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Micro flow controlling chip DNA molecular calculating device

A microfluidic chip and DNA molecule technology, applied in the field of computer science, can solve the problems of recording and storage, impossibility and control of the computing process

Inactive Publication Date: 2007-11-14
DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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  • Abstract
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

One is that the biological operations involved in the DNA calculation and the corresponding result confirmation lack a fully integrated hardware device supporting the calculation, and of course it is impossible to control the relevant parameters; the other is that all these molecular calculations are carried out only on DNA molecules. The automatic operation of the computer is not able to record and store each calculation process, and the storage function is one of the main functions of the computer in the modern sense, and it is also a basic feature of the DNA computer that is different from the DNA calculation device.

Method used

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  • Micro flow controlling chip DNA molecular calculating device
  • Micro flow controlling chip DNA molecular calculating device
  • Micro flow controlling chip DNA molecular calculating device

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Embodiment Construction

[0059] It can be seen from Figure 1 that the microfluidic chip DNA computer mainly includes a microfluidic chip workstation, a microfluidic chip, and kits for completing various molecular reactions. The microfluidic chip workstation is composed of power supply, control device and output device. It has the functions of chip energy supply and signal collection, and also manages the control of DNA computer. The DC high-voltage power supply system of the workstation is connected to eight electrodes, and different voltages can be applied to different positions of the microfluidic chip as required to control the flow of the reaction solution between the channels as required. The detector of the microfluidic chip workstation can move relative to the chip, and detect the reaction products in the algorithmic logic unit and the storage unit respectively. The chip is the core of the entire computer, and the calculation function and storage function of the computer are all completed on th...

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Abstract

The invention is a microflow control chip DNA molecular computer, comprising operation medium, reaction medium and microflow control chip, where the operation medium comprises special sequence-containing DNA calculating molecules, intermediate operating special sequence-containing DNA transfer molecules and DNA output molecules standing for calculated results; the reaction medium comprises various biochemical enzymes for endonuclease reaction and enzyme-link reaction; and the microflow control chip is provided at least with endonuclease reaction region, enzyme-link reaction region and result output region. The invention adopts the microflow control chip technique to replace the widely used test tube or surface operation in the current DNA calculating course for the first time, and provides a practical possible platform for constructing a proper DNA computer by the character that the microflow control chip operates accurately and controllably and can be integrated in high flux and large scale.

Description

Technical field: [0001] The invention relates to computer science, molecular biology and microfluidic chip technology. In particular, a microfluidic chip DNA molecular computer, a microfluidic chip DNA molecular calculator, a microfluidic chip DNA molecular memory, a microfluidic chip specially used for a DNA molecular computer, and a special microfluidic chip for DNA Kit for microfluidic chips for molecular computers. Background technique: [0002] DNA computing is a new way of thinking about computing, but also about chemistry and biology. Although the biological and mathematical processes have their own complexities, they have an important commonality, that is, all the complex structures of organisms are actually obtained after some simple processing of the original information encoded in the DNA sequence, and seeking The value of a computable function with variable W can also be realized by the composition of a series of simple functions with variable W. [0003] The ...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06N3/00
Inventor 林炳承解华李博伟黄振德丁永生
Owner DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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