Method for overall monitoring for kidney-tonifying body-strengthening tablet quality

A technology of fingerprint and technology detection, which is applied in the field of quality detection of Bushen Qiangshen Tablets with fingerprint technology, to achieve the effects of easy production process, strong identification and stable drug quality

Inactive Publication Date: 2011-08-31
MASSON GROUP
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The intermediate extract and the finished product of Bushen Qiangshen Tablets have no research reports on the detection of multiple components at one time by HPLC and the establishment of fingerprints

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for overall monitoring for kidney-tonifying body-strengthening tablet quality
  • Method for overall monitoring for kidney-tonifying body-strengthening tablet quality
  • Method for overall monitoring for kidney-tonifying body-strengthening tablet quality

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0050] 1. Construction of HPLC standard fingerprint

[0051] 1. Instruments and reagents

[0052] 1.1 Instrument

[0053] Agilent 1100 liquid chromatograph, DAD detector; Shanghai Brain SB5200 ultrasonic cleaner.

[0054] 1.2 Reagent

[0055] Methanol, analytically pure; acetic acid, analytically pure; acetonitrile, chromatographically pure, produced by Dima Company; ultra-pure water, Wahaha purified water; 10 batches of medicinal materials of dog spine produced in Gansu; 10 batches of medicinal materials of Cuscuta produced in Inner Mongolia; 10 batches of medicinal materials of dog spine produced in Guangxi ; 10 batches of intermediate extracts; 10 batches of finished tablets;

[0056] The above-mentioned medicinal materials of Epimedium, Cuscuta, Gouji, Fructus Rosa, and Ligustrum lucidum all meet the national standard requirements of the corresponding medicinal materials in the Pharmacopoeia, and the finished tablets meet the drug standard requirements of our company ap...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The present invention relates to a method for detecting the quality of kidney tonifying tablet using fingerprints, which comprises the following steps: first, building the standard fingerprint diagram of barren wort, doddor, woodwardic, middle extractum and final tablet; second, checking the fingerprints of tested barren wort, doddor, woodwardic, middle extract and final tablet; third, comparing the fingerprints of the three ingredients to be tested with each standard fingerprint. The groups with met similarity can be used as material to be used in production, and the qualified middle extract is used in next process, and the final tablet is used as final product. The method for detecting the quality of kidney tonifying tablet using fingerprints of the present invention can realize full-process quality monitoring including crude medicine and midbody extractum so that the whole productive technology is more easy to be controlled and the adjustment is more scientific and reasonable, thus eventually obtaining stable and consistant product quality.

Description

technical field [0001] The invention relates to a method for detecting the quality of Bushen Qiangshen Tablets by using fingerprint technology, which comprises constructing HPLC standard fingerprints of Epimedium medicinal materials, Cuscuta medicinal materials, dog spine medicinal materials, intermediate extracts and finished tablets respectively, and using standard fingerprint A method for monitoring the quality of Sanwei medicinal materials, intermediate extracts, and finished tablets by graph. Background technique [0002] Bushen Qiangshen tablet is a national standard drug. It is made of 5 herbs: epimedium, rosacea, privet, dodder and dog ridge. Among them, Epimedium, Fructus Rosa, and Fructus Ligustrum are decocted with water and concentrated to form an intermediate extract; Cuscuta Fructus and Glycyrrhizae are crushed into fine powder, and then mixed evenly with the above-mentioned intermediate extract and appropriate amount of auxiliary materials to make tablets. T...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): A61P1/14A61P13/12G01N30/02A61K36/738
Inventor 侯峰刘芳华文俊莫启武程朝晖王宝东王鸿昶刘汉槎
Owner MASSON GROUP
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap