and eliminate virus potential hazards due to gelatin and animal collagen, so that the use safety is greatly improved.

The invention discloses a functional patch and a preparation method and applications thereof. The functional patch comprises a support layer and a functional layer. The support layer is composed of a non-degradable polymer mesh material. The functional layer is composed of a particle attached cellulose membrane. The cellulose membrane and particles are composed of polymers and loads. The cellulose membrane is prepared by an electro-spinning method, and the particles are prepared by an electro-spraying method. Compared with the conventional patches, the patch has the functions of preventing bacteria, eliminating inflammation, reliving pains, preventing adhesion, and promoting wound healing, and can be applied to the fields such as scaffold for tissue engineering, drug-delivery carriers, wound dressing, and the like.

The invention discloses an extracting process for a club fungi polysaccharide. The extracting process comprises the following steps: carrying out the pretreatment of raw materials, carrying out the hot water leaching, ultrasonic extraction or microwave extraction, and storing the extract after concentration, alcohol deposition, centrifugation and drying, wherein the hot water leaching method has moderate conditions and simple operation; and the ultrasonic extraction method and the microwave extraction method can save time and improve the extraction efficiency. The extracted club fungi polysaccharide has an inhibition rate of 70 percent for little white rat S-180 and Ehrlich carcinoma, and has the functions of improving the immunity, diminishing inflammation, easing pain, and the like.

The invention relates to a rapid haemostat using mipor starch with a high specific surface area as a main raw material and a preparation process thereof. The rapid haemostat capable of being absorbed by a human body is prepared by using the mipor starch with the high specific surface area as the raw material and adding growth factors stimulating the rapid healing of a wound and an antimicrobial with diminish inflammation and infection-resistant effects. The haemostat not only can more rapidly and effectively arrest bleeding, but also can effectively accelerate the healing, the diminish inflammation and the infection resistance of the wound.

The present invention is one kind of dermatosis treating medicine and its preparation process. The dermatosis treating medicine is prepared with Chinese goldthread, phellodendron bark, climbing groundsel, gromwell, aloe, vaseline, glycerin and sesame oil in certain proportion. The medicine of the present invention has the functions of diminishing inflammation, relieving pain, drying wetness, astringing, promoting granulation, etc. The medicine has obvious curative effect on baby's napkin area dermatitis, bedsore and scalds,

The invention discloses a bleeding-stopping pain-relieving dressing and a preparation method thereof. The bleeding-stopping pain-relieving dressing is in the shape of a powder or a composite membrane. The composite-membrane-shaped bleeding-stopping pain-relieving dressing comprises a medicine storage layer and a basic layer which are bonded together via a binder. The provided dressing is applicable to medicinal rapid bleeding stopping, bacteria resisting, inflammation diminishing, wound healing promoting and other aspects.

Sub-100 micron multimodal nanoparticles have four main components: 1) a target element (peptides, lipids, antibodies, small molecules, etc.) that can selectively bind to cells, tissues, or organs of the body; 2) a diagnostic agent such as a fluorophore or NMR contrast agent that allows visualization of nanoparticles at the site of delivery and / or a therapeutic or prophylactic agent; 3) an outside “stealth” layer that allows the particles to evade recognition by immune system components and increase particle circulation half-life; and 4) a biodegradable polymeric material, forming an inner core which can carry therapeutics and release the payloads at a sustained rate after systemic, intraperitoneal, or mucosal administration. These particles possess excellent stability, high loading efficiency, multiple agent encapsulation, targeting and imaging. They are targeted to sites of, or associated with, inflammation caused by a disease, disorder; trauma, chemotherapy or radiation.

The invention relates to a non-steroidal anti-inflammatory drug with nitrogen oxide donor and a method for preparing same, which can be used to eliminate inflammation, relieve fever and stop pain, and can decrease the frequently seen side effect thereof on the gastrointestinal tract. The structure of which is A-O(X)-CO-O(y)-B-ONO2,wherein, A is the non-steroidal anti-inflammatory group; B is the connection group, when x=0, y=1; when x=1 then y=0. The the non-steroidal anti-inflammatory groups includes aspirin, diclofenac, indometacin, lumiracoxib, brufen, ketoprofen, naproxen, piroxicam, and meloxicam. The preparation process are that the bromhydrin (or hydroxybenzene) reacts with silver nitrate into hydroxy nitrate, then reacts with bromo acid into the connection group of nitrogen oxide donor, then connects with the non-steroidal anti-inflammatory drug; or the non-steroidal anti-inflammatory drug condensates with bromo acid into a bromide intermediate, then reacts with silver nitrate into the non-steroidal anti-inflammatory drug with nitrogen oxide donor.

