Method for overall monitoring kidney-tonifying body-strengthening tablet quality

A kidney-tonifying, whole-process technology, applied in the field of monitoring the quality of Bushen Qiangshen Tablets throughout the process, to achieve the effects of reducing the possibility of manual processing, easy production process, and scientific adjustment

Inactive Publication Date: 2007-08-08
MASSON GROUP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The intermediate extract and the finished product of Bushen Qiangshen Tablets have no research reports on the detection of multiple components at one time by HPLC and the establishment of fingerprints

Method used

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  • Method for overall monitoring kidney-tonifying body-strengthening tablet quality
  • Method for overall monitoring kidney-tonifying body-strengthening tablet quality

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0050] 1. Construction of HPLC standard fingerprint

[0051] 1. Instruments and reagents

[0052] 1.1 Instrument

[0053] Agilent 1100 liquid chromatograph, DAD detector; Shanghai Brain SB5200 ultrasonic cleaner.

[0054] 1.2 Reagent

[0055] Methanol, analytically pure; acetic acid, analytically pure; acetonitrile, chromatographically pure, produced by Dima Company; ultra-pure water, Wahaha purified water; 10 batches of medicinal materials of dog spine produced in Gansu; 10 batches of medicinal materials of Cuscuta produced in Inner Mongolia; 10 batches of medicinal materials of dog spine produced in Guangxi ; 10 batches of intermediate extracts; 10 batches of finished tablets;

[0056] The above-mentioned medicinal materials of Epimedium, Cuscuta, Gouji, Fructus Rosa, and Ligustrum lucidum all meet the national standard requirements of the corresponding medicinal materials in the Pharmacopoeia, and the finished tablets meet the drug standard requirements of our company ap...

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PUM

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Abstract

The invention relates to a method for detecting the quality of kidney tonifying tablet, which comprises that first, building the standard fingerprint diagram of barren wort, doddor, woodwardic, middle extract and final tablet; second, checking the fingerprints of tested barren wort, doddor, woodwardic, middle extract and final tablet; third, comparing the fingerprints with standard ones. The groups with met similarity can be used as material to be used in production, and the qualified middle extract is used in next process, and the final tablet is used as final product. The invention can realize full-process quality detection.

Description

technical field [0001] The invention relates to a method for monitoring the quality of Bushen Qiangshen Tablets in the whole process, which comprises constructing HPLC standard fingerprints of Epimedium medicinal material, Cuscuta medicinal material, dog spine medicinal material, intermediate extract and finished tablet respectively, and using the standard fingerprint spectrum to monitor Sanwei Methods for the quality of medicinal materials, intermediate extracts, and finished tablets. Background technique [0002] Bushen Qiangshen tablet is a national standard drug. It is made of 5 herbs: epimedium, rosacea, privet, dodder and dog ridge. Among them, Epimedium, Fructus Rosa, and Fructus Ligustrum are decocted with water and concentrated to form an intermediate extract; Cuscuta Fructus and Glycyrrhizae are crushed into fine powder, and then mixed evenly with the above-mentioned intermediate extract and appropriate amount of auxiliary materials to make tablets. The key part ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/738A61P1/14A61P13/12G01N30/02
Inventor 侯峰刘芳华文俊莫启武程朝晖王宝东王鸿昶刘汉槎
Owner MASSON GROUP
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