Application of Zixue prescription in preparation of consciousness promoted medicine for severe traumatic brain injury

A technology of brain injury and prescription, which is applied in the application field of Zixue prescription in the preparation of awakening drugs for severe brain injury, and can solve the problem of single awakening method

Pending Publication Date: 2021-09-07
TIANJIN HONGRENTANG PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The technical problem to be solved by the present invention is: the existing clinical wake-up promotion method only has multi-sensory wake-up promotion, and the wake-up promotion method is single.

Method used

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  • Application of Zixue prescription in preparation of consciousness promoted medicine for severe traumatic brain injury
  • Application of Zixue prescription in preparation of consciousness promoted medicine for severe traumatic brain injury
  • Application of Zixue prescription in preparation of consciousness promoted medicine for severe traumatic brain injury

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Experimental program
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experiment example

[0018] 1. Experimental materials

[0019] 1.1 Experimental animals

[0020] SPF grade male SD rats, weighing 200-220 g, were purchased from Beijing Weitong Lihua Experimental Animal Technology Co., Ltd., experimental animal production license number: SCXK (Beijing) 2016-0011. Breeding conditions: Raised in the SPF grade barrier room of Tianjin University of Traditional Chinese Medicine Animal Center, the temperature of the feeding room was (21±2)°C, the air pressure was constant, and day and night alternated for 12 hours.

[0021] 1.2 Drugs and reagents

[0022] Zixue powder (capsules, Tianjin Hongrentang Pharmaceutical Co., Ltd., batch number: 020236); chloral hydrate (Tianjin Damao Chemical Reagent Factory, batch number: 20200102); isoflurane (Shenzhen Ruiwode Life Technology Co., Ltd. , batch number: 20120701).

[0023] 1.3 Main instruments and equipment

[0024] Analytical balance (Shanghai Precision Scientific Instrument Co., Ltd. Balance Instrument Factory); surgical...

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Abstract

The invention relates to the technical field of traditional Chinese medicines, and discloses application of a Zixue prescription in preparation of a consciousness promoted medicine for severe traumatic brain injury. The severe traumatic brain injury refers to brain trauma caused by external force or brain trauma caused by cerebral hemorrhage. The consciousness promoted medicine can promote patients suffering from severe traumatic brain injury and coma to wake up in advance.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to the application of Zixue prescription in the preparation of awakening-promoting medicine for severe brain injury. Background technique [0002] Zixue powder is a classic resuscitating agent and one of the commonly used prescriptions of the cold opening method. It can treat coma and delirium caused by fever, and at the same time has the effect of "resuscitating and refreshing". [0003] Brain trauma (traumatic brain injury, TBI) has become the third largest disease in the world because of its high disability and high lethality, which seriously endangers human health. According to epidemiological studies, more than 50 million people suffer from severe traumatic brain injury (severe traumatic brain injury, sTBI) every year in the world, and as many as 10% to 15% of the survivors are in a persistent vegetative state or minimally conscious state for a long time d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/835A61P25/00A61P7/04A61K33/06A61K33/12A61K33/26A61K33/04A61K33/00A61K35/32A61K35/55A61K33/28A61K33/242
CPCA61K33/06A61K33/12A61K33/26A61K36/808A61K36/285A61K36/835A61K36/71A61K36/484A61K36/61A61K33/04A61K33/00A61K35/32A61K35/55A61K33/28A61K33/242A61P25/00A61P7/04A61K2300/00
Inventor 宋纹张慧叶学义彭晨苗
Owner TIANJIN HONGRENTANG PHARM CO LTD
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