The invention discloses a non-removing antibacterial skin suture for cosmetic surgery. The suture comprises a suture body. The suture is characterized in that: the suture body is made of human absorbable material; and when the suture body is made, a medicament with an inflammation diminishing effect and / or a medicament with a pain easing effect are added, and the added medicament is 0.01 to 10 percent based on the weight of the suture body. The suture for suturing the wound eliminates infection, avoids frequently changing the medicament, can reduce suture knot response and reduce scars, and can be automatically absorbed in tissues; the suture can promote wound healing, prevent infection and reduce scars; a large amount of clinical application proves that the suture has a satisfying effect, reduces the subsequent visit times of a patient, and avoids the pain of removing the suture; and the suture has a sterilization effect, realizes sterilization in an incision, and has a better antibacterial effect.

The invention relates to the technical field of medical glue and in particular relates to chitosan biological medical glue for promoting human epidermal growth and a preparation method of the biological medical glue. The chitosan biological medical glue comprises the following raw materials in parts by weight: 10-100g of modified chitosan, 4-20000mg of nano-silver, 1-80g of human-like collagen, 10-400g of glycerol, 0.0001-0.1g of epidermal growth factor, 0.1-200g of viscosity regulator, 0.5-4g of cross-linking agent and the balance of purified water. Main and auxiliary materials take a synergistic effect to form a drug delivering system with a slow release function, thereby improving the availability of active substances; the chitosan biological medical glue is attached close to the uneven wound surface, but the chitosan biological medical glue does not stick to the uneven wound surface. The chitosan biological medical glue is excellent in biocompatibility, strong in antisepsis and anti-inflammation, free of local stimulation and systemic adverse reaction, colorless and transparent, conducive to wound observation, capable of quickly promoting the repair of the wound surface, suppressing and reducing the generation of scar and widely applicable to the treatment of infected wound, operative incisions, all burns, scalds and wounds.

The invention discloses an application of piperlongumine in the preparation of anti-bacterial and anti-inflammatory drugs. By performing RNA-seq transcriptome analysis for the cells of people infectedwith bacteria, a list of drug candidates with functions of antisepsis and anti-inflammation can be obtained on account of analysis methods of co-expression pathway and drug gene aggregation, whereinthe list comprises a plurality of marketed drugs with anti-bacterial and anti-inflammatory effects, the piperlongumine not discovered to have anti-bacterial and anti-inflammatory effects is right in the list. Therefore, the piperlongumine can be used in the preparation of anti-bacterial and anti-inflammatory drugs.

The invention discloses a preparation method for a polylactic acid nanofiber scaffold functionally modified by two-dimensional nanometer black phosphorus, and aim to provide a preparation method for amultifunctional modified polylactic acid scaffold. The preparation method is characterized in that a black phosphorus nanosheet is taken as a medicine carrier to load an anti-inflammatory medicine, i.e., ibuprofen, a natural high polymer material, i.e., sodium alginate, is taken as a coating material, and through a crosslinking function of strontium ions, a medicine-carrying microsphere is obtained; an electrostatic interaction is used for evenly doping a sodium alginate medicine-carrying microsphere into a modified polylactic acid basis material which is subjected to ammonolysis and modification by branched polyethyleneimine and is rich in an active amino group; and through freezing phase separation, the modified polylactic acid scaffold with a reticular nanometer fiber structure is obtained. The preparation method has the characteristics that the prepared modified polylactic acid nanofiber scaffold embedded with the medicine-carrying microsphere is a multifunctional system with thefunctions of performing photothermal therapy, accelerating bone growth, resisting bacteria, diminishing inflammation and intelligently releasing medicines, and the polylactic acid nanofiber scaffold is an ideal bone repairing material.

