Double-layer slow release ibuprofen and pseudoephedrine hydrochloride tablet

Abstract

A slow-releasing dual-layer ibuprofen-pseudoephedrine tablet is prepared from slow-releasing ibuprofen and slow-releasing pseudoephedrine hydrochloride through tabletting twice.

Description

Technical field: [0001] The invention relates to medicines, which is a double-layer sustained-release tablet of buprofen and pseudoephedrine. Background technique: [0002] Ibuprofen is a phenylpropionic acid non-steroidal anti-inflammatory analgesic, which has strong anti-inflammatory, anti-rheumatic, antipyretic and analgesic effects, and is used for rheumatoid arthritis. Its anti-inflammatory, analgesic, and antipyretic effects are similar to aspirin and phenylbutazone, and better than acetaminophen, but its side effects on the gastrointestinal tract are lighter and are easily tolerated by patients. Pseudoephedrine hydrochloride has the effect of selective vasoconstriction, eliminates congestion and swelling of nasopharyngeal mucosa, relieves nasal congestion symptoms, and has little effect on systemic blood vessels, heart rate and blood pressure. There are Buluo pseudoephedrine tablets and Buluo pseudoephedrine capsules in clinical use, which are used to treat fever, he...

AI Technical Summary

Problems solved by technology

[0003] The object of the present invention is to provide a kind of ibuprofen and pseudoephedrine double-layer sustained-release tablet, on the basis of ibuprofen and pseudoephedrine capsule, prepare a kind of sustained-release tablet, and be ibuprofen and pseudoephedrine hydrochloride Sustained-release granules are prepared separately, and compressed twice to form double-layer tablets, which not only solves the problem of taking too many times and inconvenient taking, but also separates the two main ingredients to avoid physical and chemical reactions, and make the sustained-release preparation more effective. more durable and stable