Ceramide composition and preparation method thereof

Abstract

The invention aims to disclose a ceramide composition and a preparation method thereof. The ceramide composition is prepared from the following components in percentage by mass: 5%-95% of ceramide 3 and 5%-95% of ceramide 6 II. Compared with the prior art, the ceramide composition exogenously provides the ceramide so as to maintain the ceramide level of the skin, has a reasonable formula, relievessymptoms including itching, redness and swelling, cracking and the like caused by atopic dermatitis, has very high capacity of associating water molecules, and maintains the moisture of the skin by forming a net structure in the cuticle, so that the conductivity of the skin is improved; and the ceramide composition has powerful water locking capacity, increases the thickness of the cuticle, improves the water holding capacity of the skin, enhances the elasticity of the skin, can also properly reduce the inflammatory response, reconstructs the damaged skin barrier function, can be used for assisting the treatment of skin barrier dysfunction related diseases, and achieves the purpose of the invention.

Description

technical field [0001] The invention relates to a composition and a preparation method thereof, in particular to a ceramide composition used in moisturizing cream or shower gel for infants and young children and a preparation method thereof. Background technique [0002] The main component of the lipid structure of the stratum corneum of the skin is ceramides, which have the functions of locking water, inhibiting inflammation and promoting the repair of skin barrier function, and play a leading role in the regulation of skin barrier function. [0003] Studies have shown that in patients with atopic dermatitis, the proliferation ability of keratinocytes is reduced, the content of ceramide is significantly reduced, and the skin barrier function is weakened. Skin diseases related to genetics and environment such as atopic dermatitis are still difficult problems in clinical treatment, seriously affecting the quality of life of patients. [0004] Traditional treatment mainly use...

AI Technical Summary

Problems solved by technology

[0004] Traditional treatment mainly uses antihistamines and glucocorticoids, among which antihistamines can relieve skin lesions in the acute phase, but are not effective in repairing the skin barrier function in the remission phase, and cannot solve the problem of recurrence after drug withdrawal; Glucocorticoids can reduce local inflammation and relieve itching symptoms, but long-term use can cause skin atrophy, pigmentation, telangiectasia and other adverse reactions, and long-term use can cause treatment resistance and addiction, and it is easy to cause recurrence of skin lesions after drug withdrawal

[0005] Therefore, the current methods for the treatment of dermatological diseases related to skin barrier dysfunction are not ideal.