21 results about "Scutellaria barbata" patented technology

The invention provides an anti-cancer medicine and food homologous composition and a preparation method thereof. The composition is prepared from the following components in parts by weight: 5 to 10 parts of lipoic acid, 30 to 50 parts of nano curcumin, 2 to 7 parts of berberine, 50 to 100 parts of beta-glucan, 15 to 35 parts of polymethylacrylic acid, 15 to 25 parts of herba hedyotidis diffusae extract, 7 to 15 parts of scutellaria barbata baicalein, 25 to 55 parts of astragalus polysaccharide, 8 to 18 parts of coix seed ester and 10 to 15 parts of cordyceps cicadae. Through a space-time targeting synergistic release mechanism of a bionic nanocellulose skeleton and in combination with pH / enzyme double-response intelligent regulation and control, three-stage precise synergistic effects of oxidation resistance, apoptosis promotion and immune activation are realized, the limitation that a traditional medicinal and edible composition is poor in targeting property, low in synergistic efficiency and uncontrollable in toxicity is broken through, and the medicinal and edible composition has a broad application prospect. High-efficiency and low-toxicity tumor multi-channel synergistic intervention is achieved in a natural component system for the first time, and the actual effect of the whole medicinal and edible composition on cancer and swelling resistance is improved.

This invention provides a traditional Chinese medicine preparation for promoting blood circulation and relieving pain, and its preparation method, relating to the field of traditional Chinese medicine pharmaceutical technology. The preparation is made from the following parts by weight of traditional Chinese medicine raw materials: 10-30 parts of Polygonatum sibiricum, 10-30 parts of Spatholobus suberectus, 10-30 parts of Curcuma longa, 5-20 parts of Sparganium stoloniferum, 5-20 parts of Areca catechu peel, 5-20 parts of Polygonum hydropiper, 5-20 parts of Rhizoma Scutellariae, 1-5 parts of Artemisia argyi, 5-20 parts of Solanum nigrum, 5-20 parts of Catechu, 10-30 parts of Scutellaria barbata, 5-20 parts of Aristolochia debilis, 10-30 parts of Astragalus membranaceus, and 5-20 parts of Artemisia argyi oil. The traditional Chinese medicine preparations described in this invention differ from those that typically enhance the efficacy of a single herb. Instead, they exhibit a synergistic relationship where one plus one equals more than two. The principal, assistant, adjuvant, and guide herbs complement each other, combining both tonifying and purging effects. This approach effectively promotes the dissipation of blood stasis, unblocks the flow of qi and blood in the meridians, eliminates local inflammation, and reduces swelling and pain. Simultaneously, it nourishes the tendons and bones, supports the body's vital energy, and enhances the body's ability to resist pathogens and repair damage. Thus, it comprehensively alleviates pain caused by various factors, achieving the goals of promoting blood circulation, removing blood stasis, clearing the meridians, reducing inflammation and swelling, and relieving pain.

The invention relates to application of a traditional Chinese medicine composition in preparation of a medicine for preventing or treating myelodysplastic syndrome and related complications thereof. The traditional Chinese medicine composition comprises sculellaria barbata, astragalus membranaceus, angelica sinensis, nightshade, radix curcumae, red ginseng, duchesnea indica, saussurea involucrata, cyclea verticillata and salvia miltiorrhiza. The traditional Chinese medicine composition has a good prevention and treatment effect on myelodysplastic syndrome and related complications thereof, can effectively inhibit proliferation of hematological tumor cells, and also can inhibit proliferation of the myelodysplastic syndrome by increasing the hemoglobin level, reducing the inflammatory cytokine level and reducing the proportion of peripheral blood T cells. Anemia, inflammation and low immune function caused by the myelodysplastic syndrome can be treated. The invention provides an effective strategy for prevention or treatment of myelodysplastic syndrome and related complications thereof, and provides a new direction for application of the traditional Chinese medicine composition.

