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Washing device for liquid chromatography injectors

a liquid chromatography and injector technology, applied in measurement devices, scientific instruments, instruments, etc., can solve the problems of obstructing the fluid circuit ducts, chemical incompatibilities between the elastomeric materials and the solvents used for washing,

Inactive Publication Date: 2009-05-21
THERMO ELECTON
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The invention proposes a washing device for injectors in liquid chromatography equipment to avoid the drawbacks associated with the use of a piercable elastomer seal. The device has specific features that improve its performance and reliability.

Problems solved by technology

This embodiment has some problems at operating level as the duckbill valves have a limited working life and, like the partitions, can release downstream particles that have been detached during insertion of the needle; these particles are obviously contaminating and could obstruct the ducts of the fluid circuit.
Furthermore, there could be chemical incompatibilities between the elastomeric materials and the solvents used for the washing.

Method used

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  • Washing device for liquid chromatography injectors
  • Washing device for liquid chromatography injectors
  • Washing device for liquid chromatography injectors

Examples

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Embodiment Construction

[0011]With reference firstly to FIGS. 1 and 2, the washing device 10 illustrated in them consists essentially of a block 12 made of a metallic material, for example, in which a duct 14 is obtained with lead 16 for the introduction of a needle (not shown) from the outside of the equipment.

[0012]In its lower part, the block 12 is seal-connected 20 to an elongated component 18 which contains, inside, a passage 24 for the needle or other injection means, aligned with the upper duct. The lower part of the passage 24, indicated by 22, is provided internally with a coating designed to provide a seal with the outer surface of the needle or similar injection device, in a known manner, obviously when said needle is present.

[0013]Upstream of the passage 22, 24, the block 12 has a short duct 26 connected and aligned with said passage 22, 24, which ends, like the duct 14, in a valve seat 28, for example a cylindrical, are obtained in the block 12. Inside said valve seat 28 a valve body 30, also ...

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Abstract

The invention concerns a device for washing the injector in a liquid chromatography equipment, comprising a sealed passage for the injection needle and, upstream, a mobile valve for alternatively connecting said passage with the outside for introduction of the needle, or with at least one source of washing fluid.

Description

FIELD OF THE INVENTION[0001]The present invention concerns a device for washing the injector in a liquid chromatography analysis equipment.[0002]In modern chromatographic analysis equipments it is increasingly important to be sure of introducing into the chromatograph samples, generally in very small quantities, without any contamination, in particular contamination due to samples previously analysed. To ensure this, it is important, before each analysis, to wash the sample introduction equipment and the injection device in general.PRIOR ART[0003]A device of this type has already been proposed for HPLC (High Pressure Liquid Chromatography) injectors, described in EP 1275957 and U.S. Pat. No. 6,526,812. This device consists essentially of a body with an internal chamber which can be connected to a source of washing fluid and which can be accessed via an injection needle which is inserted through a duct external to the chamber and passing through the chamber until it reaches a passage...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): G01N30/20
CPCG01N30/20G01N2030/202G01N2030/201
Inventor ZILIOLI, GIACINTOMAGNI, PAOLOPELAGATTI, STEFANO
Owner THERMO ELECTON