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Chinese medicine soft capsule Naodesheng and its preparing method

A soft capsule, raw soft technology, applied in the directions of capsule delivery, pharmaceutical formulation, and drug combination, can solve the problems of slow disintegration and difficult absorption, and achieve the effects of inhibiting thrombus, improving bioavailability, and rational formulating

Inactive Publication Date: 2006-11-01
ANHUI AN TECH MEDICAL & BIOLOGICAL TECH
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Problems solved by technology

[0006] Naodesheng Tablet is a commonly used drug for treating cardiovascular and cerebrovascular diseases. Its original dosage form and preparation process have the following disadvantages: ①The original dosage form is a tablet, which disintegrates slowly and is not easy to absorb

Method used

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  • Chinese medicine soft capsule Naodesheng and its preparing method

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Embodiment Construction

[0034] Optimal choice of the formulation:

[0035] (1) "Naodesheng Tablets" is a variety included in the first edition of the 2000 edition of the "People's Republic of China" It is composed of five herbs of Panax Notoginseng, Chuanxiong, Safflower, Pueraria lobata and Hawthorn. It has the effects of promoting blood circulation, removing blood stasis, dredging the meridians, and rejuvenating the brain. It is used for cerebral arteriosclerosis, ischemic stroke and sequelae of cerebral hemorrhage. The original dosage form is a tablet, which disintegrates slowly and is not easy to absorb. The original dosage form uses Panax notoginseng and Pueraria lobata powder. Therefore, in order to make this formula more effective, we have carried out secondary development of this variety, and selected the dosage form as a soft product with the advantages of high bioavailability, good sealing, accurate content, rapid disintegration, beautiful appearance, and easy to take. capsule.

[0036] (2) Sel...

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Abstract

The invention discloses a new dosage form of the traditional Chinese medicine Naodesheng soft capsule for treating apoplexy and a preparation method thereof. The soft capsule preparation with the advantages of high bioavailability, good sealing, accurate content, rapid disintegration, and beautiful appearance was selected; the crude drug powder and water extraction process of the original production method were no longer used, and all medicinal materials were extracted with alcohol The full extraction method improves the extraction rate of active ingredients of each medicinal material, optimizes the content of active ingredients in the prescription, saves the amount of medicinal materials used and reduces the amount of crude drugs taken by patients. It is an invention project with higher technical content and technical added value. .

Description

Technical field [0001] The invention belongs to a kind of Chinese medicine, in particular, it is a preparation method and dosage form improvement of a Chinese patent medicine for the treatment of cerebral arteriosclerosis, ischemic stroke and sequelae of cerebral hemorrhage. Background technique [0002] With the development of society, cardiovascular and cerebrovascular diseases have become frequently-occurring and common diseases that endanger human health. At the end of 1998, among the causes of death of Chinese residents, the death rates of cerebrovascular and heart diseases among urban residents ranked second and third, while among rural residents, they ranked second and fourth. Experts predict that the incidence of cardiovascular and cerebrovascular diseases in the whole society is between 5% and 8%. The results of recent epidemiological surveys in 19 provinces and cities in my country with a population of 180,000 show that the current incidence of stroke is 600 / 100,000, of...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/734A61K36/48A61K36/286A61K36/258A61K36/236A61K9/48A61P9/10
Inventor 余世春
Owner ANHUI AN TECH MEDICAL & BIOLOGICAL TECH
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