The invention relates to a KASP molecular marker associated with scutellarin of erigeron breviscapus and application of the KASP molecular marker, and belongs to the technical field of genetic engineering. The primers of the KASP molecular marker associated with the scutellarin of the erigeron breviscapus comprise a forward primer 1, a forward primer 2 and a common reverse primer; the nucleotide sequence of the forward primer 1 is as shown in SEQ ID NO. 1; the nucleotide sequence of the forward primer 2 is as shown in SEQ ID NO. 2; the nucleotide sequence of the common reverse primer is as shown in SEQ ID NO.3. By utilizing the KASP technology, the SNP site and the corresponding primer combination provided by the invention not only improve the plant variety selection efficiency, but also are beneficial to shortening the breeding cycle and accelerating the cultivation of high-quality plant varieties. The markers have good genetic stability and high resolution, are suitable for high-throughput detection, and have significant application value in the field of plant breeding.

This invention belongs to the field of gastric disease treatment, specifically relating to a traditional Chinese medicine composition for treating chronic atrophic gastritis with intestinal metaplasia and its preparation method. The traditional Chinese medicine composition for treating chronic atrophic gastritis with intestinal metaplasia comprises the following raw materials in parts by weight: Agrimonia pilosa 10-15 parts, Cyperus rotundus 8-10 parts, Scutellaria barbata 10-15 parts, Lobelia chinensis 10-15 parts, Patrinia scabiosaefolia 13-17 parts, Scutellaria baicalensis 7-11 parts, Hedyotis diffusa 10-15 parts, Prunella vulgaris 10-15 parts, Hedyotis diffusa 5-7 parts, Perilla frutescens 8-10 parts, Coptis chinensis 5-7 parts, Angelica sinensis 5-7 parts, etc. This invention focuses on the core pathogenesis of damp-heat in the spleen and stomach and stagnation of gastric collaterals. The Chinese herbal composition has the effects of clearing heat and removing dampness, regulating qi and harmonizing the stomach, nourishing blood and unblocking collaterals. Clinically, it can significantly improve the OLGA / OLGIM stage of patients with chronic atrophic gastritis with intestinal metaplasia, with a total effective rate of 65.1%, providing a safe and effective Chinese medicine solution for precancerous lesions of the stomach.

The invention belongs to the field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition for treating various difficult miscellaneous diseases, and a preparation method and application thereof. The traditional Chinese medicine composition comprises the following components in parts by weight: folium artemisiae argyi, frankincense, rhizoma acori graminei, saponin, fructus aurantii, ligusticum wallichii, cassia twig, eucommia ulmoides, scorpio, radix angelicae, asarum, rosin, realgar, radix angelicae pubescentis, loofah sponge, clove, safflower carthamus, dandelion, oldenlandia diffusa, sculellaria barbata, rose, Chinese lobelia, radix paeoniae rubra, bamboo shavings, radix clematidis, perilla leaf, radix bupleuri and rhizoma corydalis. Through compatibility and component optimization of various traditional Chinese medicinal materials, the safety, the drug effect exertion and the sustainability are remarkably improved.

This invention discloses a traditional Chinese medicine composition for treating liver fibrosis with damp-heat toxicity, comprising the following raw materials in parts by weight: 20-30 parts of processed turtle shell, 18-25 parts of Oldenlandia diffusa, 11-15 parts of Curcuma zedoaria, 20-30 parts of processed Salvia miltiorrhiza (wine-processed), 14-20 parts of Scutellaria barbata, 11-15 parts of Epimedium, 10-15 parts of Artemisia capillaris, 14-20 parts of Sedum sarmentosum, 7-10 parts of Bupleurum chinense, 7-10 parts of Curcuma longa, 6-8 parts of dried ginger, 11-15 parts of stir-fried Atractylodes macrocephala, 18-25 parts of Astragalus membranaceus, 7-10 parts of Prunus persica, 8-12 parts of Schisandra chinensis, 4-6 parts of Panax notoginseng (powder), 14-20 parts of Poria cocos, and 3-5 parts of Cinnamomum cassia. This traditional Chinese medicine composition is developed based on the principles of TCM syndrome differentiation and treatment for liver fibrosis with damp-heat toxicity, and has the expected therapeutic effect on this condition.

