Antigen harvesting device for infectious bronchitis

A bronchitis and harvesting device technology, applied in the direction of biochemical instruments, specific-purpose bioreactors/fermenters, biochemical equipment and methods, etc., can solve the problem that the yolk is easy to be punctured and absorbed, the effective yield is not high, and the cultivation time Short and other problems, to achieve the effect of thorough absorption, cost reduction, and improvement of harvest quality

Pending Publication Date: 2020-10-13
兆丰华生物科技(南京)有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, in the production process of chicken infectious bronchitis antigen, the incubation time of infectious bronchitis virus is relatively short, and the egg yolk shrinkage takes a long time, so that the egg yolk is easily punctured, sucked and mixed into the harvested allantoic fluid during the harvesting process. In this way, the antigen is turbid, the titer is not high and unstable, and the effective yield is not high, and the yolk harvest rate is as high as 98%.

Method used

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  • Antigen harvesting device for infectious bronchitis
  • Antigen harvesting device for infectious bronchitis
  • Antigen harvesting device for infectious bronchitis

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Embodiment Construction

[0019] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0020] see figure 1 and image 3 , the present invention provides a technical solution:

[0021] A chicken infectious bronchitis antigen harvesting device, comprising a harvesting head, the harvesting head includes a suction rod 7 and a jacket, and the jacket is connected by a suction rod insertion head 3 arranged sequentially from top to bottom and a suction rod jacket 6 Formed, the lower end of the liquid suction rod coat 6 is a beveled sharp head 1, and ...

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Abstract

The invention relates to the technical field of antigen harvesting, and especially relates to an antigen harvesting device for infectious bronchitis. The harvesting device includes a harvesting head;the harvesting head includes a liquid suction rod (7) and a coat; the coat is formed by a liquid suction rod inserting head (3) and a liquid suction rod coat (6) in successive arrangement from top tobottom through connection; the lower end of the liquid suction rod coat (6) is a beveled sharp head (1), and the included angle between the inclined plane of the beveled sharp head (1) and a horizontal plane is 30-45 degrees; and the sidewall, on the same side with the tip of the beveled sharp head (1), of the liquid suction rod coat (6) is provided with multiple liquid suction holes (2). The beveled sharp head of the device is only in contact with the eggshell edge of chicken embryo during harvesting, and the incline plane can effectively avoid the yolk when going down; and the harvesting head has more liquid suction holes at the top part and less liquid suction holes at the bottom part, so that liquid suction rod can be further shortened, therefore, blocking can be effectively avoided, allantoic fluid can be quickly sucked, and thorough suction can be achieved.

Description

technical field [0001] The invention relates to the technical field of antigen harvesting, and the specific field is an antigen harvesting device. Background technique [0002] The chicken embryo culture method is a commonly used method for culturing viruses. The chicken embryo culture method is easy to operate and is suitable for the cultivation of influenza virus, encephalitis virus, and Newcastle disease virus. There are many inoculation methods for chicken embryo culture, the most commonly used are: chorioallantoic membrane inoculation, amniotic cavity inoculation, allantoic cavity inoculation and yolk sac inoculation. According to the characteristics of the virus, the appropriate inoculation route can be selected. [0003] At present, in the production process of chicken infectious bronchitis antigen, the incubation time of infectious bronchitis virus is relatively short, and the egg yolk shrinkage takes a long time, so that the egg yolk is easily punctured, sucked and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/32C12M3/10
CPCC12M21/10C12M33/04
Inventor 顾玉美蔡勇飞黄永伟郭振鑫
Owner 兆丰华生物科技(南京)有限公司
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