A pharmaceutical composition containing tepagliflozin for treating diabetic cardiomyopathy

Abstract

The invention relates to the technical field of medicine, and specifically discloses a pharmaceutical composition containing tepagliflozin for treating diabetic cardiomyopathy. The pharmaceutical composition includes tepagliflozin and statin lipid-lowering drugs, and the statin lipid-lowering drugs include lovastatin, pravastatin, simvastatin, fluvastatin, atorvastatin, rosu One of Vastatin and Pitavastatin. Through the synergistic effect of tepagliflozin and statins, the blood sugar concentration of diabetic patients can be effectively controlled, and at the same time, it has a certain effect on the treatment of myocardial dysfunction caused by diabetes complications. safe and effective.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition containing tagagliflozin for treating diabetic cardiomyopathy. Background technique [0002] With the rapid development of social economy and the continuous improvement of people's living standards, the prevalence of diabetes among adults in my country has increased significantly, from 0.67% in 1980 to 10.4% in 2013. According to the 8th edition of the Global Diabetes Map released by the International Diabetes Federation (IDF) in 2017, the prevalence of diabetes in China was 10.9% in 2017, and the number of diabetic patients reached 114 million, accounting for 25% of the world's total adult diabetic patients. Above, ranking first in the world, this figure is still growing and is expected to increase to 120 million by 2045. Therefore, the prevention and treatment of diabetes is particularly important. At present, the treatment strategy o...

AI Technical Summary

Problems solved by technology

[0005] At present, most of the drugs for the treatment of diabetic cardiomyopathy are hypoglycemic drugs such as metformin, thiazolidinediones (insulin sensitizers), natural glucagon-like peptide-1, and dipeptidyl peptidase-4. There are certain toxic and side effects and use restrictions in the treatment of diabetic cardiomyopathy, so it is very urgent to continue research to find a drug that can effectively treat diabetic cardiomyopathy. For the treatment of diabetic cardiomyopathy

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