Surface treatment technique of macromolecular material for cell culture

Abstract

The invention discloses a surface processing technique of biological medical macromolecular material, which comprises the following steps: placing cell culture container into plasma processor; introducing oxygen, nitrogen or other plasma gas under vacuum or negative pressure; discharging the plasma generator; forming plasma layer on the inner surface of cell culture container; improving biological compatibility of macromolecular material.

Description

technical field [0001] The invention relates to a polymer material surface treatment technology, in particular to a polymer material surface treatment technology for cell culture. Background technique [0002] In my country's biomedical industry, plastics and glass are usually widely used as containers for sterile cell culture. Glass containers can be used repeatedly, but there are defects such as poor cell adhesion performance, difficulty in washing, easy cross-contamination, and damage and infection to people after damage; only polymer materials that have undergone surface modification in plastics have the ability to make cells Adherence, division, growth and secretion of biologically active substances. [0003] Plasma is composed of a large number of free electrons and ions, and appears as an ionized gas that is approximately electrically neutral on a macroscopic level. It is another aggregation state of matter—plasma state, also known as the fourth state of matter. . ...

AI Technical Summary

Problems solved by technology

The power supply can affect the processing time; too high or too low working pressure will lead to unstable plasma and reduce the efficiency of plasma processing; long processing time will make the treated surface more active, but too long Can cause overprocessing; too high a power supply and too long a treatment time will affect the temperature in the plasma processor chamber