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Radix bupleuri detoxification pharmaceutical composition as well as preparation method and application thereof

A technology of composition and medicine, which is applied in the field of Bupleurum detoxification medicine composition and its preparation, can solve the problems that the treatment effect of severe patients with new coronary pneumonia needs to be studied, and achieve the effect of improving fever, flushing and chest tightness

Inactive Publication Date: 2020-11-13
GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The pathogenesis of the cold-damp stagnant lung syndrome in the early stage of new coronary pneumonia is different from that of the severe disease-toxin closed-lung syndrome of new coronary pneumonia, so the treatment effect of this prescription on patients with severe new coronary pneumonia of the disease-toxin closed-lung type remains to be studied

Method used

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  • Radix bupleuri detoxification pharmaceutical composition as well as preparation method and application thereof
  • Radix bupleuri detoxification pharmaceutical composition as well as preparation method and application thereof
  • Radix bupleuri detoxification pharmaceutical composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Bupleurum Jiedu Decoction is prepared from the following components: 30g Bupleurum, 15g Scutellaria, 15g Pinellia, 15g Ginger, 5g Jujube, 20g Citrus aurantium, 10g Rhubarb, 10g peach kernel, and 15g Radix Paeoniae Alba.

[0043] The above components are taken, and Bupleurum Jiedu Decoction is prepared according to the existing preparation method of traditional Chinese medicine decoction. The proportion is one dose, and one dose is about 200ml.

[0044] Exemplarily, Bupleurum Jiedu Decoction can be prepared by the following existing methods:

[0045] Add water equivalent to 10 times the total mass of the crude drug, heat to boil, and keep boiling slightly for 2 hours to obtain the first decoction and medicinal residues after separation; for the second time, take the medicinal residues obtained after the first decoction, add Water equivalent to 8 times the total mass of the raw material medicine, heated to boiling, and kept at a slight boil for 1.5 hours, separated to obt...

Embodiment 2

[0048] Bupleurum Jiedu Granules are prepared from the following components: 30g Bupleurum, 15g Scutellaria, 15g Pinellia, 15g Ginger, 5g Jujube, 20g Citrus aurantium, 10g Rhubarb, 10g peach kernel, and 15g Radix Paeoniae Alba.

[0049] Take the above components, add carriers or / excipients, and prepare 1000 g of Bupleurum detoxification granules according to the existing preparation method of traditional Chinese medicine granules.

[0050] Exemplarily, Bupleurum detoxification granules can be prepared by the following existing methods:

[0051] (1) Take bupleurum and ginger and add 12 times of water to soak for 1 hour, distill for 8 hours, collect volatile oil, collect the distilled water and liquid in another device, add 10 times of water to decoct the distilled medicinal residues twice, 1.5 hours each time to obtain the decoction, and then combine the obtained decoction with the distilled water to obtain the water extract; the collected volatile oil is clathrated with β-cyclo...

Embodiment 3

[0057] Bupleurum Jiedu Tablets are prepared from the following components: Bupleurum 30g, Scutellaria baicalensis 15g, Pinellia fragrans 10g, Ginger 15g, Jujube 15g, Citrus aurantium 30g, Rhubarb 15g, Peach kernel 15g, Radix Paeoniae Alba 30g.

[0058] Take the above components, add carriers or / excipients, and prepare Bupleurum detoxification tablets according to the existing preparation method of traditional Chinese medicine tablets.

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Abstract

The invention belongs to the field of traditional Chinese medicines, in particular to a radix bupleuri detoxification pharmaceutical composition and a preparation method and an application thereof. The radix bupleuri detoxification pharmaceutical composition is prepared from the following raw material components in parts by mass: 30-60 parts of radix bupleuri, 15-30 parts of radix scutellariae, 15-30 parts of rhizoma pinellinae praeparata, 15-30 parts of fresh ginger, 5-10 parts of Chinese dates, 20-40 parts of fructus aurantii immaturus, 10-20 parts of radix et rhizoma rhei, 10-20 parts of peach kernels and 15-30 parts of radix paeoniae alba. The radix bupleuri detoxification pharmaceutical composition disclosed by the invention has the advantages that the cough caused by common COVID-19can be obviously improved; the traditional Chinese medicine composition can improve cough caused by the epidemic toxin lung-closed type severe COVID-19, and remarkably improve main symptoms such as chest distress, shortness of breath and weakness caused by the epidemic toxin lung-closed type severe COVID-19. In addition, through a large number of clinical observations, the radix bupleuri detoxification pharmaceutical composition disclosed by the invention can significantly improve symptoms such as fever with redness, cough, yellow and sticky phlegm, or blood-carrying phlegm, asthma and suffocation, fatigue, dry and bitter mouth, unsmooth defecation, short and red urine and the like caused by the epidemic toxin lung-closing type heavy COVID-19.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a medicinal composition of Bupleurum bupleuri and its preparation method and application. Background technique [0002] Coronavirus disease( Corona Virus Disease 2019, COVID-19 ), referred to as "New Coronary Pneumonia", is the pneumonia caused by the 2019 novel coronavirus infection. The sixth edition of the "Diagnosis and Treatment Plan for Novel Coronavirus Pneumonia" divides COVID-19 into a medical observation period and a clinical treatment period (confirmed cases) in the diagnosis and treatment part of traditional Chinese medicine. The clinical treatment period (confirmed cases) is divided into mild, common, severe, Critical type and convalescent stage, severe type can be divided into epidemic poison closed lung syndrome and qi camp two burnt syndrome. Due to severe hypoxia, respiratory failure, multiple organ failure, etc., severe and critical dis...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P31/14
CPCA61K36/233A61K36/539A61K36/65A61K36/708A61K36/71A61K36/725A61K36/736A61K36/752A61K36/8888A61K36/9068A61P31/14A61K2300/00
Inventor 张忠德邹旭颜芳刘云涛丁邦晗金连顺唐丽娟
Owner GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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