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Chinese thorowax root screening and processing method

A processing method and technology of Bupleurum, applied in pharmaceutical formulas, plant raw materials, digestive systems, etc., can solve the problems of loss of effective components of Bupleurum, complex process, long cycle, etc., and achieve outstanding softening effect, easy to be absorbed, and easy to absorb. Effect

Inactive Publication Date: 2019-09-13
亳州市慈济堂中药饮片有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The object of the present invention is to provide a screening and processing method of Bupleurum, which solves the problem that the traditional screening and processing method of Bupleurum has complex process, long cycle and easy loss of active ingredients of Bupleurum

Method used

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  • Chinese thorowax root screening and processing method

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Comparison scheme
Effect test

Embodiment 1

[0022] A kind of Bupleurum screening processing method, the step comprises

[0023] (1) Impurity removal: select fresh Bupleurum bupleurum to remove impurities and residual stems;

[0024] (2) Cleaning: Soak Bupleurum bupleuri in an aqueous solution with a pH value of 5.5, add 0.04 wt% lysozyme to the solution, control the temperature at 55°C for enzymatic hydrolysis, and perform ultrasonic cleaning for 15 minutes at the same time. The frequency is 10KHz;

[0025] (3) Softening: Soak the Bupleurum root after cleaning in an aqueous solution with a pH value of 5.0, and add 0.3wt% compound enzyme in the solution, the compound enzyme is composed of cellulase and cutinase, and the cellulase and cutinase The weight ratio between the enzymes is 4:1, the temperature is controlled at 50°C, and the enzymolysis is carried out for 20 minutes; then, the Bupleurum bupleurum is fished out and drained, and then put into an ultra-low temperature box at -170°C for 18 minutes of freezing, and t...

Embodiment 2

[0029] A kind of Bupleurum screening processing method, the step comprises

[0030] (1) Impurity removal: select fresh Bupleurum bupleurum to remove impurities and residual stems;

[0031] (2) Cleaning: Soak Bupleurum bupleuri in an aqueous solution with a pH value of 5.9, add 0.05 wt% lysozyme to the solution, control the temperature at 58°C for enzymatic hydrolysis, and perform ultrasonic cleaning for 20 minutes at the same time. The frequency is 8KHz;

[0032] (3) Softening: Soak the Bupleurum root after cleaning in an aqueous solution with a pH value of 5.5, and add 0.5wt% compound enzyme in the solution, the compound enzyme is composed of cellulase and cutinase, and the cellulase The weight ratio between cutinase and cutinase is 4.5:1, the temperature is controlled at 55°C, and the enzymolysis is carried out for 23 minutes; then, the Bupleurum bupleurum is fished out and drained, and then put into an ultra-low temperature box at -175°C for 20 minutes of freezing. Then t...

Embodiment 3

[0036] A kind of Bupleurum screening processing method, the step comprises

[0037] (1) Impurity removal: select fresh Bupleurum bupleurum to remove impurities and residual stems;

[0038] (2) Cleaning: Soak Bupleurum bupleuri in an aqueous solution with a pH value of 6.2, add 00.06 wt% lysozyme to the solution, control the temperature at 60°C for enzymatic hydrolysis, and perform ultrasonic cleaning for 30 minutes at the same time. The frequency is 9KHz;

[0039] (3) Softening: Soak the Bupleurum root after cleaning in an aqueous solution with a pH value of 6.0, and add 0.7wt% compound enzyme in the solution, the compound enzyme is composed of cellulase and cutinase, and the cellulase The weight ratio between cutinase and cutinase is 5:1, the temperature is controlled at 60°C, and the enzymolysis is carried out for 25 minutes; then, the Bupleurum bupleurum is fished out and drained, and then put into an ultra-low temperature box at -180°C for 22 minutes of freezing. Then ta...

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Abstract

The invention discloses a Chinese thorowax root screening and processing method. The steps of the method include impurity removing, cleaning, softening and drying. Instead of adopting traditional stewing and softening methods, the method adopts the softening method combining enzyme treatment and ultra-low temperature crushing effects, so that softening effects can be more prominent, convenient slicing can be achieved, and processing periods can be effectively shortened; many activity factors are embedded in the fiber structure of Chinese thorowax root, and partial cellulose and hemicellulose can be degraded by cellulase, so that the whole structure can become bulky and porous, and drug effects can be achieved more easily when decoction pieces are finally boiled and more easily to be absorbed; and through the enzymatic treatment of cutinase, the hydrolysis of keratinous polymer of the cuticle of the Chinese thorowax root can be catalyzed, monomers and oligomers can be hydrolyzed, and therefore, the dissolution of effective components in the decoction pieces can be further promoted.

Description

technical field [0001] The invention relates to the technical field of processing Chinese medicinal materials, in particular to a method for screening and processing Bupleurum bupleuri. Background technique [0002] Bupleurum, the name of traditional Chinese medicine. It is a herbal medicine included in "Chinese Pharmacopoeia", and the medicinal part is the dried root of Bupleurum bupleuri or Bupleurum angustifolia. Excavated in spring and autumn, removed stems, leaves and sediment, and dried. Bupleurum is commonly used to relieve symptoms. Also known as Dixun, Shancai, Mushroom Grass, and Firewood, it is bitter in nature and slightly cold, and returns to the Liver and Gallbladder Meridians. It has the effects of reconciling the exterior and interior, soothing the liver and promoting yang. For cold and fever, alternating cold and heat, malaria, liver depression and Qi stagnation, sternocostal pain, anal prolapse, uterine prolapse, and irregular menstruation. [0003] As...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/233A61P11/00A61P29/00A61P33/06A61P1/16A61P1/00A61P15/00A61K125/00
CPCA61K36/233A61K2236/13A61K2236/15A61K2236/17A61K2236/19A61P1/00A61P1/16A61P11/00A61P15/00A61P29/00A61P33/06
Inventor 杨延峰
Owner 亳州市慈济堂中药饮片有限公司
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