Anti-coronavirus traditional Chinese medicine composition as well as preparation method and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition, treatment of coronavirus disease, novel coronavirus pneumonia, preparation of said traditional Chinese medicine composition, can solve problems such as unsatisfactory

Active Publication Date: 2020-10-20
SHANDONG BUCHANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Therefore, there is an unmet need for traditional Chinese medicine composition

Method used

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  • Anti-coronavirus traditional Chinese medicine composition as well as preparation method and application thereof
  • Anti-coronavirus traditional Chinese medicine composition as well as preparation method and application thereof
  • Anti-coronavirus traditional Chinese medicine composition as well as preparation method and application thereof

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preparation example Construction

[0079] In the preparation process of the Chinese medicine active extract of the present invention, the obtained extract is preferably filtered, for example, through a 100-300 mesh sieve, and centrifuged using methods and equipment commonly used in the art.

[0080] Those skilled in the art know that in any embodiment of this aspect, the amount of water added, the extraction time and the number of extractions are not absolute, that is, the corresponding parameter values ​​outside the range and close to the end value of the range are used It is also possible to achieve the object of the present invention. All obvious variations of the above-described embodiments are therefore intended to be within the scope of the invention.

[0081] According to the Chinese medicine composition of the present invention, except comprising the Chinese medicine active extract of the present invention involved in any form of the above-mentioned aspects, it can also include pharmaceutically acceptab...

Embodiment 1

[0116] The preparation of Chinese medicine composition (granule) of the present invention

[0117] Recipe composition:

[0118] Ephedra 150g, Bitter Almond 375g, Gypsum 750g, Coix Seed 750g, Atractylodes 250g, Patchouli 375g, Verbena 750g, Polygonum cuspidatum 500g, Reed Root 750g, Tinglizi 375g, Huajuhong 375 grams, Artemisia annua 300 grams and licorice 250 grams.

[0119] Preparation of active extract of traditional Chinese medicine:

[0120] The above thirteen flavors are decocted with licorice alone, and the rest of the medicinal flavors are first extracted with gypsum in ten times the amount of water or alcohol solution for 30 minutes. Filter the filtrate, add Artemisia annua and Huoxiang to the dregs, then add six times the amount of water to extract for 30 minutes, combine the extracts, and concentrate below 60°C; add 10 times the amount of water to extract licorice twice, each time for one hour, and concentrate the filtrate to an appropriate amount ; The relative d...

Embodiment 2

[0124] The preparation of Chinese medicine composition (granule) of the present invention

[0125] Recipe composition:

[0126] 240 grams of ephedra, 600 grams of bitter almonds, 1200 grams of raw gypsum, 1200 grams of coix seed, 400 grams of herb, 600 grams of patchouli, 1200 grams of verbena, 800 grams of knotweed, 1200 grams of reed root, 600 grams of Tinglizi, and red orange 600 grams, 480 grams of Artemisia annua and 400 grams of licorice.

[0127] Preparation of active extract of traditional Chinese medicine:

[0128] Take the indicated amount of decoction pieces (except licorice) for each batch, decoct twice, add 10 times the water once decocting, first decoct raw gypsum for 30 minutes, then decoct other herbs (except artemisia annua and patchouli) for 60 minutes, filter To obtain the first decoction extract, add Artemisia annua and Patchouli, add 6 times the water along with the first decoction residue, decoct the second decoction for 30 minutes, filter the extract t...

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Abstract

The invention relates to an anti-coronavirus traditional Chinese medicine composition as well as a preparation method and application thereof. The traditional Chinese medicine composition comprises traditional Chinese medicine active extract, and the active extract consists of first extract and second extract. The first extract is an aqueous extract or an alcohol-water extract of ephedra, semen armeniacae amarae, gypsum, semen coicis, rhizoma atractylodis, pogostemon cablin, polygonum cuspidatum, verbena, rhizoma phragmitis, semen lepidii, exocarpium citri grandis and artemisia apiacea, and the second extract is an aqueous extract or an alcohol-water extract of liquorice. The first extract and the second extract are independently extracted. The traditional Chinese medicine composition canbe used for treating coronavirus diseases such as novel coronavirus pneumonia.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition, which can be used to treat coronavirus diseases, such as novel coronavirus pneumonia (COVID-19). The present invention also relates to a method for preparing the Chinese medicine composition, and the use of the Chinese medicine composition for treating coronavirus diseases. Background technique [0002] Coronaviridae viruses are a large group of viruses that widely exist in nature and infect vertebrates, such as humans, mice, pigs, cats, dogs, wolves, chickens, cattle, and birds. The new coronavirus (SARS-CoV-2) belongs to the β-coronavirus in the Coronaviridae family, and its genetic characteristics are significantly different from those of SARSr-CoV and MERSr-CoV. The new coronavirus is sensitive to ultraviolet light and heat. Lipid solvents such as ether, 75% ethanol, chlorine-containing disinfectant, peracetic acid, and ...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61P31/14A61P11/00A61K33/06
CPCA61K36/17A61K36/736A61K33/06A61K36/8994A61K36/284A61K36/532A61K36/704A61K36/85A61K36/899A61K36/31A61K36/752A61K36/282A61K36/484A61P31/14A61P11/00A61K2300/00Y02A50/30
Inventor 张伯礼刘清泉高秀梅张俊华宋新波张磊王毅杨丰文郑文科王涛王跃飞张晗黄宇虹王苹刘二伟刘岱琳张静泽黄明
Owner SHANDONG BUCHANG PHARMA
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