Method for preparing Chinese traditional combination capsule for treating cancer and the product thereof

The technology of a composition and traditional Chinese medicine is applied in the directions of drug combination, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc. and other problems, to achieve the effect of stable release, slow release, and reduced irritation

Active Publication Date: 2007-10-31
BEIJING ASIA EAST BIO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, cantharidin is highly toxic and strongly irritating to the epidermis and mucous membranes
The human body can be poisoned by taking a small amount, so it is difficult to reach the effective blood concentration in the human body, especially in the lesion of liver cancer, so that the therapeutic effect is not obvious
Capsules prepared by the standard method issued by the ministry, the mylabris extract is directly loaded into the capsule, which will cause strong irritation to the gastrointestinal tract, and patients often experience nausea, vomiting and other gastrointestinal discomfort after taking it

Method used

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  • Method for preparing Chinese traditional combination capsule for treating cancer and the product thereof
  • Method for preparing Chinese traditional combination capsule for treating cancer and the product thereof
  • Method for preparing Chinese traditional combination capsule for treating cancer and the product thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Weigh 23.8g of Mylabris, 59.5g of Ginseng, 297.5g of Astragalus, 297.5g of Acanthopanax, 95g of Trigonum, 357g of Scutellaria barbata, 95g of Curcuma, 119g of Cornus officinalis, 119g of Ligustrum lucidum, 2.4g of bear bile powder, and 59.5g of licorice , in addition to bear bile powder, ginseng, dogwood, Ligustrum lucidum, Scutellaria barbata were crushed into fine powder, and sieved for later use; Mylabris was extracted by soaking 3 times in chloroform, 95.2ml each time, soaked for 72 hours, combined the extracts, and used super Filtrate with membrane filtration technology, recover chloroform, concentrate to thick paste, relative density is 1.00-1.20; use beeswax to encapsulate the cantharis extract: weigh the beeswax whose weight is twice the weight of the cantharis extract, put it in a single frying pan Internally heat to melt (100°C), add the mylabris extract, stir while adding, heat (100°C) to keep it in a molten state, after it is uniform, pour it into a container...

Embodiment 2

[0039] Weigh 23.8g of Mylabris, 59.5g of Ginseng, 297.5g of Astragalus, 297.5g of Acanthopanax, 95g of Trigonum, 357g of Scutellaria barbata, 95g of Curcuma, 119g of Cornus officinalis, 119g of Ligustrum lucidum, 2.4g of bear bile powder, and 59.5g of licorice , in addition to bear bile powder, ginseng, dogwood, Ligustrum lucidum, Scutellaria barbata were crushed into fine powder, and sieved for later use; Mylabris was extracted by soaking 3 times in chloroform, 95.2ml each time, soaked for 72 hours, combined the extracts, and used super Filtrate with membrane filtration technology, recover chloroform, concentrate to a thick paste, and the relative density is 1.00-1.20; use cantharidin extract to include: weigh the cantharidin extract with a weight twice that of the cantharidin extract, and put it in a single Heat it in a frying pan to melt (90°C), add the extract of mylabris extract, stir while adding, heat (100°C) to keep it in a molten state, after it is uniform, pour it int...

Embodiment 3

[0041] Weigh 47.6g of Mylabris, 119g of Ginseng, 595g of Astragalus, 595g of Acanthopanax, 190g of Sanleng, 714g of Scutellaria Scutellariae, 190g of Curcuma, 238g of Cornus officinalis, 138g of Ligustrum lucidum, 4.8g of bear bile powder, 119g of licorice, and remove bear bile For powder, ginseng, cornus officinalis, Ligustrum lucidum, Scutellaria barbata are crushed into fine powder, and sieved for later use; Mylabris is extracted by soaking in chloroform three times, 190.4ml each time, soaked for 72 hours, combined extracts, and filtered by ultrafiltration membrane Technical filtration, reclaim chloroform, concentrate to thick paste, relative density is 1.00-1.20; Use beeswax to enclose the cantharis extract: get the beeswax that weight is 2 times of the cantharis extract weight, heat in single frying pan and make dissolving ( 100°C), add the mylabris extract, stir while adding, heat (100°C) to keep it in a molten state, after it is uniform, pour it into the container, cool,...

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Abstract

The invention relates to a Chinese pharmaceutical composition for treating tumor and process for preparation, wherein the pharmaceutical composition is prepared from raw materials including cantharis, ginseng, astragalus root, acanthopanax root, burred tuber, barbat skullcap, zedoary, cornus officinalis, ligustrum japonicum, bear's gall powder and licorice root.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine composition capsule for treating cancer and a product thereof, belonging to the technical field of traditional Chinese medicine pharmacy. Background technique [0002] The incidence and mortality of cancer are increasing year by year, which seriously threatens human health and has become one of the main causes of human death. Western medicine treatment is mainly based on surgery, radiotherapy, and chemotherapy. However, chemotherapy or radiotherapy often causes nausea, loss of appetite, changes in blood images, and impairment of immune function. While cancer cells are inhibited or partially killed, the human body is normal. Tissue cells are correspondingly greatly destroyed and damaged, so many patients cannot persist in completing the course of radiotherapy and chemotherapy, and lose the opportunity for effective and optimal treatment. However, traditional Chinese medicin...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/48A61K47/44A61P35/00A61K35/64A61K35/413A61K47/69
Inventor付立家付建家
OwnerBEIJING ASIA EAST BIO PHARMA CO LTD