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Traditional Chinese medicine composition for improving sleep and preparation method of preparation thereof

A technology for improving sleep and traditional Chinese medicine preparations, applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve problems such as psychomotor impairment, memory impairment, and easy jumping insomnia, and achieves mild preparation process conditions. The effect of improving sleep

Pending Publication Date: 2021-04-30
ZHONGJING WANXI PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Benzodiazepines can easily lead to adverse reactions such as psychomotor impairment, memory impairment, drug addiction, and jumping insomnia after drug withdrawal
Non-benzodiazepines have less side effects such as insomnia rebound, withdrawal syndrome, and memory impairment, but are prone to drug resistance, addiction, and dependence

Method used

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  • Traditional Chinese medicine composition for improving sleep and preparation method of preparation thereof
  • Traditional Chinese medicine composition for improving sleep and preparation method of preparation thereof
  • Traditional Chinese medicine composition for improving sleep and preparation method of preparation thereof

Examples

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Effect test

Embodiment 1

[0018] The present invention can be realized by the following methods in concrete implementation: the traditional Chinese medicine composition for improving sleep is made by the following raw materials by weight: 1 part of lily, 1 part of rehmannia glutinosa, 1 part of wheat, 2 parts of Chinese jujube, jujube seed 2 parts, 0.5 part of licorice, the preparation method of the preparation is as follows: take lily, rehmannia glutinosa, jujube, wheat, jujube seed, licorice, add water and reflux extraction twice, each time for 1.5h, each time adding water is lily, rehmannia glutinosa , jujube, wheat, wild jujube seed, 10 times the total weight of licorice, filter, combine two filtrates, concentrate under reduced pressure at 50°C to an extract with a specific gravity of 1.05 at 25°C, add ethanol to make the alcohol content reach a volume concentration of 15%, stand still for 8 hours, centrifuge at 5000r / min for 20min, take the supernatant and add ethanol until the alcohol content reac...

Embodiment 2

[0020] The present invention can be realized by the following methods in concrete implementation: the traditional Chinese medicine composition for improving sleep is made by following raw material medicine by weight: 3 parts of lily, 3 parts of rehmannia glutinosa, 3 parts of wheat, 4 parts of Chinese jujube, jujube seed 4 parts, 1.5 parts of licorice, the preparation method of the preparation is as follows: take lily, rehmannia glutinosa, jujube, wheat, jujube seed, licorice, add water and reflux for extraction twice, each time for 1.5h, each time adding water is lily, rehmannia glutinosa , jujube, wheat, wild jujube seed, 15 times the total weight of licorice, filter, combine two filtrates, concentrate under reduced pressure at 50°C to an extract with a specific gravity of 1.21 at 25°C, add ethanol to make the alcohol content reach a volume concentration of 15%, stand still for 8 hours, centrifuge at 5000r / min for 20min, take the supernatant and add ethanol until the alcohol ...

Embodiment 3

[0022] The present invention can be realized by the following methods in concrete implementation: the traditional Chinese medicine composition for improving sleep is made by the following raw materials by weight: 1.67 parts of lily, 1.67 parts of rehmannia glutinosa, 1.67 parts of wheat, 2.5 parts of Chinese jujube, Semen jujuba 2.5 parts, 1 part of licorice, the preparation method of the preparation is as follows: take lily, rehmannia glutinosa, jujube, wheat, jujube seed, licorice, add water and reflux for extraction twice, each time for 1.5h, each time adding water is lily, rehmannia glutinosa , jujube, wheat, wild jujube seed, 12 times the total weight of licorice, filter, combine two filtrates, concentrate under reduced pressure at 50°C to an extract with a specific gravity of 1.12 at 25°C, add ethanol to make the alcohol content reach a volume concentration of 15%, stand still for 8 hours, centrifuge at 5000r / min for 20min, take the supernatant and add ethanol until the a...

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Abstract

The invention relates to a traditional Chinese medicine composition for improving sleep and a preparation method of a preparation of the traditional Chinese medicine composition. The traditional Chinese medicine composition for improving sleep is prepared from the following components in parts by weight: 1-3 parts of lily, 1-3 parts of radix rehmanniae recen, 1-3 parts of wheat, 2-4 parts of Chinese dates, 2-4 parts of spina date seeds and 0.5-1.5 parts of liquorice. According to the preparation method of the traditional Chinese medicine composition preparation for improving sleep, a spiral-wound membrane filtration technology is introduced, the spinosin content in the prepared traditional Chinese medicine preparation for improving sleep is not lower than 0.1 mg / g, and the total content of jujuboside A and jujuboside B is not lower than 0.3 mg / g. Compared with a preparation prepared by a traditional process, the traditional Chinese medicine preparation for improving sleep prepared by the process has the effect of remarkably improving sleep.

Description

[0001] 1. Technical field [0002] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for improving sleep and a preparation method thereof. [0003] 2. Background technology [0004] One-third of life is spent in sleep, and the relationship between sleep and health has always been valued by people. The ancients had a saying that "I would rather eat without meat than sleep without sleep". Studies have shown that good sleep can eliminate fatigue, restore mental and physical strength, maintain a good awakening state, improve work and study efficiency, and prolong life. The main manifestations of insomnia are: difficulty in falling asleep, easy to wake up from light sleep, difficulty falling asleep after waking up, dreaminess, often accompanied by daytime malaise, weakness of limbs, unresponsiveness, low work efficiency, headache, memory loss and other symptoms. If you feel sleep deprivation f...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P25/20C08B37/00
CPCA61K36/484A61K36/725A61K36/804A61K36/8967A61K36/899A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61P25/20C08B37/0003A61K2300/00
Inventor 高松郭水柱张文峰
Owner ZHONGJING WANXI PHARMA CO LTD
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