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2 results about "Vasomotor symptom" patented technology
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Vasomotor symptoms refer to the symptoms that accompany menopause or peri-menopause that are associated with the sudden opening of blood vessels that are close to the skin. This is mostly due to the fluctuations in the hormone levels in the blood stream. Examples of Vasomotor symptoms include; hot flashes, sweats, night sweats and flushes.
Nitrogen-containing heteropolycyclic derivative inhibitor, preparation method therefor and use thereof
PCT designated stageWO2026114366A1Organic active ingredientsNervous disorderVasomotor symptomDepressant
The present invention relates to a nitrogen-containing heteropolycyclic derivative modulator, a preparation method therefor and the use thereof. In particular, the present invention relates to a compound represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing the compound, and the use thereof as a modulator in the preparation of drugs for treating menopausal syndrome, polycystic ovarian syndrome, uterine fibroids, schizophrenia, irritable bowel syndrome, vasomotor symptoms, breast cancer and related disorders thereof, wherein each substituent in general formula (I) is the same as defined in the description.
Owner:SHANGHAI HANSOH BIOMEDICAL CO LTD +1
Benzophenol derivatives as inhibitors of the enzyme dihydroorotate dehydrogenase, process for their preparation and use
The present invention relates to benzothiophene derivatives modulators, processes for their preparation and use. In particular, the present invention relates to compounds of general formula (I), processes for their preparation, pharmaceutical compositions containing them and their use as modulators in the preparation of medicaments for the treatment of menopausal symptoms, polycystic ovary syndrome, uterine fibroids, schizophrenia, irritable bowel syndrome, vasomotor symptoms, breast cancer and related conditions, wherein the substituents of general formula (I) are as defined in the description.
Owner:SHANGHAI HANSOH BIOMEDICAL CO LTD +1