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Medical antibacterial hemostatic gel dressing and preparation method thereof

A technology of hemostatic gel and raw materials, which is applied in the fields of medical formula, medical science, and resistance to media-borne diseases, etc., can solve the problem of unsatisfactory antibacterial and hemostatic performance, and achieve rapid hemostatic wound healing, no toxic side effects, and broad application prospects Effect

Active Publication Date: 2021-10-29
南通美泰医疗用品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the antibacterial and hemostatic properties of most gel dressings are not ideal at present. How to improve the antibacterial effect and hemostasis speed is still an important development direction of gel dressings.

Method used

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  • Medical antibacterial hemostatic gel dressing and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] A medical antibacterial hemostatic gel dressing, comprising the following raw material components in parts by weight: 5 parts of silk protein, 8 parts of calcium alginate, 1.4 parts of active silver ion, 8 parts of chitosan, 3 parts of dandelion extract, Prunella vulgaris 1.4 parts of extract, 0.8 parts of purple pearl grass extract, 1.5 parts of elm bark extract, 2.1 parts of wormwood extract, 0.2 parts of agave extract, 15 parts of metronidazole, 8 parts of hyaluronic acid, 10 parts of moisturizing agent parts, 35.6 parts of deionized water.

[0035] Among them, the purity of dandelion extract, Prunella vulgaris extract, Zizhucao extract, elm bark extract, wormwood extract and agave extract is not less than 85%. The humectant is one or more of glycerin, ethylene glycol, propylene glycol, butylene glycol, urea, sorbitol, and petrolatum. Chitosan is one or more of hydroxymethyl chitosan, hydroxyethyl chitosan, hydroxypropyl chitosan and quaternized chitosan. In this e...

Embodiment 2

[0050] A medical antibacterial hemostatic gel dressing, comprising the following raw material components in parts by weight: 10 parts of silk protein, 2 parts of calcium alginate, 2 parts of active silver ions, 12 parts of chitosan, 1.2 parts of dandelion extract, Prunella vulgaris 2 parts of extract, 1.2 parts of purple pearl grass extract, 0.5 parts of elm bark extract, 3 parts of wormwood extract, 0.9 parts of agave extract, 6 parts of metronidazole, 10 parts of hyaluronic acid, 12 parts of moisturizing agent parts, 37.2 parts of deionized water.

[0051] Among them, the purity of dandelion extract, Prunella vulgaris extract, Zizhucao extract, elm bark extract, wormwood extract and agave extract is not less than 85%. The humectant is one or more of glycerin, ethylene glycol, propylene glycol, butylene glycol, urea, sorbitol, and petrolatum. Chitosan is one or more of hydroxymethyl chitosan, hydroxyethyl chitosan, hydroxypropyl chitosan and quaternized chitosan. In this em...

Embodiment 3

[0066] A medical antibacterial hemostatic gel dressing, comprising the following raw material components in parts by weight: 15 parts of silk protein, 5 parts of calcium alginate, 0.8 parts of active silver ion, 16 parts of chitosan, 2.1 parts of dandelion extract, Prunella vulgaris 0.8 parts of extract, 1.5 parts of purple pearl grass extract, 1 part of elm bark extract, 1.2 parts of wormwood extract, 1.5 parts of agave extract, 10 parts of metronidazole, 5 parts of hyaluronic acid, 15 parts of moisturizing agent parts, 25.1 parts of deionized water.

[0067] Among them, the purity of dandelion extract, Prunella vulgaris extract, Zizhucao extract, elm bark extract, wormwood extract and agave extract is not less than 85%. The humectant is one or more of glycerin, ethylene glycol, propylene glycol, butylene glycol, urea, sorbitol, and petrolatum. Chitosan is one or more of hydroxymethyl chitosan, hydroxyethyl chitosan, hydroxypropyl chitosan and quaternized chitosan. In this ...

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Abstract

The invention provides a medical antibacterial hemostatic gel dressing and a preparation method thereof, and relates to the technical field of preparation technologies of medical gel dressings. The gel dressing comprises the following raw material components: fibroin, calcium alginate, active silver ions, chitosan, a dandelion extracting solution, a selfheal extracting solution, a callicarpa bodinieri extracting solution, an elm bark extracting solution, a wormwood extracting solution, a maguey extracting solution, metronidazole, hyaluronic acid, a humectant, deionized water and the like. The fibroin, the calcium alginate, the active silver ions, the chitosan, the metronidazole, the dandelion extracting solution, the prunella vulgaris extracting solution, the callicarpa bodinieri extracting solution, the elm bark extracting solution, the wormwood extracting solution, the agave extracting solution and other Chinese herbal medicine components are fused, all the raw material components have a synergistic effect, and the gel dressing has obvious enhancement of combined bacteriostasis, faster hemostasis, less irritation, no toxic and side effects, safe use, and good mechanical properties, and can avoid breakage during use.

Description

technical field [0001] The invention relates to the technical field of preparation of medical gel dressings, in particular to a medical antibacterial hemostatic gel dressing and a preparation method thereof. Background technique [0002] As the body's first biological defense barrier, the skin can prevent the invasion of bacteria and other microorganisms, and can also protect the body from physical and chemical factors in the external environment. Under the influence of acute trauma, burns and other factors, the skin's normal physiological functions and barrier functions It is destroyed, leading to the disturbance of water and electrolyte balance, the loss of nutrients or the occurrence of infection, etc., and even life-threatening. [0003] Gel dressing is a medical material that can temporarily protect wounds, prevent wound contamination, promote healing, and relieve pain. It is an important medical product that temporarily replaces damaged skin during the process of conti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/008A61L26/0066A61L26/0057A61L26/0023A61L26/0047A61L26/0004A61L26/0061A61L2300/404A61L2400/04A61L2300/412A61L2300/402A61L2300/30A61L2300/252A61L2300/232A61L2300/104A61L2300/236A61L2300/204C08L5/08C08L89/00C08L5/04Y02A50/30
Inventor 宋发开秦春梅李晓俊
Owner 南通美泰医疗用品有限公司
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