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Heart-nourishing and tranquilizing medicine and its prepn process

A technology for nourishing the mind and calming the nerves and medicine, which is applied in pharmaceutical formulations, drug combinations, nervous system diseases, etc., can solve the problems of low content of active ingredients, poor stability of preparations, and large dosage, and achieves improved product quality, purity, and improvement. effect of sleep

Active Publication Date: 2005-09-28
THE HONG KONG POLYTECHNIC UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Existing similar products are all made by traditional Chinese medicine preparation methods, the preparation technology is backward, the removal rate of invalid impurities is low, the total extract yield is high, generally more than 10%; the content of active ingredients is low, and the extract has strong moisture absorption , the stability of the preparation is poor, and the dosage is large each time

Method used

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  • Heart-nourishing and tranquilizing medicine and its prepn process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The raw materials are 5 grams of jujube kernels, 4 grams of Albizia juliensis, 4 grams of mulberries, 3 grams of schisandra, and 2 grams of cypress kernels, crushed into coarse powder, add 90 ml of water, and decoct twice, the first decoction for 2 hours, and the second decoction Boil for 1 hour, combine the decoction, filter, add to the treated D101 macroporous resin adsorption column (resin: extract weight = 0.5: 1), elute with pure water until the color of the effluent is nearly colorless, Then eluted with ethanol solution until the color of the effluent was nearly colorless, collected the ethanol eluate, recovered the ethanol under reduced pressure and concentrated to a thick paste, dried in vacuum to obtain 0.5 g of solid, crushed, granulated, and packed into 2 capsules.

Embodiment 2

[0022] The raw materials are 7 grams of jujube kernels, 3.5 grams of Albizia juliensis, 3.5 grams of mulberries, 2.1 grams of schisandra, and 2.1 grams of cypress kernels, crushed into coarse powder, add 110ml of water, and cook 3 times, the first time for 2 hours, the second and third times Each was decocted for 1 hour, the decoction liquid was combined, filtered, added to the treated D101 macroporous resin adsorption column (resin: extract weight = 1:1), and eluted with pure water until the color of the effluent was almost color, then eluted with ethanol solution until the color of the effluent was nearly colorless, collected the ethanol eluate, recovered ethanol under reduced pressure and concentrated to a thick paste, dried in vacuo to obtain 0.8 g of solid, crushed, granulated, and loaded into 2 capsules capsule.

Embodiment 3

[0024] Crush 8 grams of jujube kernels, 4 grams of Albizia juliensis, 3 grams of mulberry, 3 grams of schisandra, and 2 grams of cypress kernels into coarse powder, add 200ml of water, and cook for 3 times, the first time for 2 hours, the second and third times Each decocted for 1 hour, combined the decoction, filtered, added to the treated D101 macroporous resin adsorption column (resin: extract weight = 2:1), and eluted with pure water until the color of the effluent was almost gone. color, followed by elution with ethanol solution until the color of the effluent is nearly colorless, collect the ethanol eluate, recover ethanol under reduced pressure and concentrate to a thick paste, dry in vacuo to obtain 0.7 g of solid, pulverize, granulate, and pack into 2 capsules capsule.

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Abstract

The present invention relates to one kind of heart-nourishing and tranquilizing medicine and its preparation process. The medicine has the active components extracted from common jujube seed, albizia flower, mulberry, schisandra and arborvitae seed. The active components are prepared through crushing the medicine material, decoction, filtering, elution in adsorbing resin column first with water and then with alcohol, collecting the eluted liquid, decompression concentration to obtain extractum as the active components while recovering solvent. The active components are then prepared into various kinds of oral preparation.

Description

technical field [0001] The invention relates to a medicine for nourishing the heart and calming the nerves and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] The status of existing similar products. [0003] The status of existing similar products is shown in Table 1. [0004] name prescription composition dosage form efficacy Application range Jiannao Anshen Wan Turtle shell, pearl, sky Hemp, cinnabar, etc. Pills Brain and heart Feeling guilty, forgetful, headache Dizziness, palpitations, insomnia Anshen Oral Liquid Suanzaoren, Poria cocos, etc. oral liquid Invigorate the spleen and calm the heart Palpitations and insomnia Anshen Dingzhi Pills Suanzaoren, Poria cocos, Boziren, Dangshen, etc. Pills Nourish blood and soothe the nerves Deficiency, insomnia, palpitations Dream pu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P25/20
Inventor 曾庆忠钱忠明
Owner THE HONG KONG POLYTECHNIC UNIV
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