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Hardness-softening powder composition

A technology of composition and mixed powder, which is applied in the directions of drug combination, plant raw materials, plant/algae/fungus/moss components, etc., can solve the problems of reduced quality of life of patients, damage to liver function, poor prognosis, etc., to avoid intestinal Inactivation, prolonging release time, reducing adverse reactions and body burden

Pending Publication Date: 2021-04-20
THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] For the treatment of liver cirrhosis, although Western medicine has a certain effect, it has disadvantages such as large side effects, high recurrence rate, high cost, and reduced quality of life of patients.
Due to the poor liver function of patients with liver cirrhosis, there is a risk of further damage to liver function in daily oral medication; surgical treatment is often chosen in the middle and late stages of the disease, but the overall condition of the patient at this time may lead to a poor prognosis

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] As a kind of Ruanjian powder composition of the embodiment of the present invention, described Ruanjian powder composition comprises the following components by weight: 20.6 parts of cloves, 34.4 parts of Zanthoxylum bungeanum, 34.4 parts of Peony, 6.8 parts of Kansui, 34.4 parts Radix Paeoniae Rubra, 34.4 parts of Danshen and 34.4 parts of peach kernel.

Embodiment 2

[0036] As a kind of Ruanjian powder composition of the embodiment of the present invention, described Ruanjian powder composition comprises the following components by weight: 15 parts of cloves, 25 parts of Zanthoxylum bungeanum, 25 parts of Semen japonicus, 8 parts of Kansui, 40 parts 40 parts of red peony root, 40 parts of salvia miltiorrhiza and 40 parts of peach kernel.

Embodiment 3

[0038] As a kind of Ruanjian powder composition of the embodiment of the present invention, described Ruanjian powder composition comprises the following components by weight: 25 parts of cloves, 40 parts of Zanthoxylum bungeanum, 40 parts of Semen japonicus, 5 parts of Kansui, 25 parts of 25 parts of red peony root, 25 parts of salvia miltiorrhiza and 25 parts of peach kernel.

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PUM

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Abstract

The invention provides a hardness-softening powder composition, which comprises the following components in parts by weight: 10-30 parts of clove, 15-50 parts of Chinese prickly ash, 15-50 parts of semen pharbitidis, 3-10 parts of euphorbia kansui, 15-50 parts of radix paeoniae rubra, 15-50 parts of radix salviae miltiorrhizae and 15-50 parts of peach kernels. The hardness-softening powder composition disclosed by the invention can play a synergistic effect by being matched with clove, Chinese prickly ash, semen pharbitidis, euphorbia kansui, radix paeoniae rubra, radix salviae miltiorrhizae and peach kernels, has a certain curative effect on liver cirrhosis treatment, can prolong the drug release time at a constant drug delivery rate through meridian infection and transdermal action by utilizing a traditional Chinese medicine application therapy, avoid the liver first-pass effect and the intestinal tract inactivation effect at the same time, increase the drug utilization rate, reduce adverse reactions and body burdens of drugs, improve the application safety, and successfully treat liver cirrhosis.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a Ruanjian powder composition. Background technique [0002] Liver cirrhosis is a chronic, progressive, diffuse inflammatory and fibrotic liver disease caused by various reasons. Modern medicine believes that under the repeated or continuous action of pathogenic factors, liver cells show diffuse degeneration, necrosis, and apoptosis; residual liver cells regenerate and form regenerative nodules; connective tissue diffusely proliferates to form fibrous septa, and finally divides and destroys normal cells. Hepatic lobular structure, replaced by pathological changes characterized by sclerotic nodules or pseudolobules, clinical manifestations of liver dysfunction and portal hypertension. The average incidence of liver cirrhosis is 17.1 / 100,000, and the annual death toll is about 500,000. Modern medical treatment of cirrhosis is mainly based on etiological treatment and symptomatic tr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/758A61P1/16
Inventor 刘凤斌陈斌李培武杨云英庄昆海潘静琳钟卓泰何龙兰绍阳张铮铮赵利娜洪日侯秋科
Owner THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU UNIV OF CHINESE MEDICINE
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