Multi-mode mass spectrometry system and method

Abstract

The invention provides a multi-mode mass spectrometry system and method. The multi-mode mass spectrometry system comprises a first ion source, a second ion source and a multi-stage transmission rod, wherein the first ion source is an ion source under atmospheric pressure, a separation piece between a first vacuum chamber and a second vacuum chamber is provided with a first through hole suitable for ions to pass through, the interior of a container is separated into a first part and a second part by a first sliding piece, the first part is communicated with the second vacuum chamber, the second part is communicated with the first vacuum chamber, the first sliding piece sliding in the container is sealed with the inner wall of the container, one end of a connecting piece is connected with the first sliding piece, the other end of the connecting piece penetrates through the second part and is connected with a second sliding piece, the second sliding piece is provided with a second through hole, when the second sliding piece slides on the surface of the separation piece, the second sliding piece seals the first through hole, or the second through hole is communicated with the first through hole, and an elastic piece is connected with the second sliding piece and used for preventing the second sliding piece from moving towards the first part. The multi-mode mass spectrometry system has the advantages of low cost and the like.

Description

Technical field

[0001] The present invention relates to mass spectrometry, and more particularly to multi-mode mass spectrometry systems and methods.Background technique

[0002] GC-MS, LC-MS is two common mass spectrometry techniques, both of which are complementary, and the MS part is the same, so the GC-LC-MS-MS-MS-MS-formed GC-LC-MS-optimized applications and costs, there is very Large market advantage.

[0003] The vacuum requirements for the ion source of the two are different, GC (Ei / CI source) requires a vacuum degree above 1e-5 Torr, and it is necessary to directly block atmospheric pressure; LC (ESI / APCI source) works at the atmosphere, need The atmospheric pressure is transmitted by the transition of the multi-stage vacuum chamber.

[0004] For the same problem, Waters use the ion source to replace the problem, and need to be artificially disassembled, and the online switching of GC / LC two modes cannot be realized;

[0005] For vacuum partition problems, Hangzhou spent ICP-MS product...

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