Continuous dynamic gathering type beastie inducing fluorescence molecule imaging system

Abstract

A dynamic dada sampling system and method is disclosed for in vivo small animal fluorescence molecular imaging and dual-modality molecular imaging. The system comprises a computer, a rotation stage for animal suspension driven by a motor, and a fluorescence excitation-detection apparatus. The fluorescence excitation-detection apparatus comprises a fluorescence excitation module and a fluorescencedetection module. The CCD device of the fluorescence detection module is connected to a computer through an interface controller. The motor is connected to a computer through RS232 interface. The process of dynamic data acquisition is as follows: a fluorescent probe is injected into a small animal in order to target specific cells or tissues; a small animal is vertically hung on a rotation stage after anesthesia; the fluorescence imaging detection module acquires the emitting light continuously.; The present invention can provide 360 degree imaging quickly, efficiently, and non-invasively.

Description

technical field [0001] The invention relates to an imaging system, in particular to a continuous dynamic collection type small animal-induced fluorescent molecular imaging system. Background technique [0002] After medical imaging technology experienced structural imaging and functional imaging, since the 1990s, with the development of biological and genetic technology and the improvement of imaging technology, new molecular imaging technology has emerged. Inject tracers or markers in living organisms to mark specific molecules or cells, and molecular imaging technology can obtain information on the cellular, gene, and molecular levels related to the physiological or pathological processes of organisms, thereby providing information on gene function positioning and cell growth. The mechanism of development and mutation process, new drug development, etc. provide effective means of information acquisition and analysis and processing. The existing small animal in vivo molecu...

AI Technical Summary

Problems solved by technology

[0006] For small animal in vivo optical imaging systems, dual-mode imaging systems have also appeared, such as the combination of optical imaging and X-ray imaging. At the same time, the acquisition modes of this type of system are mostly serial in time, and it is impossible to acquire image information in both modes at the same time

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