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A pharmaceutical composition containing tepagliflozin for treating diabetic cardiomyopathy

A technology of diabetic cardiomyopathy and composition, which is applied in the field of medicine, can solve the problems of undiscovered tepagliflozin, toxic and side effects, etc., achieve the effect of low drug toxic and side effects, reduce toxic and side effects, and enhance the therapeutic effect

Active Publication Date: 2022-05-06
GUANGZHOU LIXIN PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, most of the drugs for the treatment of diabetic cardiomyopathy are hypoglycemic drugs such as metformin, thiazolidinediones (insulin sensitizers), natural glucagon-like peptide-1, and dipeptidyl peptidase-4. There are certain toxic and side effects and use restrictions in the treatment of diabetic cardiomyopathy, so it is very urgent to continue research to find a drug that can effectively treat diabetic cardiomyopathy. For the treatment of diabetic cardiomyopathy

Method used

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  • A pharmaceutical composition containing tepagliflozin for treating diabetic cardiomyopathy
  • A pharmaceutical composition containing tepagliflozin for treating diabetic cardiomyopathy
  • A pharmaceutical composition containing tepagliflozin for treating diabetic cardiomyopathy

Examples

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Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1. The pharmaceutical composition of the present invention for the treatment of diabetic cardiomyopathy

[0023] It is made up of a mixture of Tagagliflozin 10g and Pravastatin 15g.

Embodiment 2

[0024] Embodiment 2. The pharmaceutical composition of the present invention for the treatment of diabetic cardiomyopathy

[0025] It is made up of a mixture of Tagagliflozin 5g and Pravastatin 20g.

Embodiment 3

[0026] Embodiment 3. The pharmaceutical composition of the present invention for the treatment of diabetic cardiomyopathy

[0027] It is made up of a mixture of Tagagliflozin 7g and Pravastatin 18g.

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PUM

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Abstract

The invention relates to the technical field of medicine, and specifically discloses a pharmaceutical composition containing tepagliflozin for treating diabetic cardiomyopathy. The pharmaceutical composition includes tepagliflozin and statin lipid-lowering drugs, and the statin lipid-lowering drugs include lovastatin, pravastatin, simvastatin, fluvastatin, atorvastatin, rosu One of Vastatin and Pitavastatin. Through the synergistic effect of tepagliflozin and statins, the blood sugar concentration of diabetic patients can be effectively controlled, and at the same time, it has a certain effect on the treatment of myocardial dysfunction caused by diabetes complications. safe and effective.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition containing tagagliflozin for treating diabetic cardiomyopathy. Background technique [0002] With the rapid development of social economy and the continuous improvement of people's living standards, the prevalence of diabetes among adults in my country has increased significantly, from 0.67% in 1980 to 10.4% in 2013. According to the 8th edition of the Global Diabetes Map released by the International Diabetes Federation (IDF) in 2017, the prevalence of diabetes in China was 10.9% in 2017, and the number of diabetic patients reached 114 million, accounting for 25% of the world's total adult diabetic patients. Above, ranking first in the world, this figure is still growing and is expected to increase to 120 million by 2045. Therefore, the prevention and treatment of diabetes is particularly important. At present, the treatment strategy o...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/351A61K45/06A61K31/366A61K31/22A61K31/405A61K31/40A61K31/505A61K31/47A61K31/4709A61P3/10A61P9/00
CPCA61K31/351A61K45/06A61K31/366A61K31/22A61K31/405A61K31/40A61K31/505A61K31/47A61K31/4709A61P3/10A61P9/00A61K2300/00
Inventor 高悦译刘恩桂张倩卢江
Owner GUANGZHOU LIXIN PHARM CO LTD