8 results about "Vasomotor symptom" patented technology

Aspects of disclosure relate to a composition and methodology for treating menopause symptoms utilizing a cannabinoid-based nanoplatform composition. The composition includes phytocannabinoids like CBD, CBG, and CBN, alongside isoflavones and polyphenols, all integrated into nanoplatform designed for enhanced bioavailability and controlled release. The formulation is designed to alleviate key menopause-related issues, including vasomotor symptoms (VMS), genitourinary syndrome of menopause (GSM), bone loss, mood disturbances, and sleep disorders, while addressing cardiovascular disease (CVD) risks. The composition combines cannabinoids, such as CBD, with isoflavones and polyphenols, and is incorporated into nanoplatforms for enhanced delivery and efficacy. Additionally, the disclosure includes a kit comprising oral capsules, intravaginal ovules, and instructions for use. The capsules contain a blend of cannabinoids, flavonoids, and polyphenols, while the ovules are composed of CBD and cocoa butter. The kit provides a comprehensive solution for managing menopause symptoms and mitigating cardiovascular risks.

The invention features methods for preventing or treating CGRP associated disorders such as vasomotor symptoms and / or headaches (e.g., migraine, cluster headache, and tension headache) by administering an anti-CGRP antagonist antibody. Compositions for use in the disclosed methods are also provided. Antagonist antibody G1 and antibodies derived from G1 directed to CGRP are also described.

The present invention relates to a nitrogen-containing heteropolycyclic derivative modulator, a preparation method therefor and the use thereof. In particular, the present invention relates to a compound represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing the compound, and the use thereof as a modulator in the preparation of drugs for treating menopausal syndrome, polycystic ovarian syndrome, uterine fibroids, schizophrenia, irritable bowel syndrome, vasomotor symptoms, breast cancer and related disorders thereof, wherein each substituent in general formula (I) is the same as defined in the description.

The present disclosure relates to methods of treating vasomotor symptoms in a female subject in need thereof by administering a therapeutically effective amount of elinzanetant or a pharmaceutically acceptable salt or deuterated thereof, wherein the female subject is concurrently administered with a moderate CYP3A4 inhibitor.

The invention discloses a traditional Chinese medicine composition for improving related symptoms of ovarian insufficiency and application of the traditional Chinese medicine composition, and belongs to the field of traditional Chinese medicines. The method mainly comprises the following steps: selecting 6-15 parts by weight of artemisia apiacea, 6-12 parts by weight of scutellaria baicalensis, 9-18 parts by weight of morinda officinalis, 15-30 parts by weight of light wheat, 12-24 parts by weight of prepared rehmannia root, 9-18 parts by weight of lily, 3-9 parts by weight of prepared common monkshood daughter root and 15-30 parts by weight of calcined oyster shell, cleaning the raw material medicines to remove non-medicinal parts and impurities, properly crushing the calcined oyster shell to facilitate dissolution of effective components, and drying to obtain the traditional Chinese medicine composition. Soaking the cooked radix aconiti lateralis praeparata slices in saline water, and cooking to reduce the toxicity for later use; through scientific compatibility of traditional Chinese medicines such as artemisia apiacea, scutellaria baicalensis and morinda officinalis, and by following the treatment method of clearing the upper part and warming the lower part and traffic heart and kidney, comprehensive intervention is realized, so that vasomotor symptoms such as hectic fever, night sweat and the like can be remarkably improved, sleep disorders such as insomnia, upset and the like can be relieved, osteoporosis can be prevented and improved through the effects of tonifying kidney and strengthening bone, and meanwhile, the immune imbalance state can be regulated.

The present invention relates to benzothiophene derivatives modulators, processes for their preparation and use. In particular, the present invention relates to compounds of general formula (I), processes for their preparation, pharmaceutical compositions containing them and their use as modulators in the preparation of medicaments for the treatment of menopausal symptoms, polycystic ovary syndrome, uterine fibroids, schizophrenia, irritable bowel syndrome, vasomotor symptoms, breast cancer and related conditions, wherein the substituents of general formula (I) are as defined in the description.

1. The name of the design product: electronic device's vasomotor symptom severity record graphical user interface. 2. The use of the design product: for an electronic device. 3. The design points of the design product: in the graphical user interface. 4. The picture or photo that best indicates the design points: design 1 interface change state diagram 2. 5. The usual design, omit other views of the electronic device. 6. Design 1 is designated as the basic design. 7. The use of the graphical user interface: for patients to record the severity of symptoms of vasomotor symptoms. 8. Other circumstances that need to be explained: the user clicks on any one of the buttons representing the degree of "mild", "moderate" and "severe" according to the degree of hot flashes in the main view of design 1, the interface jumps to design 1 interface change state diagram 1, clicks on the "confirm" button of the pop-up window in design 1 interface change state diagram 1, the interface jumps to design 1 interface change state diagram 2; the human-computer interaction mode of design 2 is the same as that of design 1.

Provided herein is method of treating vasomotor symptoms (VMS) in a breast cancer patient being treated with an endocrine therapy drug comprising administering fezolinetant.