This invention relates to a traditional Chinese medicine composition for treating primary liver cancer. The composition is made from the following raw materials in parts by weight: 25-30 parts of *Codonopsis pilosula*, 10-15 parts of *Cremastra appendiculata*, 15-20 parts of *Scutellaria barbata*, 20-25 parts of *Curcuma zedoaria*, 10-15 parts of *Polygonum cuspidatum*, and 5-10 parts of *Citrus reticulata*. This invention also provides applications of the traditional Chinese medicine composition. The "Liver-Clearing Formula" of this invention uses a combination of various traditional Chinese herbs, focusing on "damp-heat, phlegm, qi stagnation, and blood stasis." The six herbs are combined to both attack and tonify, supporting the body's resistance and eliminating pathogenic factors, aiming to achieve the goal of strengthening the body's resistance and reducing pathogenic factors, thus achieving the effects of clearing heat and dampness, promoting qi circulation, resolving phlegm, and breaking up blood stasis. This helps improve the patient's quality of life and prognosis. At the same time, the use of this traditional Chinese medicine is expected to reduce the toxicity and enhance the efficacy of Western medicine, reducing adverse reactions and achieving the best therapeutic effect.

This invention relates to the field of traditional Chinese medicine (TCM) technology, and particularly to a TCM composition for treating tinnitus. Its ingredients include: vinegar-processed turtle shell, stir-fried jujube seed, anemarrhena rhizome, phellodendron bark, rehmannia root, white peony root, poria cocos, fleeceflower root vine, scutellaria barbata, oldenlandia diffusa, stir-fried atractylodes macrocephala, prunella vulgaris, and cicada slough. The TCM composition of this invention exhibits significant multi-dimensional beneficial effects in treating tinnitus. Compared with Western medicine treatments, it avoids the side effects such as low blood pressure, dizziness, drowsiness, and dry mouth associated with vasodilators and antidepressants, and overcomes the drawbacks of physical therapy, which only temporarily relieves symptoms and cannot cure the condition. It has the advantages of holistic conditioning and fewer side effects, providing a safe, effective, and comprehensive treatment plan for tinnitus patients, and has high clinical application value and promotional significance.

The invention relates to an improved compound cocklebur fruit traditional Chinese medicine composition for treating allergic rhinitis, which is prepared from cocklebur fruit, folium mori, rhizoma phragmitis, platycodon grandiflorum, liquorice, rhizoma atractylodis, rhizoma zingiberis, radix sophorae flavescentis, rabdosia rubescens and cortex mori radicis according to a specific weight part ratio. The improved compound traditional Chinese medicine composition with a new prescription can effectively inhibit the key biological sites of the occurrence and development of rhinitis and improve the symptoms of rhinitis, and compared with the original compound fructus xanthii prescription, the improved compound traditional Chinese medicine composition has higher treatment efficiency and wider applicability to most people.

The invention discloses an anti-breast cancer traditional Chinese medicine compound preparation as well as a preparation method and application thereof. The anti-breast cancer traditional Chinese medicine compound preparation is prepared from the following raw material medicines in parts by weight: 25-35 parts of ganoderma lucidum spore powder, 10-20 parts of edible tulip, 10-20 parts of sculellaria barbata, 20-30 parts of oldenlandia diffusa, 8-12 parts of detoxified nidus vespae, 20-30 parts of selfheal, 10-20 parts of akebia fruit and 15-25 parts of uniflower swisscentaury root. Ganoderma lucidum spore powder is used as a monarch drug instead of a tonic drug, so that the risk of excessive activation of immunity is avoided; the retention rate of triterpenes is greater than or equal to 95% and the yield of polysaccharides is greater than or equal to 15% through a segmented extraction Establishing a nidus vespae detoxification process and a nidus vespae oil limit standard; by removing tumor-promoting risk medicinal materials, introducing active synergistic components and innovating a toxicity control process, the anti-tumor activity and medication safety are remarkably improved, and the composition is suitable for adjuvant therapy of breast cancer.

