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Decision algorithm for treatment scheme of middle and advanced colorectal cancer

A colorectal cancer, treatment plan technology, applied in the direction of drugs or prescriptions, health index calculation, medical automatic diagnosis, etc. Effect

Pending Publication Date: 2022-04-08
HARBIN MEDICAL UNIVERSITY
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In the high-throughput detection of micro-sample, such as biopsy samples, CTC, and single-cell samples, it is necessary to amplify the RNA in the sample to a sufficient amount, and the overall amplification of nucleic acid substances is prone to bias, resulting in unreliable accurate detection values

Method used

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  • Decision algorithm for treatment scheme of middle and advanced colorectal cancer
  • Decision algorithm for treatment scheme of middle and advanced colorectal cancer
  • Decision algorithm for treatment scheme of middle and advanced colorectal cancer

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Embodiment Construction

[0032] In order to make the objects and advantages of the present invention clearer, the present invention will be further described below in conjunction with the examples; it should be understood that the specific examples described here are only for explaining the present invention, and are not intended to limit the present invention.

[0033] Preferred embodiments of the present invention are described below with reference to the accompanying drawings. Those skilled in the art should understand that these embodiments are only used to explain the technical principle of the present invention, and are not intended to limit the protection scope of the present invention.

[0034] In the description of this application, it should be noted that the combination of REO logos is a single-purpose logo, and the set of REO logos is the whole of REO logos for treatment decision-making in the middle and late stages of colorectal cancer in this patent.

[0035] The present invention adopts...

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Abstract

The invention discloses a middle and advanced colorectal cancer treatment scheme decision-making algorithm, which is used for carrying out individualized treatment prediction on a colorectal cancer patient and comprises the following steps: sequentially carrying out step-by-step REO marker evaluation on the colorectal cancer condition based on a gene expression profile of the patient in combination with clinical pathological staging and other biological characteristics of the colorectal cancer; a middle and advanced colorectal cancer treatment scheme decision algorithm model is constructed by using an REO mark set and is used for predicting the recurrence / metastasis risk of middle and advanced patients, the adjuvant chemotherapy benefit condition (middle-stage patients) and the drug resistance of immunotherapy and targeted therapy (advanced patients), and an optimal individualized treatment suggestion is given. The method provides more accurate and effective individualized treatment guidance for intestinal cancer patients, and has good application prospects and practical significance.

Description

technical field [0001] The invention relates to the field of cancer treatment, in particular to a decision-making algorithm for a treatment plan for middle and advanced colorectal cancer. Background technique [0002] According to the latest data on the global cancer burden in 2020 released by the WHO International Agency for Research on Cancer, there will be more than 1.93 million new cases of CRC (colorectal cancer) in the world in 2020, accounting for 9.7% of newly diagnosed cancers. In the same year, about 550,000 people in China were newly diagnosed with colorectal cancer, accounting for 12.2% of the number of newly diagnosed cancers in the world. Among them, the number of deaths from colorectal cancer in women is second only to lung cancer, and it has become the second leading cause of cancer death in women in China . In the past 30 years, the dietary structure and living habits of Chinese residents have changed, the incidence of colorectal cancer has continued to ris...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H20/10G16H50/30G16H50/20
Inventor 赵文媛李可如王永通常志强顾云燕戚丽霜刘志新
Owner HARBIN MEDICAL UNIVERSITY
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