The invention relates to povidone iodine effervescent tablets with anti-microbial, skin-care and anti-inflammation functions and a production process of the povidone iodine effervescent tablets. The effervescent tablets comprise 10%-15% of povidone iodine, 51%-80% of an effervescent disintegrating agent, 1%-5.5% of a tablet disintegrating agent, 1.3%-5% of a compound polymer synergist, 0.01%-0.1% of zinc oxide, 0.05%-0.5% of dextrin, 0.5%-5% of polyethylene oxide, 0.1%-5% of a lubricant and the balance of filler. According to the effervescent tablets, a medicine integrating anti-microbial, anti-inflammation and skin-care functions and having complete functions is developed by carefully studying the function mechanism of medicines after multiple experiments, the anti-inflammation function is realized in the disinfection process, and the medicine administration step is simplified in the medical process. Besides, pain of a patient in the medicine use process is relieved, and detection shows that the irritation of the effervescent tablets in the formula is extremely small and is much lower than that of like products. The preparation process is simple and convenient to operate, the equipment is simple, and the product is convenient to use, transport and carry and suitable for industrial large-scale popularization and use.

The invention relates to a functional dressing for inhibiting scar hyperplasia and a preparation method thereof. The dressing comprises a fixed layer, an activated carbon fiber, a composite silica gel and a stripping layer, wherein the composite silica gel comprises the following components: chitosan, fucoidin, silicone, gels and surfactants; and the activated carbon fiber is arranged on the fixed layer, and the composite silica gel is arranged on the activated carbon fiber. The silica gel functional dressing disclosed by the invention can play roles in resisting bacteria and diminishing inflammation, stopping bleeding and relieving pain, adsorbing seepage and the like in the beginning of wound formation; and meanwhile, by adopting the silica gel functional dressing, a warm and humid environment beneficial to wound healing can also be formed, the wound healing can be accelerated, fibrous tissue proliferation can also be inhibited in a wound healing process, and the generation of scars can be resisted from the source.

The invention relates to the quality control field of traditional Chinese medicine, in particular to a quality control method of a compound anti-inflammatory and cholagogic preparation and applications thereof. The method comprises the steps of: establishing a standard fingerprint, establishing a fingerprint of a sample and comparing the standard fingerprint with the fingerprint of the sample. The standard fingerprint of the compound anti-inflammatory and cholagogic preparation shows 15 main chromatographic peaks in 225nm and confirms the chemical structures of 8 chromatographic peaks in the 15 main chromatographic peaks. The active ingredients with anti-inflammatory effect of three ingredients comprising andrographolide, rosemarinic acid and nigakinone in the 8 chemical structures are further confirmed. As the supplementation of the method, the three ingredients or the combination of the three ingredients can be indicative ingredients used for carrying content measurement. The method has high repeatability, good stability and simple and convenient operating method, is scientific with evidences and can effectively control the quality of the compound anti-inflammatory and cholagogic preparation.

The invention discloses an externally used Chinese medicinal herbal preparation for trauma infestation resistance, inflammation diminishing and pain reduction, and the process for preparation, wherein the preparation is made from the ethanol extract of goose grass, notoginseng and boneol, the proportioning ratio can be adjusted at will, while the preferable weight ratio is, goose grass : notoginseng : borneol = 100-5:1:1-4.

The invention relates to a preparation method of an ion induction patch. The method comprises the following steps of: blending and mixing organic high polymer fine powder with nanometer far infrared powder, pressing a film, drying and sizing to obtain a film; performing ion transformation deposition micro-treatment on the film to form an ion deposition layer; placing metal foils onto both sides of the ion deposition layer respectively to obtain a metal foil ion deposition layer; and sticking one side of the metal foil ion deposition layer to a sticking base layer and covering a surface gloss paper support layer on the other side of the metal foil ion deposition layer to obtain an ion induction patch. According to a prepared product, the principle of the biological stimulation effects of a high-voltage electrostatic field, far infrared rays and microcurrent on human bodies is utilized comprehensively, and electrostatic ion induction directly acts on afflicted parts, so that the proliferation of abnormal cells is suppressed effectively, normal growth of benign cells is activated, local blood circulation is facilitated in combination with far infrared rays, blood acidity is lowered, metabolism is facilitated, and the immunity is enhanced; and the product has the effects of rapidly relieving pain, diminishing inflammation and subsiding swelling.

The invention relates to a defervescence anti-inflammatory and anti-infection medicine with immunization function, a preparation and an application thereof. Andrographolidume derivant is andrographolidume sodium bisulfite hydrate, and the molecular formula of the andrographolidume sodium bisulfite hydrate is C20H29O7SNa.nH2O, wherein n is equal to a number between 0.88 and 3.5. The derivant has better water solubility and better storage stability, and is suitable to prepare treatment or prevention medicines for reducing fever and relieving internal heat of fever, resisting bacteria and diminishing inflammation, resisting virus and allaying fever, and adjusting immunologic function.