Preparation method of troxerutin injection

A troxerutin and injection technology, applied in the field of preparation of troxerutin injection, can solve the problems of hydroxyethylrutin derivative allergy, poor drug stability and the like, achieve improved clarity, good stability, A stable effect
CN1830434AInactive Publication Date: 2006-09-13诺氏制药(吉林)有限公司

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
诺氏制药(吉林)有限公司
Publication Date
2006-09-13
Estimated Expiration
Not applicable · inactive patent
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Abstract

An injection of troxerutin for treating obliterative syndrome, thrombophlebitis, capillary hemorrhage is prepared through ion exchange of troxerutin, mixing with the water for injection, pouring in containers, sterilizing, and lamp examining.
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Description

technical field

[0001] The invention discloses a preparation method of troxerutin injection, which contains troxerutin obtained through hydroxyethylation of rutin and water for injection. The preparation is treated with ion exchange technology to obtain troxerutin medicinal liquid, which is prepared together with water for injection, filled, sterilized, lamp-inspected and packaged to make a finished product. This process is treated with ion exchange technology to ensure that more than 99.99% of the metal ions are completely removed, ensuring that the inspection of metal ions in the preparation meets the regulations; at the same time, most of the other hydroxyethyl rutin derivatives are also removed, ensuring the hydroxy The ethyl rutin derivatives are checked to meet the regulations, and the prepared preparations have good stability, small irritation, stable curative effect, and improved clarity. For obliteration syndrome, thrombophlebitis, capillary hemorrhage, etc. Backgr...

Claims

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