medical composition, traditional Chinese medicine composition, traditional Chinese medicine extract, preparation of traditional Chinese medicine extract, medicament and application of medical composition, traditional Chinese medicine composition and traditional Chinese medicine extract
A composition and drug technology, applied in the field of medicine, can solve problems such as side effects, drug resistance, and uncertain curative effect
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[0170] The preparation method of mangosteen fruit peel extract in technology one is as follows:
[0171] 2.5 kg of mangosteen pericarp was crushed and passed through a 10-mesh sieve, then 20 L of 75% (v / v) ethanol-water was added and heated under reflux to extract twice, each time for 2 hours. The extracts were combined, filtered with gauze, centrifuged at 1200 rpm for 10 minutes, the supernatant was concentrated, and freeze-dried to obtain a mangosteen pericarp extract (300 g). The above extract was dissolved in an appropriate amount of water, filtered, and the filtrate was subjected to open column chromatography on a macroporous resin HP-20, ethanol-water gradient elution. It was eluted successively with water, 30% (v / v) ethanol-water, and 90% (v / v) ethanol-water. Collect the eluted part of 90 (v / v) ethanol-water, concentrate under reduced pressure, control the temperature below 55°C, control the vacuum degree above 0.05MPa, and concentrate to about 25 degrees Celsius to ob...
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