This invention relates to the field of traditional Chinese medicine composition technology, and in particular to a traditional Chinese medicine composition for treating lung cancer and its preparation method, comprising composition one, composition two, and composition three; composition one, by weight parts, comprises: Astragalus membranaceus 20-45 parts, Polygonatum odoratum 15-30 parts, Ophiopogon japonicus 8-18 parts, Coix lacryma-jobi 20-45 parts, Phragmites communis 20-45 parts, and Glycyrrhiza uralensis 3-6 parts; composition two, by weight parts, comprises: Clematis armandii 9-15 parts, Actinidia chinensis root 15-30 parts, Scutellaria barbata 10-22 parts, Pinellia ternata 6-13 parts, Fritillaria thunbergii 6-13 parts, and Citrus reticulata peel 6-13 parts; composition three, by weight parts, comprises: Buthus martensii 3-8 parts. The traditional Chinese medicine composition prepared by this invention has the effects of invigorating qi and nourishing yin, clearing heat and detoxifying, resolving phlegm and dissipating nodules, and promoting blood circulation and unblocking collaterals. It overcomes the technical problems of existing anti-lung cancer chemotherapy drugs having large toxic side effects and easily developing drug resistance, as well as the limited anti-lung cancer effects of existing single or simple compound traditional Chinese medicines, and the lack of optimization in compatibility and process.

This invention discloses a medicinal ointment for treating Qi deficiency and blood stasis syndrome and its preparation method. The raw materials of the medicinal ointment include: ginseng, atractylodes macrocephala, astragalus membranaceus, rehmannia glutinosa, dandelion, chuanxiong rhizome, costus root, turmeric, salvia miltiorrhiza, peucedanum praeruptorum, apricot kernel, sparganium rhizome, scutellaria barbata, oldenlandia diffusa, licorice, and gelatinous medicinal materials. The preparation method involves decocting the medicinal formula and then adding gelatinous materials to form the ointment. This invention improves the loss of appetite and fatigue in mice with non-small cell lung cancer syndrome caused by Qi deficiency and blood stasis syndrome by modifying the traditional Chinese medicine formula and preparing it as an ointment. It reduces whole blood and plasma viscosity by tonifying Qi, activating blood circulation, and removing blood stasis, thus promoting blood flow without damaging hepatocytes and reducing the toxic side effects of the formula on the liver. Furthermore, the ointment preparation makes it convenient for patients to carry and take.

This invention discloses a traditional Chinese medicine formula for reducing toxicity and enhancing efficacy in combination with chemotherapy and immunotherapy for non-small cell lung cancer, belonging to the field of traditional Chinese medicine technology. The formula is composed of the following components by weight: Astragalus membranaceus 15-30 parts, Codonopsis pilosula 9-15 parts, Coix lacryma-jobi 15-30 parts, Poria cocos 9-15 parts, Atractylodes macrocephala (stir-fried with wheat bran) 9-15 parts, Citrus reticulata 9-15 parts, Hedyotis diffusa 15-30 parts, Scutellaria barbata 15-30 parts, Selaginella tamariscina 15-30 parts, Hedyotis diffusa 15-30 parts, Prunella vulgaris 9-15 parts, Gallus gallus domesticus (gizzard lining) 10-15 parts, stir-fried Hordeum vulgare 9-15 parts, stir-fried Hordeum vulgare 9-15 parts, and Glycyrrhiza uralensis (processed with honey) 3-6 parts. This invention can synergize with chemotherapy and immunotherapy to improve treatment efficacy and prolong survival, thus overcoming the shortcomings of existing treatments. At the same time, as a traditional Chinese medicine formula, it can significantly reduce the toxic side effects of treatment, improve the body's immune status, and relieve symptoms such as cough and chest tightness, thereby improving the patient's quality of life from multiple dimensions such as efficacy, tolerability, and physical sensation.

