High-adhesion-property Lactobacillus helveticus strain with immunity enhancement function and application thereof

A technology that enhances immunity and high adhesion, applied in the field of microorganisms, can solve the problems of undiscovered lactic acid bacteria, and achieve good acid and bile salt resistance, excellent adhesion characteristics, and high safety effects

Active Publication Date: 2020-06-09
HANGZHOU WAHAHA TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the efficacy of probiotics is strain-specific, and there are still man

Method used

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  • High-adhesion-property Lactobacillus helveticus strain with immunity enhancement function and application thereof
  • High-adhesion-property Lactobacillus helveticus strain with immunity enhancement function and application thereof
  • High-adhesion-property Lactobacillus helveticus strain with immunity enhancement function and application thereof

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Experimental program
Comparison scheme
Effect test

Embodiment

[0042] 1. Isolation and cultivation of strains

[0043] A strain of Lactobacillus helveticus with the function of enhancing immunity was screened by the inventor from the yogurt collected from Hongshangou in Nalati, Xinjiang in the previous work. It was identified as Lactobacillus helveticus, named WHH2580, and was deposited in the General Microorganism Culture Collection Center of China Microbiology Culture Collection Management Committee on October 23, 2019, and its microorganism preservation number is: CGMCC No.18730. The biological properties of the strain are as follows:

[0044] Morphological characteristics: The growth state in MRS agar medium is: the growth form in MRS agar medium is light milky white colony, translucent, round, rough surface, irregular edges, and flattened. Gram staining was typically positive. Under the microscope, the cells were long rod-shaped, without flagella, spore-forming, and motionless.

[0045] Culture characteristics: The optimum growth tem...

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Abstract

The invention belongs to the technical field of microorganisms, and discloses a high-adhesion-property Lactobacillus helveticus strain with an immunity enhancement function. The Lactobacillus helveticus strain is named WHH2580, and is preserved in the China General Microbiological Culture Collection Center since October 23, 2019 under the preservation number of CGMCC No. 18730. The Lactobacillus helveticus strain has a classification name of Lactobacillus helveticus. The invention further discloses application of the Lactobacillus helveticus strain. The Lactobacillus helveticus strain disclosed by the invention has excellent adhesion property in both active form and inactivated form, and is capable of enhancing body immunity by improving and regulating organ index of the body as well as nonspecific immune response and specific immune response. Moreover, the Lactobacillus helveticus strain disclosed by the invention has immunity regulation effects such that corresponding compositions can be ingested so as to improve decreased immune functions by activating the immune functions.

Description

technical field [0001] The invention relates to the technical field of microbes, in particular to a high-adhesive Lactobacillus helveticus strain capable of enhancing immunity and its application. Background technique [0002] Probiotics are beneficial microorganisms that can exert physiological functions in the human intestinal tract and contribute to health. After being ingested by the host, they adhere to the intestinal mucosal epithelial cells and colonize to form a stable flora. A large number of studies have proved that some lactic acid bacteria species can have beneficial effects on the host, not only helping to maintain the balance of intestinal microecology and absorption of nutrients, but also regulating the immune function of the host, promoting the improvement of intestinal mucosal barrier function and enhancing the immune system. ability to infect. [0003] Adhesion is not only the prerequisite for the colonization of probiotics in the intestinal tract, but als...

Claims

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Application Information

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IPC IPC(8): C12N1/20A61K35/747A61P37/04A23C9/123A23C19/06A23C19/032A23C9/16A23L19/00A23L33/135C12R1/225
CPCA61K35/747A61P37/04A23C9/1234A23C19/061A23C19/032A23C9/16A23L19/00A23L33/135A23V2002/00C12R2001/225C12N1/205A23V2400/147A23V2200/324
Inventor 陈丽娥陈苏孙盛俞赟霞陈彩玲李言郡任学良翁璐溦郑志瑶朱珺李理
Owner HANGZHOU WAHAHA TECH
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