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Medicine for treating cardiac and cerebral vascular disease

A technology for cardiovascular and cerebrovascular diseases and drugs, which is applied in the field of medicine to achieve the effects of anti-platelet aggregation, reducing the scope and increasing myocardial blood supply

Inactive Publication Date: 2009-09-02
SHANDONG XUANZHU PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] At present, the use of Danshen, Radix Paeoniae Rubra, Radix Curcuma and Safflower, or the interaction and compatibility of Danshen, Radix Radix Radix Radix Paeoniae Alba, Radix Curcuma, Safflower and Astragalus for the preparation of drugs for treating cardiovascular and cerebrovascular diseases has not been reported yet.

Method used

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  • Medicine for treating cardiac and cerebral vascular disease
  • Medicine for treating cardiac and cerebral vascular disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] Embodiment 1: the preparation of pharmaceutical tablet of the present invention

[0070] Danshen 750g Radix Paeoniae Rubra 750g Curcuma 50g Safflower 300g Astragalus 750g

[0071] Add water to decoct the above-mentioned parts by weight of Salvia miltiorrhiza, Radix Paeoniae Rubra, Curcuma, Safflower and Radix Astragali three times, the decoction time is 2 hours, 1 hour, 1 hour respectively, the amount of water added is 10 times the amount, filter, and the filtrate is concentrated to The relative density is 1.05~1.10, add ethanol until the alcohol content is 70%, alcohol precipitation, refrigerate for 24 hours, filter, recover the ethanol from the filtrate and concentrate it to a thick paste, concentrate it to dryness under reduced pressure, crush it into a powder, and add a binder , disintegrating agent and lubricant are made into granules, dried and pressed into 1000 tablets.

Embodiment 2

[0072] Embodiment 2: the preparation of medicine capsule of the present invention

[0073] Danshen 1000g Radix Paeoniae Rubra 1000g Turmeric 400g Safflower 600g

[0074] Add water to decoct the salvia miltiorrhiza, red peony root, turmeric and safflower three times by adding water for 2 hours, 1 hour and 1 hour respectively, and add 10 times the amount of water, filter, and concentrate the filtrate to a relative density 1.05-1.10, add ethanol until the alcohol content is 70% alcohol precipitation, refrigerate for 24 hours, filter, recover the ethanol from the filtrate and concentrate it to a thick paste, concentrate it to dryness under reduced pressure, crush it into a medicinal powder, pack it into 1000 hard capsules .

Embodiment 3

[0075] Embodiment 3: the preparation of pharmaceutical granule of the present invention

[0076] Salvia miltiorrhiza 625g, red peony 625g, turmeric 500g, safflower 375g, astragalus 625g

[0077] Add water to decoct the above-mentioned parts by weight of Salvia miltiorrhiza, Radix Paeoniae Rubra, Curcuma, Safflower and Radix Astragali three times, the decoction time is 2 hours, 1 hour, 1 hour respectively, the amount of water added is 10 times the amount, filter, and the filtrate is concentrated to The relative density is 1.05-1.10, add ethanol until the alcohol content is 70%, alcohol precipitation, refrigerate for 24 hours, filter, recover the ethanol from the filtrate and concentrate it to a thick paste, concentrate it to dryness under reduced pressure, grind it into a medicinal powder, add powdered sugar, The binder comes in packs of 1000 pellets.

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PUM

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Abstract

The invention belongs to the technical field of medicine, and discloses a medicine for cardiovascular and cerebrovascular diseases, a preparation method and application thereof. The medicine is mainly prepared from salvia miltiorrhiza, red peony, curcuma, safflower, or salvia miltiorrhiza, red peony, turmeric, safflower and astragalus in a certain weight ratio. It can be made into any clinically or pharmaceutically acceptable dosage form, preferably an oral preparation. The drug has the effects of promoting blood circulation and removing blood stasis, replenishing qi and nourishing the heart, dredging channels and relieving pain, and can be used to treat coronary heart disease, chest tightness caused by qi deficiency and blood stasis, angina pectoris, hypertension, hyperlipidemia, arteriosclerosis and other diseases, and the effect is remarkable.

Description

1. Technical field [0001] The invention relates to a medicine for cardiovascular and cerebrovascular diseases and its preparation method and application. It is mainly prepared from salvia miltiorrhiza, red peony root, turmeric and safflower, and astragalus can be added, and belongs to the technical field of medicine. 2. Background technology [0002] Coronary heart disease is a frequently-occurring disease among middle-aged and elderly people. It is mainly due to coronary atherosclerosis and coronary artery spasm caused by predisposing factors, which temporarily aggravates myocardial ischemia and causes angina pectoris. In severe cases, it may manifest as myocardial infarction and arrhythmia. [0003] Coronary heart disease belongs to the category of "chest pain" and "heart pain" in traditional Chinese medicine. Its disease location is in the heart. Traditional Chinese medicine believes that the occurrence of this disease is related to factors such as old age and physical we...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P9/10
Inventor 黄振华
Owner SHANDONG XUANZHU PHARMA TECH CO LTD
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