The invention discloses a traditional Chinese medicine composition for preventing and treating African swine fever, a pharmaceutical composition and a preparation method, and belongs to the technical field of veterinary use. The invention discloses a traditional Chinese medicine composition for preventing and treating African swine fever. The traditional Chinese medicine composition is prepared from the following raw materials: gypsum rubrum, meadowrue root and rhizome, Chinese mahonia stem, eleusine indica, sculellaria barbata, radix paeoniae rubra, cortex moutan, humifuse euphorbia herb, indigo naturalis, henon bamboo leaf and honeysuckle stem. A pharmaceutical composition for preventing and treating African swine fever is prepared into a veterinary preparation by taking the traditional Chinese medicine composition as a raw material and matching with auxiliary materials. The traditional Chinese medicine composition has good prevention and treatment effects on various viral infections such as African swine fever virus; moreover, the feed additive is low in cost, free of antibiotics and drug residues, capable of being widely applied and capable of solving major problems of the pig raising industry.

This invention provides a highly effective, broad-spectrum antibacterial, and rapidly repairing traditional Chinese medicine preparation for the treatment of skin and mucous membrane infections. It is formulated from a combination of herbs including snow lotus, buffalo horn, allium macrostemon, poria cocos, reed rhizome, dictamnus dasycarpus bark, Paris polyphylla, chrysanthemum, scutellaria barbata, physalis alkekengi, mulberry bark, and honeysuckle, based on traditional Chinese medicine theory, combined with modern medical research and clinical experience. The selected herbs are pure Chinese herbal medicines with a rational synergistic combination. Applied externally, the medicine acts directly on the affected area, resulting in rapid action. It avoids the gastrointestinal, hepatic, and renal irritation associated with oral preparations, reducing patient discomfort. The treatment course is short, the cost is low, and it is convenient to use. Clinical symptoms disappear rapidly, the efficacy is significant, and it is practical, safe, and free of toxic side effects.

This invention relates to the field of veterinary preventive and therapeutic drugs. The invention provides a traditional Chinese medicine composition for the prevention and / or treatment of porcine reproductive and respiratory syndrome (PRRS) and its preparation method, comprising the following components: Indigo naturalis, Forsythia suspensa, Arctium lappa, Dryopteris crassirhizoma, Lithospermum erythrorhizon, Taraxacum mongolicum, Rheum palmatum, Scutellaria barbata, Glycyrrhiza uralensis, Hordeum vulgare, Bupleurum chinense, and Terminalia chebula. The invention also provides a traditional Chinese medicine preparation comprising the aforementioned composition. Using the above-mentioned components in combination with the technical solution of this invention can effectively enhance the inhibitory effect on pathogenic microorganisms and the anti-PRRSV virus effect, improve immunity, and enhance the disease resistance of pigs; alleviate symptoms such as depression and loss of appetite caused by PRRSV, and regulate the gastrointestinal health of animals; at the same time, it has few toxic side effects and is less likely to induce drug resistance.

The invention discloses a targeted traditional Chinese medicine nano tablet for treating cancerous hemorrhage and a preparation method of the targeted traditional Chinese medicine nano tablet. The preparation is prepared from colla corii asini beads, carbonized hair, lily, radix stemonae, radix ophiopogonis, radix polygonati officinalis, lalang grass rhizome, dandelion, hairyvein agrimony, cacumen biotae, charred gardenia, bletilla striata, adenophora stricta, pseudo-ginseng, sculellaria barbata and oldenlandia diffusa according to a specific weight part ratio. The anti-tumor effect of treating the root causes is enhanced. According to the dosage form, the modified silicon dioxide nano-carrier is adopted for loading the medicine, and the cellulose-chitosan compound with biological responsiveness is supplemented, so that an intelligent targeted delivery system is constructed. The preparation method integrates modern processes such as ethanol reflux extraction, carbon medicine nanocrystallization, nano medicine loading and dry tabletting. The tablet disclosed by the invention has the advantages of multi-target comprehensive treatment, rapid hemostasis effect, intelligent drug release at a focus part, high bioavailability, good patient compliance and the like, and is suitable for cancerous hemorrhage caused by various malignant tumors such as gastric cancer, cervical cancer, breast cancer and the like.

