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A rapid film-forming liquid band-aid containing the extract of oriental cypress leaves

A technology of oriental orientalis leaf and extract, applied in the field of medical supplies, can solve the problems of complex preparation process of liquid band-aids, poor film-forming properties of film-forming materials, and unfavorable rapid closure of wounds, etc. The effect of shortening the calcium time and shortening the film-forming time

Active Publication Date: 2021-09-21
中山大学新华学院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The main problems in the current research on liquid band-aids are that the preparation process of liquid band-aids is complicated, there are few types of film-forming materials, and the film-forming properties of film-forming materials are not good [Liu Haixia, Zhang Aijun, Zhang Lin. Research progress on liquid band-aids[J] .Chinese Medical Science, 2016,6(4):28-31]
Patent CN108992704A discloses a liquid band-aid made of ethanol, camphor, benzyl alcohol, Panax notoginseng extract, witch hazel extract, and polyurethane-35. The band-aid has good air permeability and anti-inflammatory and analgesic effects, but its composition The longer film time is 85-127s, which is not conducive to the rapid closure of the wound

Method used

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  • A rapid film-forming liquid band-aid containing the extract of oriental cypress leaves
  • A rapid film-forming liquid band-aid containing the extract of oriental cypress leaves
  • A rapid film-forming liquid band-aid containing the extract of oriental cypress leaves

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Example 1 Preparation and Performance Evaluation of Rapid Mosaic Liquid Substance

[0040] 1. Preparation of liquid creation

[0041] (1) Preparation of the lateral leaf extract

[0042] It is weighted 30g of veletine, placed in a conical bottle, adding 60% ethanol solution 500 mL for 3 hours, and extracts 20 min (ultrasonic frequency 40 kHz) at 60 ° C. 3500R · min after cooling to room temperature -1 15 min centrifuged, the filter residue was subjected to ultrasound extraction, centrifugation, combined filtrate, and sideway extract.

[0043] (2) Adding the preparation of liquid creation of the side cypress extract

[0044] The ethanol 25g, butyl acetate 23g and ethyl acetate 26g are mixed, and the mixture is added to the mixture while stirring the PVA 8g, and the mixture is closed (prevent volatilization) until dissolution;

[0045] S2. Add PVPK90 1.0G to continue to dissolve complete, add sorbitol 1.0g to mix;

[0046] S3. Add 1 to cycle extract to the above-mentioned pre...

Embodiment 2

[0065] Example 2 Preparation of liquid creation and performance evaluation

[0066] 1. Preparation of liquid creation

[0067] (1) Preparation of the lateral leaf extract

[0068] It is weighted 30g of veletine, placed in a conical bottle, adding 60% ethanol solution 500 mL for 3 hours, and extracts 20 min (ultrasonic frequency 40 kHz) at 60 ° C. After cooling to room temperature, 3500r · min-1 centrifuge for 15 min, and the filter residue was subjected to ultrasound extraction, centrifugal separation, combined filtrate, and obtained a side cypress extract.

[0069] (2) Adding a latex extract liquid creation

[0070] S1. Take ethanol 23 g, butyl acetate 25g and ethyl acetate 28 g, and the mixed liquid is added to the stirring edge of PVA 9g, and the mixture is closed (prevent volatilize) until dissolved;

[0071] S2. Add PVPK90 1.5G to continue to dissolve completely, add sorbitol 1.5G mixing;

[0072] S3. The 2G velicular leaf extract was added to the above-mentioned preparation ...

Embodiment 3

[0085] Example 3 Preparation and Performance Evaluation of Liquid Instruments

[0086] 1. Preparation of liquid creation

[0087] (1) Preparation of the lateral leaf extract

[0088] It is weighted 30g of veletine, placed in a conical bottle, adding 60% ethanol solution 500 mL for 3 hours, and extracts 20 min (ultrasonic frequency 40 kHz) at 60 ° C. After cooling to room temperature, 3500r · min-1 centrifuge for 15 min, and the filter residue was subjected to ultrasound extraction, centrifugal separation, combined filtrate, and obtained a side cypress extract.

[0089] (2) Adding a latex extract liquid creation

[0090] S1. Take ethanol 23 g, butyl acetate 23g and ethyl acetate 21 g, and the mixture is added to the mixed liquid while stirring at PVA 6g, and the mixture is closed (prevent volatilization) until dissolved;

[0091] S2. Add PVPK90 0.5G to continue to dissolve complete, add sorbitan 0.5g to mix;

[0092] S3. Add 1 to cycle extract to the above-mentioned preparation mix...

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Abstract

The invention discloses a fast film-forming liquid band-aid containing the extract of oriental cypress leaves. The experiment of the present invention finds that the addition of the orientalis leaf extract to the liquid band-aid formula can significantly improve the film-forming property, greatly shorten the film-forming time, and at the same time greatly shorten the plasma recalcification time. And developed a kind of liquid band-aid, this liquid band-aid is prepared by ethyl acetate, butyl acetate, ethanol, PVA, PVPk90, sorbitol, peppermint oil, orientalis leaf extract, and the obtained containing orientalis leaf extract The liquid band-aid can effectively shorten the plasma recalcification time, promote wound hemostasis, and the film-forming time is short, it can quickly dry and form a breathable and waterproof elastic protective film, which can instantly seal the wound surface, prevent wound infection and bacterial invasion, and promote wound healing heal.

Description

Technical field [0001] The present invention relates to the field of medical supplies, and in particular, to a rapid film formation liquid creation of a side cypress extract. Background technique [0002] Traditional record can oppress hemostasis, protect wounds, prevent infection, promote healing, and has the advantages of simple use, easy to carry. However, the adulse is inferior, and water vapor and sweat which are normal secreted by the body cannot penetrate this layer of tape, so that the skin produces soaked to make the skin wrinkles. [0003] Liquid Bandage is dissolved in a solvent by a film forming material, and is adhered to the skin wound portion by applying or spraying, forming a translucent protective film, has a split, ventilated, waterproof, convenient, easy to observe wound conditions. And promote wound recovery, etc., due to its excellent performance, it is gradually applied in the pharmaceutical industry. Liquid creation can include two categories, one type is s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L26/00
CPCA61L26/0014A61L26/0057A61L26/0061A61L26/0066A61L2300/30A61L2300/412A61L2400/04C08L29/04C08L39/06
Inventor 徐娟娟成燕琴曹颖男郑晖晖何杺虞
Owner 中山大学新华学院
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