The invention provides a fermented traditional Chinese medicine formula for preventing African swine fever and a preparation process thereof. The fermented traditional Chinese medicine formula is prepared from the following materials in parts by weight: 8-15 parts of herba houttuyniae, 5-10 parts of radix scutellariae, 10-15 parts of liquorice root, 10-20 parts of herba violae, 11-15 parts of flos puerariae, 10-15 parts of honeysuckle flower, 8-10 parts of rhizoma coptidis, 10-15 parts of rhizoma zingiberis, 8-15 parts of evodia lepta, 10-15 parts of peperomia blanda, 6-9 parts of rhizoma atractylodis macrocephalae, 10-15 parts of oldenlandia diffusa and 8-10 parts of herba scutellariae barbatae. The preparation method comprises the following preparation steps: step 1, cleaning the raw materials with clear water, putting the cleaned raw materials into a fermentation tank, fermenting the traditional Chinese medicine raw materials to eliminate the internal toxicity of part of traditional Chinese medicines, combining the traditional Chinese medicine formula with daily feed for pigs and drinking water according to the pathogenesis of the swine fever to achieve the effects of sterilizing, killing insects, clearing away heat and toxic materials, and improving the immunity of the swine; from the aspect of preventing respiratory tract, intestinal tract, throat and stomach diseases, the hog cholera problem is solved by preventing the hog cholera in advance.

This invention discloses a traditional Chinese medicine composition for dissolving nodules and tumors, its preparation method, and its application. The composition comprises the following components in parts by weight: 4-8g of *Taxus wallichiana*, 20-40g of *Actinidia chinensis* root, 5-25g of *Lobelia chinensis*, 20-40g of *Scutellaria barbata*, 20-40g of *Hedyotis diffusa*, 1-5g of *Scolopendra subspinipes*, 5-15g of *Curcuma zedoaria* (processed with vinegar), 5-25g of *Solanum lyratum*, 20-40g of *Astragalus membranaceus*, 5-15g of *Angelica sinensis*, 5-25g of *Pseudostellaria heterophylla*, 5-25g of *Poria cocos*, 5-25g of *Atractylodes macrocephala* (stir-fried with wheat bran), 20-40g of *Coix lacryma-jobi*, 5-15g of *Pinellia ternata* (processed with ginger), 5-15g of *Citrus reticulata* peel, and 5-15g of *Glycyrrhiza uralensis*. This formula combines tonification and purgation, nourishing qi and blood, regulating the spleen and stomach, and dissolving nodules and tumors. This invention, through the addition and subtraction of prescription drugs, can dissolve nodules and eliminate tumors in the early stage of gastric and intestinal tumor treatment, while protecting the spleen and stomach's qi and blood; in the middle stage of gastric and intestinal tumor treatment, it can strengthen the spleen, resolve dampness, detoxify and disperse nodules, combining attack and tonification; in the terminal stage of gastric and intestinal tumor treatment, it can invigorate qi and support the body's resistance, while also having anti-cancer effects.

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition and a preparation and application thereof. The traditional Chinese medicine composition is composed of a first component, a second component and a third component according to the mass ratio of 1: (1-2): (0.2-0.8), wherein the first component contains oldenlandia diffusa, sculellaria barbata and gynostemma pentaphylla, is a monarch drug and directly attacks damp toxin and blood stasis; the second component contains radix astragali, rhizoma atractylodis macrocephalae, semen coicis, polyporus umbellatus, poria cocos and taxus chinensis, is a ministerial drug and an adjuvant drug, and is used for invigorating spleen to eliminate dampness and inducing diuresis to And the third component comprises curcuma zedoary, pseudo-ginseng and lumbricus which are used as conductant drugs and can promote blood circulation to remove meridian obstruction and harmonize the drugs. Experiments and clinical verifications show that the traditional Chinese medicine composition provided by the invention can significantly improve proteinuria, regulate lipid metabolism, protect kidney structure and delay fibrosis, is suitable for patients with different conditions, is scientific in compatibility and convenient to prepare, and can be used for preparing medicines for treating membranous nephropathy with syndrome of damp toxin and blood stasis.